Gene Information

Name : TPChic_0164 (TPChic_0164)
Accession : YP_005631073.1
Strain : Treponema pallidum Chicago
Genome accession: NC_017268
Putative virulence/resistance : Virulence
Product : zinc transport system ATP-binding protein TroB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 186903 - 187703 bp
Length : 801 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGGCAGAGATATCAGCAACAGCTTATGCTGTCCAGGTTGACGACCTGACGCTTGCGTATCGGCAGAAGCCGGTGCTTTG
GGACGTGGATGTGCGTATTCCAGAGGGGGTTATCGAGGCCATTATCGGTCCTAATGGGGCGGGCAAGTCGACCCTATTGA
AGGCGATCATGGGTCTTCTGCCTCTCGCTTCCGGAGAGGTGCGTGTCTTTGGGCGTCCTTTTTCAAAAGAGCGGCGACGT
GTTGCGTATGTCCCGCAGCGCAGTGCAGTGGATTGGGATTTCCCTACTACCGTTTTTGATGTGGTGCTCATGGGTTCGTA
CGGTTCGCTCGGTTGGATTCTTCGTCCGGGAAAAAGAGAAAAGGCGCGTGCCCGGGAAGCGATCGAGGAAGTAGGAATGG
GCGCCTTTTTAGACCGACAAATCAGTGAGCTTTCAGGCGGTCAGCAGCAGCGCGTGTTTCTCGCGCGGGCCTTGGTGCAG
GACGCGGATCTTTACTTCATGGATGAGCCATTTCAAGGTGTGGATGCAGCTACTGAACAAGCAATCGTTACTCTTTTAAA
AACGCTGAAAGGGCGTGGGAAAACGTTGCTTGTTGTGCATCATGATTTGCAGACGGTGGCAGAGTATTTTGACCGCGTGC
TGCTTTTAAATGTTCGCGTCATCGCTGAAGGGGCCGTCGTGTCTGCCTTCACCGAAGAATACGTTCAAAGAGCCTATGGC
GGACGGATTAGTTCCACCCTTTTTCCGAGAGGAAATAAGGAGGATGTGCACGATGCACGCGCTCATGCGTCTGTTCTCTG
A

Protein sequence : 
MAEISATAYAVQVDDLTLAYRQKPVLWDVDVRIPEGVIEAIIGPNGAGKSTLLKAIMGLLPLASGEVRVFGRPFSKERRR
VAYVPQRSAVDWDFPTTVFDVVLMGSYGSLGWILRPGKREKARAREAIEEVGMGAFLDRQISELSGGQQQRVFLARALVQ
DADLYFMDEPFQGVDAATEQAIVTLLKTLKGRGKTLLVVHHDLQTVAEYFDRVLLLNVRVIAEGAVVSAFTEEYVQRAYG
GRISSTLFPRGNKEDVHDARAHASVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0093 AAM75296.1 EF0093 Not tested Not named Protein 9e-38 46
EF0575 NP_814340.1 cationic ABC transporter ATP-binding protein Not tested Not named Protein 1e-37 46
sitB YP_217782.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-40 41
sitB AAD41066.1 SitB Virulence centisome 63 pathogenicity island Protein 9e-41 41
sitB NP_457256.1 Iron transport protein, ATP-binding component Virulence SPI-1 Protein 2e-39 41
sitB NP_806465.1 iron ABC transporter ATP-binding protein Virulence SPI-1 Protein 2e-39 41
sitB NP_461783.1 ATP-binding protein Virulence SPI-1 Protein 1e-40 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TPChic_0164 YP_005631073.1 zinc transport system ATP-binding protein TroB BAC0400 Protein 1e-106 100
TPChic_0164 YP_005631073.1 zinc transport system ATP-binding protein TroB BAC0440 Protein 5e-38 42
TPChic_0164 YP_005631073.1 zinc transport system ATP-binding protein TroB BAC0350 Protein 6e-41 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TPChic_0164 YP_005631073.1 zinc transport system ATP-binding protein TroB VFG0526 Protein 5e-41 41