Gene Information

Name : ureC (RAM_43370)
Accession : YP_005536598.1
Strain : Amycolatopsis mediterranei S699
Genome accession: NC_017186
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 9285127 - 9286842 bp
Length : 1716 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGCCGCAAATCGACCGCGAGCGCTACGCCGAGCTGTTCGGCCCGACCACCGGCGACCGGATCCGGCTCGCCGACACCGA
CCTGCTGATCGAGGTCACCGAGGACCGCTCGATGGGGCCCGGCGGCTCCGGCGACGAAGTGCTCTTCGGCGGCGGCAAGG
TCATCCGCGAGTCCATGGGCCAGGGGACGGCGACCCGGGCCGAGGGCGCGCCCGACCTGATCATCACCGGCGCCGTCATC
CTCGACCACTGGGGCGTCGTCAAGGCCGACGTCGGGGTGCGCGACGGCCGGATCGTCGGCATCGGCAAGGCGGGCAACCC
GGACACGATGGACGGCGTCGACCCGGCGCTGGTGATCGGACCGTCGACGGAGGTCCTGTCCGGCAACGGCAAGATCCTCA
CCGCGGGCGGGATCGACTGCCACGTCCACTTCATCTGCCCGCAGCTCGTCGACACGGCGCTGGCCGCCGGGCTGACCACC
CTGGTCGGGGGCGGCACCGGTCCCAACGAAGGCACCAAGGCCACGACCGTTACCCCCGGCGCGTGGAACCTCGGCCGGAT
GCTGTCCGCCATGGACGGTTACCCGGTCAACGTCCTGTTGCTGGGAAAGGGAAACACCGTGCGGCACGAGGCGCTGCGCG
AACAGCTGGCGGCGGGCGCGGGCGGGTTCAAGCTGCACGAGGACTGGGGCACCACCCCGGCCGCCATCGACGCTTGCCTG
ACCGTCGCCGACGAAGCCGGCGTCCAGGTGGCCATCCACACGGACACGCTGAACGAGGCCGGCTTCCTGGAGTCCACTGT
GGACGCCATCGGTGGCCGCTCGATCAACGCGTACCACACCGAAGGGGCCGGCGGCGGGCACGCGCCGGACATCATCCAGG
TCGTCTCGCTGCCGAACGTGCTGCCGTCGTCGACCAACCCGACCCGCCCGCACACGGCCAACACCCTCGACGAGCACCTC
GACATGCTGGTGGTCTGCCACCACCTCAACCCGTCGGTGCCCGAGGACCTGGCCTTCGCCGAGAGCCGGATCCGGCCGAC
GACGATCGCCGCCGAAGACGTCCTGCACGACATGGGCGCCATTTCGATGATGAGCTCGGACTCCCAGGCGATGGGCCGGA
TCGGCGAGGTGATCATCCGGACCTGGCAGACCGCGCACGTGATGAAACGCCGTCGCGGCGCCCTGCCCGGCGACGGCGCG
GCCGACAACCTGCGGGCGCGTCGCTATGTCGCCAAATACACGATCAACCCGGCCATCGCGCACGGCATGGAGACCGAGAT
CGGCTCGGTCGAGGTCGGCAAGCTCGCGGACCTGGTGCTGTGGGAGCCGAAGTTCTTCGGCGTCCGCCCGCACGTGGTGC
TCAAGGGCGGCTTCCCGGCGTGGGCGGCGATGGGCGACGCGAACGCGTCCATCCCGACCCCGCAGCCGGTCATGGCGCGG
CCGATGTTCGGCGCGTCGATCGGAGCTGCGTTGAGCCTGCACTTCGTCGCACCGTCCGCTTTGGACAGTGGCTTGCGCGA
GACCTTCGGCATCACCCGGCCGCTGGTGGCGGTGTCGAACATGCGCGCACGGACGAAGGCGGACATGGTGCTCAACGACA
CGACACCGGACGTCCGCGTCGAGCCGGACAGCTTCGCCGTGCACGTCGACGGTGAGCTGGTCGAGCCGCAGCCGGTGACG
GAACTGCCGATGGCCCAACGGTACTTCTTGTTCTGA

Protein sequence :
MPQIDRERYAELFGPTTGDRIRLADTDLLIEVTEDRSMGPGGSGDEVLFGGGKVIRESMGQGTATRAEGAPDLIITGAVI
LDHWGVVKADVGVRDGRIVGIGKAGNPDTMDGVDPALVIGPSTEVLSGNGKILTAGGIDCHVHFICPQLVDTALAAGLTT
LVGGGTGPNEGTKATTVTPGAWNLGRMLSAMDGYPVNVLLLGKGNTVRHEALREQLAAGAGGFKLHEDWGTTPAAIDACL
TVADEAGVQVAIHTDTLNEAGFLESTVDAIGGRSINAYHTEGAGGGHAPDIIQVVSLPNVLPSSTNPTRPHTANTLDEHL
DMLVVCHHLNPSVPEDLAFAESRIRPTTIAAEDVLHDMGAISMMSSDSQAMGRIGEVIIRTWQTAHVMKRRRGALPGDGA
ADNLRARRYVAKYTINPAIAHGMETEIGSVEVGKLADLVLWEPKFFGVRPHVVLKGGFPAWAAMGDANASIPTPQPVMAR
PMFGASIGAALSLHFVAPSALDSGLRETFGITRPLVAVSNMRARTKADMVLNDTTPDVRVEPDSFAVHVDGELVEPQPVT
ELPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-147 59
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-147 59
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-149 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-150 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-150 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 6e-150 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_005536598.1 urease subunit alpha VFG0270 Protein 2e-136 56