Gene Information

Name : hlyB (Bint_0625)
Accession : YP_005593834.1
Strain : Brachyspira intermedia PWS/A
Genome accession: NC_017243
Putative virulence/resistance : Virulence
Product : hemolysin B ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 694966 - 697452 bp
Length : 2487 bp
Strand : +
Note : -

DNA sequence :
ATGTTTCAATTTCATTTAACAAGTAAGGCAAAAAAGGTAATAGAATTATATGCCCAGGAAGAGGCTAAAAGATTAAATCA
TGATATGGTTACTCCTGAACATATACTTTTGGGGCTTCTTCATGAATCAGAAGCTTTGGCTACACGTGTTTTATTGAGAT
TGAAAATTGATTTGGACAGACTTAAATTAGAATTAGAATCAGCTATGGTAAAATCTTCAACTACAAAAGTATTTGGAACT
TTACCTACTGCTCCTAGAGTACAGAAACTTATAAGCAGATCTGCTGAAGAGGCTAGAGCTTTAAGCCATAATTATATAGG
TACTGAACATTTACTTCTTGGACTTTTAAGAGAAGAAAGCGGTACAGCTTATAATGTACTAACAAGTATGGGGCTTGAGC
TTACTATATTAAGACAAGAAATATTAAAAATGCTTGGTGTTGCAGGAAGCAATATTTCTTCTATGGAACAGACTACTCAA
GAAGATAATGTTAAAAAAGTTAAAACTCCTACTTTAGATCAATTTGCCAGAGATTTAACTAAAATGGCTAGAGATAAGGC
TTTAGACAGAGTTATAGGCAGAGAAAATGAAGTTATGAGGGTAGTTCAGATTCTATCAAGAAGAAAGAAAAATAATCCTA
TACTTCTTGGAGAGCCTGGGGTAGGTAAAACAGCTATAGTTGAAGGACTTGCTGAAAAGATAGTAGCGGCTGATGTGCCT
GATATACTTCTTAAAAAACGCGTATTAACTTTGGATTTATCTTCTGTTGTTGCTGGTACAAAATACAGAGGTGAATTTGA
AGAGAGAATAAAAAATATAGTTTTAGAAATAAAAAAAGCTAGTAATATTATTATATTCATAGATGAGCTTCATACATTAA
TAGGAGCAGGTGGTGCTGAAGGTGCTTTAGATGCTGCTAATATGTTAAAGCCGGCACTTTCAAGAGGCGAGATTCAATGT
ATTGGTGCTACTACTATAAATGAATATAAAAAATACATAGAAAAAGACGGTGCTTTGGTTAGAAGATTTCAGCCTATCAA
TGTGGAAGAGCCTAGCATAGAAGATACTATAGAAATATTGAATGGTATAAAAGGTAAATACGAAGAACATCATAAAGTAA
AATATACAGATGAAGCTGTAAATGCTGCCGCTGTACTAAGTAAAAGATACATTTTTGAAAGACATTTACCTGATAAAGCT
ATAGATTTAATAGATGAGGCAGGTTCAAGAGCAAGACTTCTTAATATGACAAGACCTCAAGAGTTTAAAGATTTAGATAA
GAAAATAGAAGAACTTAATCAGCAAAAGAAAAATGCTGTTGATAATCAGAATTTTGAAGATGCTGCTAAAATAAGGGATG
AAATTAGTTCTATACAGGAAGAGCTTGCTAAGAAAGAAGAAAAATGGCGTGAAGAAAGAGAAAAGATAGAGACATTCATT
GAAGAAGATGATATAAGACATGTTATATCTGAAATAACTAATATACCTATAAAAAGATTATTAAATTCAGAAAGCAAAAG
ATTAATAGGTATGGAAGAAGAACTACATCAGAAAGTTGTAGGACAGAAAGAGGCTATATCTTCTATATCTAAGGCTATTA
GAAGAAGCAGAGCAGGACTTAAAACATCAAAAAGACCACTTGGTAGTTTTATATTCTTAGGCCCTACTGGTGTTGGTAAA
ACAGCTTTAGCTAAAGTGCTTTCAGAGTTTATGTTTGGAGATAGCGATGCTCTTATCAGAATAGATATGAGTGAGTTTAT
GGAAAAGTTTGCGGTAAGCAGACTTATAGGAGCTCCTCCAGGATATGTTGGTTATGAAGAGGGAGGTGGACTTACTGAAA
AGGTAAGAAGAAAGCCTTATTCTCTTATACTTTTCGATGAGATAGAAAAGGCTCACCCTGATGTTACTAATATACTTTTA
CAGGTGCTTGAAGAAGGTCAGCTTACTGATAATTTTGGAAGAAAAGTTGATTTCTCAAATACTATTATAATTATAACAAG
TAATTTGGGTGCAAGAGATATTATTAAAGGAAGTTCTTTAGGATTTAATGCTGTTGGAAGCGAAAAAGATGCTAATGATA
TTAAAAATTTCGCTTTGGAAGAATTAAAACAGAATTTCAATCCTGAATTTTTAAATAGAATTGATGATATTATAGTGTTC
CATACTCTTAGCAAAGAGGATTTAAAAGATATAATCAATATAATGCTTAAAGAGCTTAATGAGGCTATTAAAGAGAGAAA
TATCGTTATCAATTTAAGCGAAGAAGCTAAGAATTATATTATTGATAAGGGATTTGATAAGAAGTATGGTGCTAGAAGTT
TAAGAAGGGCTATACAGAAAGAGATAGAAGATTATGTGAGTACCGAAATATTGTTTGGTAATATTGAAGATGGTGATACT
ATTAACGTTGATGCTAATGATGGCTCTTTGATATTTTCTTATGAGAAGTCTACTAAGACTGAAAATAAGGAATTATCTAA
AAGTTAG

