Gene Information

Name : clpC (HMPREF9228_0514)
Accession : YP_005582405.1
Strain : Bifidobacterium breve ACS-071-V-Sch8b
Genome accession: NC_017218
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 608498 - 611089 bp
Length : 2592 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAACGGTTTACCGACCGTGCACGGCGCGTGATCGTGTTGGCGCAGGAAGAGGCGAGGACTCTCCAGCACAACTA
CATCGGCACCGAACACCTGCTGCTCGGCCTGATCCGAGAGGGTGAGGGCGTGGCCGCCAAGGCACTCGCCTCGAAGGGCG
TGGAGTTGGACGCCACCCGCAAGCAGGTCGAAGAGATGATCGGCAAGGGCAACGCGGCCCCGAACGGGCACATCCCCTTT
ACCCCGCATGCCAAGCAGGTGCTGGAGTTCTCGTTGCGTGAGGCTTTGCAGTTGGGCCACAGCTACATCGGCACTGAGCA
TATTCTGCTCGGCTTGATTCGCGAGGGTGAAGGCGTGGGCACTCAGGTGCTCATCAAGATGGACGTTGATTTGGGCGAGC
TGCGCAGCGCAACCATCGATATGATTCGCGGCAACTCCGGCACCTCCACTGACGGCAAGGGCGATTTGGCCAACGCCGGT
GGCGTGGCGGACAAGCAGAACAAGTCCGGTTCCGCCATTCTCGACCAGTTCGGCCGCAACCTGACCGCCGAAGCCGCCGA
GGGCAAGTTGGATCCGGTCATCGGCCGTACTAACGAGATCGAGCGCGTTATGGTCGTGCTCTCCCGCCGCACCAAGAACA
ACCCGGTGCTGATCGGCGAGCCTGGCGTGGGCAAGACCGCTGTGGTCGAAGGACTGGCCCAGAAGATTCAGGCCGGCGAT
GTGCCGGAGACCTTGAAAGGCAAGCAGGTCTACTCGCTGGATCTTGGTTCCATGGTGGCCGGTTCCCGTTACCGTGGTGA
TTTCGAGGAGCGTCTGAAGAAGGTCCTGAAGGAAATCAAGACCCGTGGCGACATCGTGCTGTTCATCGACGAGATCCACA
CCATCGTGGGTGCCGGCTCTGCCGACGGCGCACTGGGTGCCTCCGATATGTTGAAGCCGATGCTGGCCCGTGGCGAGCTG
CAGACCATCGGCGCCACCACCACCGACGAGTACCGCAAGTACATCGAGAAGGACGCGGCGCTGGAACGCCGATTCCAGCC
CATCCAGGTGCATGAGCCGACCATCGCCGAGACCATTGAAATCTTGAAGGGCCTGCGTTCTCGCTACGAGAACCACCATC
ACGTGACCATCACCGATGGTGCGTTGCAGTCTGCCGCAGAGCTTTCCAGCCGCTATATTCAGGATCGCAACCTGCCGGAT
AAGGCCATCGATTTGATCGACGAGGCCGGTGCCCGCCTGCGCATCAAGCGTCTGACTGCACCGCCCGAGCTCAAGGAGCT
TGACGACAAGATCGCCAAGATCGCCGCCGACAAGGACGAGGCCATCAAGGGCCAGGACTTCGAGAAGGCCGCCGAACTGC
GCGACAACCAAGAGAAGTTGGAAGCCGAGCGCAAGGCGAAGGAAGATTCCTGGCGCGAAGGCGAGTCCGACGTCAAGATG
GTCGTGGATGAGGACGTGATCGCCGAGGTCATCAGCTCCACCACCGGTATTCCGGTGTTCAAGCTGACCCAGGCTGAGTC
CAAGAAGCTGCTCAACATGGAAGCCGAGCTGCACAAGCGCATTATCGGCCAGGATGAGGCGGTGTCCGCCCTGTCCCGCT
CCATCCGCCGTACCCGCGTGGGCCTGAAGGACCCGAAGCGCCCGTCCGGTTCGTTCATCTTTGCCGGCCCCACCGGCGTG
