Gene Information

Name : dhbE (BAMTA208_15890)
Accession : YP_005542824.1
Strain : Bacillus amyloliquefaciens TA208
Genome accession: NC_017188
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3028512 - 3030137 bp
Length : 1626 bp
Strand : -
Note : COG1021 Peptide arylation enzymes

DNA sequence :
GTGCTGACAGGATTTACGCCATGGCCGGAAGAATGGGCTGACAAATACCGCAAAGACGGCTGCTGGAAGGGTGAAACTTT
CGGAGGAATTCTGAAGGAGCGCGCGGCTTTATATGGAAATCAAACTGCCGTGACGTATAAAGATGTACATTGGACCTACA
AAGAATTAGATGAAAGGGCCGATCGTTTAGCGGCGGGACTGCACAAGCTCGGGATTCAAAAGGAAGACCGTGTTGTCGTT
CAGCTGCCGAATATCGCTGAGTTTTTTGAAGTGATATTCGCCCTGTTCCGGCTCGGAGCGCTCCCCGTTTTCGCGTTGCC
TTCTCATAGAAGCAGTGAGATTACTTATTTTTGCGAGTTTGCAGAGGCGAAAGCATACATCATTCCTGATACGCATTCAG
GCTTTGATTACAGAGAGCTTGCCAGACAGGTGAAAGATAAACTTCCGGCTTTGGCGCATGTCATTGTAGCCGGTGAGGCT
GAAGAGTTTCTGGAACTGAGCAGCCTGCACAGAGAGCCTGTTCAGCTGGAAGACGTAAGCTCGGCGGAAGTCGCTTTTTT
ACAGCTTTCAGGAGGCAGTACGGGGCTGTCCAAGCTGATTCCGAGGACACATGATGATTACATATACAGCTTGCGCCTCA
GCGCGGAAATATGCGGCTTGGATCATCACAGCGTTTATTTAGCTGCTTTGCCGACAGCGCATAATTATCCGCTCAGTTCA
CCCGGTGTGCTGGGAACTTTATATGCCGGGGGCCGGGTTGTTCTGTCACCGACGCCGAGTCCGGATGACTGCTTCCCGTT
AATTGAAAAAGAACGTGTCACGATTACAGCGCTCGTCCCGCCGCTCGCCATGGTATGGATGGAAGCATCCGGATCGCGAA
GTGATGATTTATCAAGCCTTCAAGTGCTGCAGGTGGGAGGCGCCAAATTCAGCGCTGAAGCGGCCCGCCGCGTGAAGAGC
GCTTTCGGATGCACCCTTCAGCAGGTTTTCGGAATGGCGGAAGGATTAGTGAATTATACGAGACTGGATGATCCTGAGGA
GATTATTATCAATACGCAAGGCAGACCGATGTCACCATTTGATGAAGTGAGGGTTTTAAACGATGACGGGCGGGATGCGG
CTCCCGGCGAAACCGGACATTTGTTTACACGCGGTCCTTACACGATTCGCGGATATTATAAAGCGCCTGAGCATAATGCG
AGATCTTTCACAGCCGACGGCTTTTATCAAACCGGCGATATCGTCAAACTGACGGAAGACGGGTATATTGTCGTCGAAGG
ACGGGCGAAAGATCAAATCAATCGGGGAGGCGAAAAGATTGCCGCTGAAGAGGTGGAAAATCACCTTCTCGCCCACCCTG
CCGTTCATGATGCGGCCATGGTTTCAATGCCGGATGATTTTCTCGGAGAGCGGTCCTGTGTGTTCGTCATTCCGAAAGGA
GAAGCGCCGAAACCGGGAGAGCTGAAAGCATTTTTGCGTGAGCGCGGACTGGCGGCCTATAAAATTCCCGACCGGATTGA
ATTTACCGCTTCTTTCCCGAAAACCGGCGTCGGCAAGGTCAGCAAAAAGGATCTTCGCGAAACGATCGCCAAAAAATTGA
AGCCTGCTGAAATCAAACAATCATAA

Protein sequence :
MLTGFTPWPEEWADKYRKDGCWKGETFGGILKERAALYGNQTAVTYKDVHWTYKELDERADRLAAGLHKLGIQKEDRVVV
QLPNIAEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAKAYIIPDTHSGFDYRELARQVKDKLPALAHVIVAGEA
EEFLELSSLHREPVQLEDVSSAEVAFLQLSGGSTGLSKLIPRTHDDYIYSLRLSAEICGLDHHSVYLAALPTAHNYPLSS
PGVLGTLYAGGRVVLSPTPSPDDCFPLIEKERVTITALVPPLAMVWMEASGSRSDDLSSLQVLQVGGAKFSAEAARRVKS
AFGCTLQQVFGMAEGLVNYTRLDDPEEIIINTQGRPMSPFDEVRVLNDDGRDAAPGETGHLFTRGPYTIRGYYKAPEHNA
RSFTADGFYQTGDIVKLTEDGYIVVEGRAKDQINRGGEKIAAEEVENHLLAHPAVHDAAMVSMPDDFLGERSCVFVIPKG
EAPKPGELKAFLRERGLAAYKIPDRIEFTASFPKTGVGKVSKKDLRETIAKKLKPAEIKQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-120 51
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-120 51
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-120 51
ybtE CAA21394.1 - Virulence HPI Protein 1e-120 51
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-121 51
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-120 51
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-120 51
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-120 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-120 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_005542824.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-142 55
dhbE YP_005542824.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-117 48
dhbE YP_005542824.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 7e-113 45