Protein sequence :
MFQFHLTSKAKKVIELYAQEEAKRLNHDMVTPEHILLGLLHESEALATRVLLRLKIDLDRLKLELESAMVKSSTTKVFGT
LPTAPRVQKLISRSAEEARALSHNYIGTEHLLLGLLREESGTAYNVLTSMGLELTILRQEILKMLGVAGSNISSMEQTTQ
EDNVKKVKTPTLDQFARDLTKMARDKALDRVIGRENEVMRVVQILSRRKKNNPILLGEPGVGKTAIVEGLAEKIVAADVP
DILLKKRVLTLDLSSVVAGTKYRGEFEERIKNIVLEIKKASNIIIFIDELHTLIGAGGAEGALDAANMLKPALSRGEIQC
IGATTINEYKKYIEKDGALVRRFQPINVEEPSIEDTIEILNGIKGKYEEHHKVKYTDEAVNAAAVLSKRYIFERHLPDKA
IDLIDEAGSRARLLNMTRPQEFKDLDKKIEELNQQKKNAVDNQNFEDAAKIRDEISSIQEELAKKEEKWREEREKIETFI
EEDDIRHVISEITNIPIKRLLNSESKRLIGMEEELHQKVVGQKEAISSISKAIRRSRAGLKTSKRPLGSFIFLGPTGVGK
TALAKVLSEFMFGDSDALIRIDMSEFMEKFAVSRLIGAPPGYVGYEEGGGLTEKVRRKPYSLILFDEIEKAHPDVTNILL
QVLEEGQLTDNFGRKVDFSNTIIIITSNLGARDIIKGSSLGFNAVGSEKDANDIKNFALEELKQNFNPEFLNRIDDIIVF
HTLSKEDLKDIINIMLKELNEAIKERNIVINLSEEAKNYIIDKGFDKKYGARSLRRAIQKEIEDYVSTEILFGNIEDGDT
INVDANDGSLIFSYEKSTKTENKELSKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-176 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlyB YP_005593834.1 hemolysin B ATP-binding subunit VFG0079 Protein 0.0 54
hlyB YP_005593834.1 hemolysin B ATP-binding subunit VFG0080 Protein 4e-138 50