Gene Information

Name : BALAC2494_00466 (BALAC2494_00466)
Accession : YP_005577843.1
Strain : Bifidobacterium animalis CNCM I-2494
Genome accession: NC_017215
Putative virulence/resistance : Virulence
Product : Negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 781216 - 783804 bp
Length : 2589 bp
Strand : +
Note : TlyB; Hemolysin

DNA sequence :
GTGGTTTGGAATTGTATTGATTATGGAAGGACAAGCATGTTCGAACGGTTTACCGACCGTGCGCGCCGGGTCATCGTGCT
CGCGCAGGAAGAGGCTCGTGCCCTCCAGCACAATTACATCGGCACCGAGCATCTGCTGCTTGGGCTGATTCGTGAGGGAG
ATGGCGTGGCCGCCAAGGCTCTCGAAGCCAAAGGCGTGACGTTGGAAGACACCCGCAAGCAGGTCGAGGAGATGATCGGC
AAGGGCACCGCGGCTCCGACAGGCCACATTCCCTTCACTCCGCATGCCAAGCAGGTGCTGGAGCTCTCGCTGCGTGAAGC
GTTGCAGCTGGGGCATAGCTACATCGGAACCGAACATATTCTGTTGGGCCTCATTCGTGAGGGTGAGGGCGTGGGCACCC
AGGTGCTCATCAAGATGGACGTCGATCTTTCCGACCTGCGCAGCACCACGATCGACATGATTCGCGGCAACTCCGGCAAC
GGTGAGGGAGACAAGGGCGACATGGCCAACGCGGGTTCCGTGCAGGACAAGCGCAGCCAGAGCGGTTCCGCCATACTGGA
TCAGTTCGGGCGCAACCTGACGGCCGAGGCGAAGGACGGCAAACTCGACCCGGTCATCGGCCGCAGCACTGAGATCGAAC
GCGTCATGGTGGTGCTTTCGCGCCGTACGAAGAACAATCCGGTGCTGATTGGTGAGCCGGGCGTCGGCAAGACGGCGGTG
GTCGAGGGACTTGCGCAGAAGATCGTCGCCGGTGATGTGCCGGAGACGCTCAAGGACAAGCAGGTGTATTCGCTCGATCT
GGGTTCCATGGTCGCGGGATCGCGGTATCGCGGTGATTTTGAGGAACGCTTGAAGAAGGTGCTCAAGGAGATCAAGACCC
GCGGCGACATCGTGCTGTTCATCGATGAGATTCATACGATTGTGGGAGCTGGCTCCGCGGACGGGGCTCTCGGTGCCTCC
GATATGCTCAAACCGATGCTGGCGCGCGGCGAGCTCCAGACCATTGGCGCCACGACCACCGACGAGTACCGCAAGTACAT
CGAGAAGGACGCCGCCTTGGAACGCCGATTCCAGCCGATCCAGGTGTCGGAACCGTCGATTGCCGAGACGATTGAGATCC
TCAAGGGGTTGCGTGCACGCTACGAGAATCACCACCATGTGACGATCACCGATGGTGCACTGCAGTCTGCCGCAGAACTT
TCGGCACGGTACATTCAGGACCGCAACCTTCCCGATAAGGCAATCGATTTGATCGATGAGGCGGGTGCGCGTCTGCGCAT
CAAGCGCCTTACCGCGCCTCCGGAGCTCAAGGAGCTTGACAACCGCATTGCGCGCATCGCCAAGGAGAAGGACCAGACGA
TCAAGGACCAGCAGTTCGAGAAGGCCGCCGAGCTTCGCGACAAGCAGGAGAAGCTTGAGGCTGAGCGCAAAGAGAAAGAG
AAGTCCTGGCGTGAGGGCGAATCCGACGTCCGTATGGTCGTCGATGAGGATGTGATCGCCGAGGTGATCTCGCAGAGCAC
GGGCATTCCGGTGTTCAAGCTCACCCAGGCGGAATCCAAGAAGCTCATGTCGATGGAGAAGGAGCTGCATAAGCGCATCA
TCGGTCAGGATGAGGCCGTCTCTGCGCTGTCGCGCTCCATCCGCCGTACACGTGTGGGACTCAAGGACCCGAAGCGTCCG
GCGGGATCGTTCATCTTCGCCGGCCCCACCGGCGTGGGCAAGACCGAACTTGCCAAGGCTCTCGCTCAGTTCCTGTTCGA
CGATGAGGATGCGCTCATTCGCGTCGACATGTCGGAGTTCTCAGAAAAGTACGCGGCTTCGCGTCTGTTCGGAGCCCCTC
CGGGATATGTCGGTTATGAGGAGGGTGGTGAGCTCACCGAGAAGGTGCGCCGCAAGCCGTTCTCCGTCGTGCTGTTCGAT
GAGATCGAAAAGGCCCATCCCGACATCTTCAACACATTGCTGCAGGTGTTGGATGACGGCCACTTGACCGATGGCCAGGG
GCGCAAAGTGGACTTCAAGAACACCATCATCATTTTGACGACCAATCTCGGCACGCGTGACATCGCGAAGACCGCCAATA
CAGGCTTCACGATGGGGGGCAACACCGAATCGAGCTATCAGCGCATGAAGGACCAGGTGTCGAGCGAGCTCAAGCAGCAG
TTCCGCCCCGAGTTCCTCAACCGTTTGGATGACATCATCGTGTTCCGCCAGCTCACCGAACCGCAGGTGCGCCAGATCGT
CGATCTCGATGTCACGAAGATCAACGATCGTCTGTTCGAACGTCATATGGAGCTCGACCTGACCGATAAGGCCAAGGATT
TGCTCGCGGAAAAGGGCTTCGACCCGTTGCTTGGTGCCCGACCGCTACGTCGTGTGATTCAGCGTGATATCGAGGACACC
ATTTCCGAAAAGATTCTCATGGGCGATCTGCACGACAACGAACGTGTGATCGTCGATGCCGAAGGTGATGGCATTCTCGG
GGAGTTCACGTTCCGCGGCGAGCCTTTCGAGCTCCCGGCGGCAGGCGAAGGGGACGAGTCGAAGGATGTCGTGCCCGAAC
CTGCGGCTGCGGCGAGTGAGGCCGAATAA

