Gene Information

Name : clpB (Bint_1230)
Accession : YP_005594429.1
Strain : Brachyspira intermedia PWS/A
Genome accession: NC_017243
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1383300 - 1385879 bp
Length : 2580 bp
Strand : -
Note : -

DNA sequence :
ATGGATTATAACAAATATACAATAAAAGCCCAAGAGGCAGTAAATGAAGCTGCTAATATAGCCAATGGTGAAGACCATAA
CGAAATAAAAAGCGAACATTTACTTTTAGCATTATTGAAACAAGAGGACGGACTTATTCAGCCTTTAGTAGAAAGAATAG
GCGTACCTATAAATACATTGATAGATAAAACTCAAAGATTAGTTGATGAAAACGTAAAGGTTACAGGTGAAAATGTACAG
TTACATCTATCTACTAATGCTGGTAAAGTTTTAGCAAAAGCAGAAAAAGAAGCTAATGCTTTGAAAGATCAATATGTATC
TACAGAGCATATATTTTTAGCACTTGTTGAAGCTGATAACAAAGCAGGAGACATGCTTAGAAAAAGCGGAATAAGTAAAA
AAGAAGTTTTAAGTGCATTAAAAGATTTAAGAAAAGGACAAAGTGTTAATAGCCAAGACCCAGAAGCAAAAATGCAGGCA
CTTGATAAATATTGCCGTGATTTGACTTCATTAGCAGAGGCTGAAAAAATTGACCCTGTTATAGGACGTGATGAAGAAAT
AAGACGTGTTATGCAGGTATTATCAAGAAGAACAAAAAATAACCCTGTACTCATAGGTGAGCCTGGTGTTGGTAAAACTG
CTATTGTTGAAGGACTTGCTAGAAGAATAGTTTCTCAAGATGTACCGGACGGACTTAAAAACAAAAGATTATTAGCTTTG
GATTTAGGTGCTTTGGTTGCTGGTGCTAAATTTAGAGGAGAGTTTGAAGAAAGATTAAAAGCTGTTATTACAGAGATAGA
AAAATCTGAAGGTAACATAATATTATTTATAGATGAGCTTCATACTCTTGTAGGAGCCGGTGCTACTGAAGGTGCAATGG
ATGCTTCTAACCTATTAAAACCTGCATTAGCTAGAGGTGAATTAAGAGCAATAGGTGCAACTACTTTAGATGAATATAGA
AAATATATTGAAAAAGATAAAGCACTTGAAAGAAGATTCCAACAGGTTTATTGTAAAGAACCTAGTGTTGAAGATACTAT
TTCAATATTAAGAGGTTTGAAAGATAAATACGAAGTTCATCATGGTGTTAGAATAAAAGATGATGCATTAGTTGCTGCTG
CTGTTTTATCTAACAGATACATAACTAATAGATTCTTACCTGATAAAGCTATCGACTTGGTAGATGAAGCTGCAAGCCAA
TTGAAAATAGAGATAGATAGTCAGCCTACTGAACTTGATAAAATTGAAAGAAAAATTTTACAGCTTAATATAGAAAAACA
AGCTCTTTCAAAAGAAAATGATGCTGCTTCTAAAGAAAGATTAGAAAAACTTGAAAAAGAATTATCTGAACTTTCTGAAG
AACGTAATGCTATGAAACTTCAATGGGATAATGAAAAAGGAAGAATTGAAGAAACAAGAAAATTAAAAGAAGAACTTGAG
GCTTTAAATATAAAAGAAACTCAGTATACAAGAGAAGGAAATTTAGCAAAAGCTGCTGAAATAAAATATGGTAAAATACC
AGAACTTCAGAAAAAATTAGAAGAAGCTACTAAGGCTATGGAAGAGGCTAAAAACTCTGATAAGAAAAGGCTTTTAAGAG
AAGAAATTTCTGAAGATGATATAGCTAGAGTAATATCTGTATGGACTGGAATACCTGTGAGCAAAATGCTTGCAAGTGAA
AAACAAAAATACTTACAGCTTGAAGAAGTATTACATAAGAGAGTTGTAGGACAAGATGAGGCTATAACTTCAGTTGCTGA
TGCTATTAGAAGAAACAGAGCAGGACTTTCCGATGAAAATAAACCTCTTGGAAGTTTCTTGTTCATAGGACCTACTGGAG
TTGGTAAAACAGAACTTGCTAAAACACTTGCTGATTTCTTATTTAGTGATGAGCATGCTTTAACAAGAATAGATATGAGT
GAGTACATGGAGAAATTCTCTGTTACTAGACTTATAGGAGCCCCTCCGGGATATGTAGGTTATGATGAGGGAGGACAATT
AACAGAAGCAGTTAGAAGGAGACCTTATTCTGTTATACTATTTGATGAGATAGAAAAAGCTCACCCTGATGTATTTAATG
TTTTACTTCAGGTATTAGATGATGGAAGACTTACTGACGGACAAGGAAGAATAGTAGATTTCAAAAATGCTATTATCATA
ATGACAAGTAATTTAGGTTCTGATCTTATTCTTGAAGCTAATGATACTAATGATATCAAAGAAAAGATTCAGGAACTATT
AAAGATGTCATTTAGACCAGAGTTCTTAAACAGAATAGATGAGATAATAACATTTACTAGACTTGACAAAAAATACATTG
CTGAGATAGTAAGAAATCAAATAGCAAGAGTTGCTAACAGACTTAAAGACAGAAGAATAACTTTAGATGTAAGCGATGAA
GCTATAGACTATATTGCTGATATTGGTTATGATCCTCAGTTTGGAGCAAGACCATTGAAAAGAGCTATACAAAACTTTAT
AGAAAATCCTCTAGCTAAAGAAATGCTAGCAGGCAAATATTTAGAAGGAGATACTATAAAGGTGAAAAAATCAGGAGATG
GTTTAGTATTTGAAAAATAA

