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Name : RAM_04495 (RAM_04495) Accession : YP_005528848.1 Strain : Amycolatopsis mediterranei S699 Genome accession: NC_017186 Putative virulence/resistance : Virulence Product : NAD-dependent aldehyde dehydrogenase Function : - COG functional category : - COG ID : - EC number : - Position : 940761 - 942194 bp Length : 1434 bp Strand : - Note : COG1012 NAD-dependent aldehyde dehydrogenases DNA sequence : ATGCCTGTTTTCGAGTACGCACCGGCGCCGGAATCGCGCGCCATCGCGAACCTGAAGGACGCCTACAAGCCGTTCGTCAA CGGCGAGTTCGTCGACGGCTCGGGTGAGCCGCTGAAGACGATCAACCCGGCCACCGAGGAGGTCCTGGCCGAGGTCGGCA CCGCGTCGAAGTCCGATGTGGACATCGCGGTCAAGGCCGCGCGCAAGGCTTTCACGGGTGTCTGGTCGAAGATGCCGGGC ACCGAGCGCGCGAAGTACCTCTTCCGGATCGCGCGGCTGATCCAGGAGCGTTCGCGCGAGCTGGCCGTGCTGGAGAGCCT CGACAACGGCAAGCCGATCAAGGAGTCGCGCGACTCCGACGTCCCGACGGCGGCCGCGCACTTCTTCTACCACGCGGGCT GGGCCGACAAGCTCGACTACGCGGGCTACGGCCCTTCGCCGCGCCCCCTGGGTGTCGCGGGCCAGATCATCCCGTGGAAC TTCCCGCTGCTGATGCTGGCCTGGAAGATCGCCCCGGCGCTGGCCACCGGCAACACCGTGGTGCTGAAGCCCGCCGAGAC GACACCGCTGACCGCGCTGGTGTTCGCCGAGATCTGCCAGCAGGCCGAGCTGCCGCCGGGCGTGGTGAACATCCTCCCGG GCGCGGGCGACATCGGCGCGTCCATCGTGGAGCACGGGGACATCGACAAGATCGCCTTCACCGGCTCGACCGAGGTCGGC AAGGCGATCCAGCGCCAGGTCGCGGGCACGCCGAAGAAGCTGACGCTGGAACTGGGCGGCAAGGCGGCGAACATCGTCTT CGAGGACGCGCCGCTCGACCAGGCCGTCGAAGGCATCGTCAACGGCATCTTCTTCAACCAGGGGCACGTCTGCTGCGCGG GCTCGCGCCTGCTGGTGCAGGAGTCCATCGCCGAAGAGGTGCTGGAGAAGCTGCGCTACCGCGTCTCGACGTTGCGCATC GGCGACCCGCTGGACAAGAACACCGACATCGGCGCGATCAACTCCGCCGAGCAGCTGGCCAAGATCCGCGGGCTCGTCGA AGCCGGGGACGCCGAGGGCGCGCAGCGCTGGACCAGCCCGTGCCCGGTCCCGGACCGCGGGTTCTTCTTCGCCCCGACGG TGTTCGCGAACGTCCACCAGTCGATGCGGATCGCCCGCGAGGAGATCTTCGGCCCGGTGCTGTCGGTGCTGACGTTCCGC ACGCCGGACGAGGCCGTCGCGAAGGCGAACAACACACCGTACGGGCTTTCGGCGGGCATCTGGACCGAAAAGGGCTCCCG GATCCTGTGGATGGCGAACCAGCTGCGCGCCGGCGTGGTCTGGGCCAACACCTTCAACCGCTTCGACCCCACCGCCCCCT TCGGCGGCTACCAGGAATCCGGCTTCGGGCGCGAAGGCGGCCGCACCGGGCTGGAGGCGTACCTGAATGTCTGA Protein sequence : MPVFEYAPAPESRAIANLKDAYKPFVNGEFVDGSGEPLKTINPATEEVLAEVGTASKSDVDIAVKAARKAFTGVWSKMPG TERAKYLFRIARLIQERSRELAVLESLDNGKPIKESRDSDVPTAAAHFFYHAGWADKLDYAGYGPSPRPLGVAGQIIPWN FPLLMLAWKIAPALATGNTVVLKPAETTPLTALVFAEICQQAELPPGVVNILPGAGDIGASIVEHGDIDKIAFTGSTEVG KAIQRQVAGTPKKLTLELGGKAANIVFEDAPLDQAVEGIVNGIFFNQGHVCCAGSRLLVQESIAEEVLEKLRYRVSTLRI GDPLDKNTDIGAINSAEQLAKIRGLVEAGDAEGAQRWTSPCPVPDRGFFFAPTVFANVHQSMRIAREEIFGPVLSVLTFR TPDEAVAKANNTPYGLSAGIWTEKGSRILWMANQLRAGVVWANTFNRFDPTAPFGGYQESGFGREGGRTGLEAYLNV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| aldA | ACK75588.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 9e-50 | 43 |
| aldA | ACK75577.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 7e-50 | 43 |
| aldA | ACK75580.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 1e-49 | 43 |
| aldA | ACK75574.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 9e-50 | 43 |
| aldA | ACK75590.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 9e-50 | 43 |
| aldA | ACK75596.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 9e-50 | 43 |
| aldA | ACK75585.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 3e-49 | 43 |
| aldA | ACK75593.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 3e-49 | 43 |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 5e-71 | 43 |
| aldA | ACK75582.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 1e-49 | 43 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 6e-74 | 42 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 6e-74 | 42 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 6e-74 | 42 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 3e-65 | 42 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-73 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| RAM_04495 | YP_005528848.1 | NAD-dependent aldehyde dehydrogenase | VFG0082 | Protein | 2e-71 | 43 |
