Gene Information

Name : TPChic_0964 (TPChic_0964)
Accession : YP_005631812.1
Strain : Treponema pallidum Chicago
Genome accession: NC_017268
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease protein MacB 1/2
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1047102 - 1047809 bp
Length : 708 bp
Strand : -
Note : identified by match to protein family HMM PF00005

DNA sequence : 
GTGACTCCCGTTGTTCGCGTCTGTAACGTAAGTAAGGTGTTCCCCATGGGGGATGCGGTTGTCCATGCGTTACGCGGCGT
TTCCTTTGAAATTGCCCCGGCGGAGTTTGTTTCTATCCTTGGTCCTTCGGGTTCTGGCAAAAGTACCTGCATGCACATGA
TAGGGTGCCTCGATCGTCCCTCATCAGGCAGCGTGTTCATTGCAGGGGAAAACACCGCCTGCATGAGCGAACGTGCACTT
GCACACCTGCGCAATAGGACGGTGGGTTTTGTCTTTCAGCAATATTTTTTGCTCCCAACGCTTACCGTCTTAGAGAATGT
GATGCTCCCGCTTCGCTACCAGGGAGTTGAGTATTTTGCGCGTAGGCGTCGCGCTGAAGACGAGCTCGCCAAGGTTGGCC
TGAGCGATCGGCTCGCTCATCGGCCCAGCGAGCTATCAGGAGGGCAAAAGCAGCGCGTTGCGATCGCGCGCGCGCTGGTC
ACGCGGCCGAAAATTATCGTTGCAGACGAACCTACCGGTGCCCTTGATTCAGAAACAGGTCGCTCTGTGCTCGACTTGTT
TATCGAAATTAATAAAAAAGGTACCGCGGTTATCATTGTCACGCATGATCAGGGAGTAGGAGCTCTGGCTTCTCGCTCTC
TCACGCTTAAAGATGGCAAGATAGTAGGAGATCACGTGCGGGGTCACGGGGGAGCCGATGGTGGGTGA

Protein sequence : 
MTPVVRVCNVSKVFPMGDAVVHALRGVSFEIAPAEFVSILGPSGSGKSTCMHMIGCLDRPSSGSVFIAGENTACMSERAL
AHLRNRTVGFVFQQYFLLPTLTVLENVMLPLRYQGVEYFARRRRAEDELAKVGLSDRLAHRPSELSGGQKQRVAIARALV
TRPKIIVADEPTGALDSETGRSVLDLFIEINKKGTAVIIVTHDQGVGALASRSLTLKDGKIVGDHVRGHGGADGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 4e-32 42
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-33 41
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-33 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 2e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TPChic_0964 YP_005631812.1 macrolide export ATP-binding/permease protein MacB 1/2 NC_012469.1.7686878. Protein 1e-54 50
TPChic_0964 YP_005631812.1 macrolide export ATP-binding/permease protein MacB 1/2 NC_008702.1.4606598. Protein 1e-42 46
TPChic_0964 YP_005631812.1 macrolide export ATP-binding/permease protein MacB 1/2 CP001581.1.gene798.p Protein 2e-42 43
TPChic_0964 YP_005631812.1 macrolide export ATP-binding/permease protein MacB 1/2 CP001581.1.gene598.p Protein 9e-40 42
TPChic_0964 YP_005631812.1 macrolide export ATP-binding/permease protein MacB 1/2 NC_012469.1.7685735. Protein 2e-34 42