Protein sequence :
MDYNKYTIKAQEAVNEAANIANGEDHNEIKSEHLLLALLKQEDGLIQPLVERIGVPINTLIDKTQRLVDENVKVTGENVQ
LHLSTNAGKVLAKAEKEANALKDQYVSTEHIFLALVEADNKAGDMLRKSGISKKEVLSALKDLRKGQSVNSQDPEAKMQA
LDKYCRDLTSLAEAEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSQDVPDGLKNKRLLAL
DLGALVAGAKFRGEFEERLKAVITEIEKSEGNIILFIDELHTLVGAGATEGAMDASNLLKPALARGELRAIGATTLDEYR
KYIEKDKALERRFQQVYCKEPSVEDTISILRGLKDKYEVHHGVRIKDDALVAAAVLSNRYITNRFLPDKAIDLVDEAASQ
LKIEIDSQPTELDKIERKILQLNIEKQALSKENDAASKERLEKLEKELSELSEERNAMKLQWDNEKGRIEETRKLKEELE
ALNIKETQYTREGNLAKAAEIKYGKIPELQKKLEEATKAMEEAKNSDKKRLLREEISEDDIARVISVWTGIPVSKMLASE
KQKYLQLEEVLHKRVVGQDEAITSVADAIRRNRAGLSDENKPLGSFLFIGPTGVGKTELAKTLADFLFSDEHALTRIDMS
EYMEKFSVTRLIGAPPGYVGYDEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRIVDFKNAIII
MTSNLGSDLILEANDTNDIKEKIQELLKMSFRPEFLNRIDEIITFTRLDKKYIAEIVRNQIARVANRLKDRRITLDVSDE
AIDYIADIGYDPQFGARPLKRAIQNFIENPLAKEMLAGKYLEGDTIKVKKSGDGLVFEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-99 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-99 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-99 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_005594429.1 ATP-dependent Clp protease, ATP-binding subunit ClpB VFG2084 Protein 2e-106 42