Protein sequence :
MVWNCIDYGRTSMFERFTDRARRVIVLAQEEARALQHNYIGTEHLLLGLIREGDGVAAKALEAKGVTLEDTRKQVEEMIG
KGTAAPTGHIPFTPHAKQVLELSLREALQLGHSYIGTEHILLGLIREGEGVGTQVLIKMDVDLSDLRSTTIDMIRGNSGN
GEGDKGDMANAGSVQDKRSQSGSAILDQFGRNLTAEAKDGKLDPVIGRSTEIERVMVVLSRRTKNNPVLIGEPGVGKTAV
VEGLAQKIVAGDVPETLKDKQVYSLDLGSMVAGSRYRGDFEERLKKVLKEIKTRGDIVLFIDEIHTIVGAGSADGALGAS
DMLKPMLARGELQTIGATTTDEYRKYIEKDAALERRFQPIQVSEPSIAETIEILKGLRARYENHHHVTITDGALQSAAEL
SARYIQDRNLPDKAIDLIDEAGARLRIKRLTAPPELKELDNRIARIAKEKDQTIKDQQFEKAAELRDKQEKLEAERKEKE
KSWREGESDVRMVVDEDVIAEVISQSTGIPVFKLTQAESKKLMSMEKELHKRIIGQDEAVSALSRSIRRTRVGLKDPKRP
AGSFIFAGPTGVGKTELAKALAQFLFDDEDALIRVDMSEFSEKYAASRLFGAPPGYVGYEEGGELTEKVRRKPFSVVLFD
EIEKAHPDIFNTLLQVLDDGHLTDGQGRKVDFKNTIIILTTNLGTRDIAKTANTGFTMGGNTESSYQRMKDQVSSELKQQ
FRPEFLNRLDDIIVFRQLTEPQVRQIVDLDVTKINDRLFERHMELDLTDKAKDLLAEKGFDPLLGARPLRRVIQRDIEDT
ISEKILMGDLHDNERVIVDAEGDGILGEFTFRGEPFELPAAGEGDESKDVVPEPAAAASEAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BALAC2494_00466 YP_005577843.1 Negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 57
BALAC2494_00466 YP_005577843.1 Negative regulator of genetic competence clpC/mecB VFG0080 Protein 7e-140 50