Gene Information

Name : pyk (HMPREF9228_1101)
Accession : YP_005582931.1
Strain : Bifidobacterium breve ACS-071-V-Sch8b
Genome accession: NC_017218
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1258145 - 1259587 bp
Length : 1443 bp
Strand : -
Note : -

DNA sequence : 
ATGCGTAAAGCCAAGATCGTAGACACCATCGGTCCTTCCACCGAGGATTACGACAACCTTCTCAAGCTCGTCGAAGCCGG
TATGGACGTTGCTCGTCTGAACCGCTCCCACGGCACCCCCGAAGATCACCTCAACGTGTACAACAACGTGCGCAAGGCCA
GCGAGGCCACCGGCCGCAACGTGGCCGCTCTCGTTGATCTGCAGGGCCCGAAGATTCGCTGCGGTTGGTTCAAGAAGAAC
GCCGAGGGCGAGGACAAGGTCCAGCTGACGCTCGGCCAGGAATTCATCATCACCACCGACGACGTTGAGGGTGACGAGCA
CATCACCTCCACCACGTTCAAGGGCCTGCCGGGTGACTGCCACCCGGGCGACCCGATTCTGATCGATGACGGCAAGGTTC
GCCTTGAGGTCACCAAGGTCGAGGGCAACAACGTGCACACCAAGGTTGTCGTCGCTGGCCCCGTGTCCTCCCACAAGGGC
ATCAACCTGCCGGGCGTCGCCGTCTCTCTGCCGGCTCTGACTGAGAAGGATGAGGCCGACCTGCGCTGGGCCATCCGCAC
CGGTGCCGACATCATCGCCATGTCCTTCGTGCGTTTCGCCACCGACATCGACCGCGCCCACGAGATTATGGATGAGGAAG
GCCGTCGTATTCCGATCGTCGCCAAGATCGAGAAGCCGCAGGCTCTGGAGAACCTCGAAGAGATCGTCAAGACCTTCGAC
GGCGTCATGGCCGCCCGCGGCGACATGGCTGTTGAGTGCCCGCTGGAAGAGGTCCCGCTGGCCACCAAGCGCATCATCGA
GCTGGCCCGCCAGTACGCCAAGCCGGTCATCGTGGCCACCGAAGTCCTCGGCTCCATGGTGAACTCCCCGGTCCCGACCC
GTGCAGAGGCCTCCGACTGCGCCAACGCCGTTCTCGACGGCTCCGACGCTACCATGACCTCCAACGAGACCGCCGTTGGT
AAGTACCCGGATGTGACCGTGGCTACCATGGCCCGTATTTCCGCTTACGCCACCGACCACGGCTTCGACCGTATCCCGGA
GCTCAAGAACCTTGACATGTCTTCCACCGGCGCTGTTTCCTCCGCTGCTGTGGATCTGGCTGACAAGCTCAACGCCAAGG
CCATCGTTGCTTACACCCAGACCGGTTCCACCGTGCACCGCGTGTCCCGCGAGCGTCCGGCCGCCCCGATCTACGGCCTG
ACCAACAACGAGCACACCTACCACTGGCTGGCTCTGTCTTGGGGCACCGAAGCCTTCCTGCTCAAGGAGGACTACCACGA
CAAGTCCCGCAAGGACCTCATGATCTTCACCGACAAGGTCCTCAAGGACGCCGGCAAGGTTGTTGACGGCGACAAGATCG
TCATTCTGAGCTCCGCTCAGGGCGATCACCAGCCGGGCCGCACCGACTCCATCTACGTGCACACTGTTGGCGCTTGCGAC
TGA

Protein sequence : 
MRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLNVYNNVRKASEATGRNVAALVDLQGPKIRCGWFKKN
AEGEDKVQLTLGQEFIITTDDVEGDEHITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKVEGNNVHTKVVVAGPVSSHKG
INLPGVAVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMDEEGRRIPIVAKIEKPQALENLEEIVKTFD
GVMAARGDMAVECPLEEVPLATKRIIELARQYAKPVIVATEVLGSMVNSPVPTRAEASDCANAVLDGSDATMTSNETAVG
KYPDVTVATMARISAYATDHGFDRIPELKNLDMSSTGAVSSAAVDLADKLNAKAIVAYTQTGSTVHRVSRERPAAPIYGL
TNNEHTYHWLALSWGTEAFLLKEDYHDKSRKDLMIFTDKVLKDAGKVVDGDKIVILSSAQGDHQPGRTDSIYVHTVGACD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-64 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-64 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-64 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-63 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_005582931.1 pyruvate kinase VFG0479 Protein 3e-64 44