Gene Information

Name : Ththe16_1506 (Ththe16_1506)
Accession : YP_005641032.1
Strain : Thermus thermophilus SG0.5JP17-16
Genome accession: NC_017272
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1443940 - 1446504 bp
Length : 2565 bp
Strand : -
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: clpB; ATP-dependent chaperone protein ClpB; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGAACCTGGAACGTTGGACGCAAGCCGCCCGCGAAGCCCTGGCCCAGGCGCAGGTCCTGGCCCAAAGGATGAAGCACCA
GGCCATTGACCTGCCCCACCTCTGGGCCGTCCTCCTAAAAGACGAGGGGAGCCTTGCCTGGCGGCTTTTAGAGAAGGCCG
GGGCCGACCCCAAGGCCCTCAAAGAGGCCCAGGAGCGGGAGCTTGCCCGCCTGCCCAAGGTGGAGGGGGCCGAGGTGGGC
CAGTACCTCACACGCCGCCTCTCCGGGGCCTTGAACCGGGCTGAGGCCCTGATGGAAGAGCTTAAGGACCGCTACGTAGC
GGTGGACACCCTGGTCCTGGCCCTGAGCGAGGCCACCCCGGGGCTTCCGGGCCTCGAGACCCTGAAAAAAGCCCTACAGG
AACTAAGGGGAGGGAAGACCGTGCAGACGGAACATGCGGAAAGCACCTACAACGCTTTGGAACAGTACGGCATTGATCTG
ACCAAGCTGGCCGCCGAGGGGAAGCTGGACCCGGTGATCGGCCGGGACGAGGAGATCCGGCGCGTCATCCAGATCCTCCT
CCGGCGGACCAAAAACAACCCGGTCCTCATCGGCGAGCCCGGGGTGGGGAAGACGGCCATCGTGGAAGGCCTGGCCCAGC
GCATCGTCAAGGGAGATGTGCCCGAAGGCCTCAAGGGCAAGCGGATCATCTCCTTGCAGATGGGCTCCCTCCTCGCCGGG
GCCAAGTACCGGGGCGAGTTTGAGGAGCGCCTGAAGGCGGTGATCCAGGAGGTGATCCAGTCCCAAGGGGAGGTCATCCT
CTTCATTGACGAGCTCCACACCGTGGTGGGGGCGGGCAAGGCCGAAGGCGCCGTGGACGCCGGCAACATGCTGAAGCCCG
CCCTGGCCCGGGGGGAGCTTCGCCTCATCGGGGCCACCACCCTGGACGAGTACCGGGAGATTGAGAAAGACCCCGCCCTA
GAACGGCGCTTCCAGCCCGTGTACGTGGACGAGCCCACGGTGGAGGAGACCATCTCCATCCTCCGGGGCCTCAAGGAGAA
GTACGAGGTCCACCACGGGGTGCGCATTTCCGACAGCGCCATCATCGCCGCCGCCACCCTCTCCCACCGGTACATCACGG
AAAGGCGCCTTCCCGACAAGGCCATTGACCTCATTGACGAGGCGGCGGCCCGCCTGCGCATGGCCTTGGAAAGCGCCCCC
GAAGAGATTGACGCTTTGGAGCGGAAGAAGCTCCAGCTGGAGATTGAGCGGGAGGCGCTGAAAAAGGAGAAAGACCCAGA
CTCCCAAGAACGGCTCAAGGCCATAGAGGCGGAGATCCAGAAGCTCAGTGAGAAGATCGCCAAGCTCCGGGCCGAGTGGG
AGAAGGAAAGGGAGATCCTGAGGAAGCTCCGCGAGGCCCAGCACCGCTTGGACGAGGTCCGGCGGGAGATTGAGCTTGCC
GAGCGCCAGTACGACCTGAACCGGGCCGCTGAGCTCCGCTACGGGGAGCTTCCCAAGCTGGAGGCCGAGGTGGAGGCCCT
TTCGGAAAAGCTCCGGGGCGCCCGCTTCGTCCGCCTCGAGGTCACCGAGGAGGACATCGCCGAGATCGTCTCCCGCTGGA
CCGGCATCCCCGTATCCAAGCTTCTGGAAGGGGAAAGGGAAAAGCTCCTAAGGCTTGAGGAGGAGCTCCACAAGCGGGTG
