Gene Information

Name : mccB (BAMTA208_13370)
Accession : YP_005542328.1
Strain : Bacillus amyloliquefaciens TA208
Genome accession: NC_017188
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 2546780 - 2547922 bp
Length : 1143 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGAAGAAAAAAACGCTGATGGTGCACGGAGGAATTACGGGAGATGAAAAAACCGGAGCGGTTTCCGTACCGATTTATCA
AGTAAGCACATACCAGCAGCCGAAAGCGGGCGAGCACACGGGCTATGAATACTCAAGAACGGCCAATCCGACGCGGACGG
CTCTTGAAAGTTTAATTACAGAGCTTGAAGGCGGCGCGGCGGGATATGCGTTCGGCTCAGGAATGGCTGCGATTACGGCC
GTCATGATGCTGTTTGACAGCGGGGATCATGTTATTTTGACGGACGATGTATACGGCGGCACTTACCGGGTGATGACAGG
TGTGCTGAACCGTTTCGGCATTGAAGCGGATTTTGTGGATACGAGCAGTAAAGAAAAAGTCCAAAAAGCCATCCGTCCGA
ATACGAAAGCCATTTATATCGAAACACCGACAAATCCGCTTTTGAAAGTGACTGATCTCAAATTGATGTCTGACATCGCA
AAAGAAGCGGGCGTATTGCTCATTGTCGACAATACGTTTTATACGCCGTATTTCCAGCAGCCGCTCAGCTTCGGCGCTGA
CATCGTGCTGCACAGTGCGACAAAATATCTTGGCGGCCACAGTGATGTCGTCGGCGGCTTAGTCGTAACGGCTGATAAAG
AGCTCGGCGAAAAGCTTCATTATGTGCAAAACTCAACGGGCGGCGTTTTAGGACCGCAGGATTCATGGCTGTTGATGAGA
GGGATTAAAACGCTTGGACTCAGAATGGACGCCATCAATCACAGCGCCGGAAAGATCGCCGAGCTGCTTGAAGCGCATGA
TGCCGTTCAGACGCTCTACTATCCGGGATCACCGAAACACCCGGGCCATGAGCTGACAAAAGCGCAAAGCTCCGGTTTCG
GCGGAATGATTTCCTTTGATATCGGCAGCAGCGAACGTGTCGACGCATTTTTAGAAAAATTGAACCTGTTTACGATCGCG
GAAAGCTTAGGAGCGGTTGAAAGCCTAATCTCCGTGCCGTCCAGAATGACACACGCTTCGATTCCGCGCGACCGCCGGCT
TGCACTCGGCATTACGGACGGGCTCGTACGGATCTCAGTCGGTATTGAGGACACTGAGGATTTAACGGCGGATGTGAAAC
AGGCGCTTGATTCACTTTTATAA

Protein sequence :
MKKKTLMVHGGITGDEKTGAVSVPIYQVSTYQQPKAGEHTGYEYSRTANPTRTALESLITELEGGAAGYAFGSGMAAITA
VMMLFDSGDHVILTDDVYGGTYRVMTGVLNRFGIEADFVDTSSKEKVQKAIRPNTKAIYIETPTNPLLKVTDLKLMSDIA
KEAGVLLIVDNTFYTPYFQQPLSFGADIVLHSATKYLGGHSDVVGGLVVTADKELGEKLHYVQNSTGGVLGPQDSWLLMR
GIKTLGLRMDAINHSAGKIAELLEAHDAVQTLYYPGSPKHPGHELTKAQSSGFGGMISFDIGSSERVDAFLEKLNLFTIA
ESLGAVESLISVPSRMTHASIPRDRRLALGITDGLVRISVGIEDTEDLTADVKQALDSLL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-112 62
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-110 61
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-74 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mccB YP_005542328.1 cystathionine beta-lyase BAC0207 Protein 6e-66 43