GGCAAGACCGAGCTGGCCAAGACGCTGGCCGAGTTCCTGTTCGACGATGAGGATGCGCTGATTCGCGTCGATATGTCCGA
GTTCTCCGAGAAGTATGCGGCATCGCGTCTCTTTGGTGCGCCTCCGGGATACGTCGGTTATGAGGAGGGCGGCGAGCTCA
CCGAGAAGGTGCGCCGCAAGCCGTTCTCCGTGGTGCTGTTCGATGAGATCGAGAAGGCTCACCCGGATATCTTCAACACC
TTGCTGCAGGTGCTGGATGATGGCCACTTGACCGATGGTCAGGGCCGTAAGGTGGACTTCAAGAACACCATCATCATCCT
GACCACCAACCTCGGTACGCGCGACATCGCCAAGGCCGCCAACACGGGCTTCAACCTGGGCGCCAACAGCGAATCCAGCT
ACCAGCGTATGAAGGATCAGGTCAGCTCCGAGCTCAAGCAGCAGTTCCGTCCGGAGTTCCTGAACCGTTTGGACGACATC
ATCGTCTTCAAGCAGCTCACCGAGCCGCAGGTGCGTCAGATTGTGGATCTGGATGTCAAGCAGCTCAACGATCGTCTGTT
CGACCGCCACATGTCGCTCGAACTTACCGACGCCGCCAAGGATCTGCTCGCGCAGAAGGGCTTTGACCCGCTGCTCGGCG
CTCGTCCGCTGCGCCGTGTGATTCAGCGCGACATCGAGGACGCCATCTCCGAGAAGATCCTGATGGGCGACCTCGAAGAC
GGTCAGAAGGTTATCGTCGACGCCGAGGGCGAAGGTCTGCTGGGTGAGTTCACCTTCAAGGGCGAGACCTTCGAACAGCC
TGAGGCCGAGACGGGGGATTCTGTTTCTGCGGTCGATGGAGAGGCGGGATCTCCCGCGGAAACGGAGTCCGAGCCGTCGA
ACGATGGTCCCGTTTCCAACGATGCCGAGTAG

Protein sequence :
MFERFTDRARRVIVLAQEEARTLQHNYIGTEHLLLGLIREGEGVAAKALASKGVELDATRKQVEEMIGKGNAAPNGHIPF
TPHAKQVLEFSLREALQLGHSYIGTEHILLGLIREGEGVGTQVLIKMDVDLGELRSATIDMIRGNSGTSTDGKGDLANAG
GVADKQNKSGSAILDQFGRNLTAEAAEGKLDPVIGRTNEIERVMVVLSRRTKNNPVLIGEPGVGKTAVVEGLAQKIQAGD
VPETLKGKQVYSLDLGSMVAGSRYRGDFEERLKKVLKEIKTRGDIVLFIDEIHTIVGAGSADGALGASDMLKPMLARGEL
QTIGATTTDEYRKYIEKDAALERRFQPIQVHEPTIAETIEILKGLRSRYENHHHVTITDGALQSAAELSSRYIQDRNLPD
KAIDLIDEAGARLRIKRLTAPPELKELDDKIAKIAADKDEAIKGQDFEKAAELRDNQEKLEAERKAKEDSWREGESDVKM
VVDEDVIAEVISSTTGIPVFKLTQAESKKLLNMEAELHKRIIGQDEAVSALSRSIRRTRVGLKDPKRPSGSFIFAGPTGV
GKTELAKTLAEFLFDDEDALIRVDMSEFSEKYAASRLFGAPPGYVGYEEGGELTEKVRRKPFSVVLFDEIEKAHPDIFNT
LLQVLDDGHLTDGQGRKVDFKNTIIILTTNLGTRDIAKAANTGFNLGANSESSYQRMKDQVSSELKQQFRPEFLNRLDDI
IVFKQLTEPQVRQIVDLDVKQLNDRLFDRHMSLELTDAAKDLLAQKGFDPLLGARPLRRVIQRDIEDAISEKILMGDLED
GQKVIVDAEGEGLLGEFTFKGETFEQPEAETGDSVSAVDGEAGSPAETESEPSNDGPVSNDAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_005582405.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 57
clpC YP_005582405.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 2e-136 51