GTGGGCCAGGACGAGGCCATAAAGGCGGTGGCCGACGCCATCCGCCGGGCGAGGGCCGGCCTAAAAGACCCGAACCGGCC
CATCGGGAGCTTCCTTTTCCTCGGGCCCACGGGGGTGGGGAAGACGGAACTGGCCAAGACCCTGGCCGCCACCCTCTTTG
ACACCGAGGAGGCCATGATCCGCATTGACATGACGGAGTACATGGAGAAGCACGCCGTCTCCCGCCTCATCGGGGCCCCG
CCCGGCTACGTGGGCTACGAGGAGGGGGGGCAGCTCACCGAGGCGGTGCGGAGGAGGCCCTACTCGGTCATCCTCTTTGA
CGAGATTGAGAAGGCCCACCCCGACGTCTTCAACATCCTCCTCCAGATCCTGGACGACGGCCGCCTCACCGACAGCCACG
GCCGCACCGTGGACTTCCGCAACACCGTCATCATCCTCACCTCCAACCTGGGGAGCCCCCTCATCCTCGAGGGCATCCAG
AAGGGCTGGCCCTACGAGCGGATCCGCGACGAGGTCTTCCGGGTGCTGCAGCAGCACTTCCGCCCCGAGTTCCTGAACCG
TCTGGACGAGATCGTGGTCTTCCGGCCCCTCACCAAGGAGCAGATCCGCCAGATCGTGGAGATCCAGCTGGGCTACCTAA
GGGAGCGCCTTTCGGAGAAGCGCATCGCCCTGGAACTCACCGAGGCCGCCAAGGACTTCCTGGCGGAAAGGGGCTACGAC
CCCGTCTTCGGGGCAAGGCCCCTCAAGCGGGTCATCCAGCGGGAGCTGGAGACGCCCCTCGCCCAGAAGATCCTGGCCGG
CGAGGTCAAGGAGGGGGACCGCGTGCAGGTGGACGTGGGGCCCGCGGGCCTCGTGTTTACGGTCCCCGCCCGGATAGAGG
CCTGA

Protein sequence :
MNLERWTQAAREALAQAQVLAQRMKHQAIDLPHLWAVLLKDEGSLAWRLLEKAGADPKALKEAQERELARLPKVEGAEVG
QYLTRRLSGALNRAEALMEELKDRYVAVDTLVLALSEATPGLPGLETLKKALQELRGGKTVQTEHAESTYNALEQYGIDL
TKLAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKGKRIISLQMGSLLAG
AKYRGEFEERLKAVIQEVIQSQGEVILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDPAL
ERRFQPVYVDEPTVEETISILRGLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAP
EEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEAEIQKLSEKIAKLRAEWEKEREILRKLREAQHRLDEVRREIELA
ERQYDLNRAAELRYGELPKLEAEVEALSEKLRGARFVRLEVTEEDIAEIVSRWTGIPVSKLLEGEREKLLRLEEELHKRV
VGQDEAIKAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMIRIDMTEYMEKHAVSRLIGAP
PGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNILLQILDDGRLTDSHGRTVDFRNTVIILTSNLGSPLILEGIQ
KGWPYERIRDEVFRVLQQHFRPEFLNRLDEIVVFRPLTKEQIRQIVEIQLGYLRERLSEKRIALELTEAAKDFLAERGYD
PVFGARPLKRVIQRELETPLAQKILAGEVKEGDRVQVDVGPAGLVFTVPARIEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-100 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-102 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-102 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ththe16_1506 YP_005641032.1 ATP-dependent chaperone ClpB VFG2084 Protein 1e-102 41