Gene Information

Name : Ththe16_0004 (Ththe16_0004)
Accession : YP_005639572.1
Strain : Thermus thermophilus SG0.5JP17-16
Genome accession: NC_017272
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 4100 - 5524 bp
Length : 1425 bp
Strand : +
Note : TIGRFAM: Pyruvate kinase; KEGG: pyk; pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta

DNA sequence : 
ATGCCGCCTTTTAAGCGCACCAAGATCGTGGCCACCCTGGGGCCGGCCACGGACGACAAGGAGGTGATCCGCGCCCTGGC
GGAGGCCGGGGCCGACGTCTTCCGCCTGAACTTCAGCCACGGCGCCCCCGAGGACCACAGGCGCCGGGTGGGCTGGGTGC
GGGAGGTGGCGGAGGAGCTCGGCCGAACCCTGGCCGTCCTCCAGGACCTCCAGGGCCCGAAGATCCGTGTGGGCCGTTTC
CGGGAGGGCCAGGTCCTCCTCCGCCCGGGGCAGAGGTTCGTCCTCACCGCCGAGCCCGTGGAGGGGGACGAGCACCGCGT
TTCCGTGAGCTACAAGGGGCTTCCCGAGGACGTTTCCCCAGGACAGACCCTCCTTTTGGACGACGGCCGCATCCGGCTCA
AGGTCCTGGAGGTCCGGGGCCCGGAGATTCACACGGAGGTGGAGGTGGGCGGGGTCCTCTCCAACAACAAGGGGATCAAC
ATCCCCGGGGCGGACCTCTCCATCCCCGCCCTCTCGGAGAAGGACATCCAGGACCTGGCCCTGGGGGCGGAGCTCGGGGT
GGACTGGGTGGCGGTCTCCTTCGTCCGCACGCGGGACGACCTCCTCCTCGCCCGGCACTACCTCTCCCGCTACGGCTCCA
AGGCCAGGCTCATGGCCAAGATCGAGAAGCCCTCGGCCGTGGCCCGGTTTGAGGAGATCCTGGAGGAGGCGGACGGGATC
ATGGTGGCCCGGGGGGACCTCGGGGTGGAGATGCCCCTGGAGGAGGTGCCCATCGTCCAGAAGCGCCTCATCCTCCGGTG
CATCGCCGCCGGGAAGCCGGTGATCACCGCCACCCAGATGCTGGAGTCCATGGTGCAGAACCCGAGCCCCACCCGGGCCG
AGGCCTCGGACGTGGCCAACGCCATCTTTGACGGGACCGACGCGGTGATGCTCTCCGCGGAGACGGCGGCCGGGGCCTAC
CCGGTGGAGGCGGTGGCCATGATGGCGAGGATCGCCAAGGCGGTGGAGTCCTCCCCGGAGTTCTTGCAGAAGCTCAACGT
CCTCCGCCCCGCCCCCACCCCCACCACCCAGGACGCCATCGCCCAGGCGGCGGACGACGTGGTGGAGGCGGTGGGGGCAC
GGGCCATCGTGGTCTTCACGGCCACGGGCGGCTCGGCGCGGAGGATCGCCCGCACCCGGCCCCAGGTGCCCATCCTGGCC
CTCACCCCGAACCCCGAGGTGCGGAACCAGCTGGCCTTGGTCTGGGGGGTCTACCCCCATCTCGCCCCCGACCCCCAGGA
CACCGACGACATGGTCCGCATCGCCCTCAGGGAGGTGAAGGCCCTGGGGCTCGCCCAGGTGGGGGACCGGGTGGTCATCG
CCGCTGGGGTTCCCTTCGGGGTCCGGGGGACGACGAACCTCATCCGCGTGGAGCGGGTGGGGTAG

Protein sequence : 
MPPFKRTKIVATLGPATDDKEVIRALAEAGADVFRLNFSHGAPEDHRRRVGWVREVAEELGRTLAVLQDLQGPKIRVGRF
REGQVLLRPGQRFVLTAEPVEGDEHRVSVSYKGLPEDVSPGQTLLLDDGRIRLKVLEVRGPEIHTEVEVGGVLSNNKGIN
IPGADLSIPALSEKDIQDLALGAELGVDWVAVSFVRTRDDLLLARHYLSRYGSKARLMAKIEKPSAVARFEEILEEADGI
MVARGDLGVEMPLEEVPIVQKRLILRCIAAGKPVITATQMLESMVQNPSPTRAEASDVANAIFDGTDAVMLSAETAAGAY
PVEAVAMMARIAKAVESSPEFLQKLNVLRPAPTPTTQDAIAQAADDVVEAVGARAIVVFTATGGSARRIARTRPQVPILA
LTPNPEVRNQLALVWGVYPHLAPDPQDTDDMVRIALREVKALGLAQVGDRVVIAAGVPFGVRGTTNLIRVERVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-78 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-78 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-78 45
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-78 45
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ththe16_0004 YP_005639572.1 pyruvate kinase VFG0479 Protein 2e-78 45