Gene Information

Name : RAM_42570 (RAM_42570)
Accession : YP_005536438.1
Strain : Amycolatopsis mediterranei S699
Genome accession: NC_017186
Putative virulence/resistance : Resistance
Product : D-lactate dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 9116579 - 9117553 bp
Length : 975 bp
Strand : -
Note : COG1052 Lactate dehydrogenase and related dehydrogenases

DNA sequence :
ATGAGCGAACCGGCACTCGGGATGACGATCTACGGGTGTGCACCCGACGAAGCCGTGCTGTTCCGGGAGATGGCGCCGGG
CTTCGGGGTGACACCGACCATCACCGGTGCGGCGGTGTCCGAGGCCAACGCCGCACTGGCGGCCGGTAACCGGTGCGTCA
GCGTCGGGCACAAGACGCCGCTCACCCGGAGAACTCTTCTCGCGCTCAGCCGGGTCGGCGTCACCTACGTCTCCACGAGG
AGCGTCGGCTACGACCACATCGACGTCGGATACGCCCGGAGCGTCGGCATTTCCGTCGGGAACGTCGCCTATTCGCCGGA
CAGCGTGGCCGACTACACGCTGATGCTGATGTTGATGCTCGTGCGGGACGCCAAGTCCGTCATCCGCCGCGCGGAGGAGC
ACGACTACCGGCTGAACGACGTGCGCGGGAAAGAGCTGCGCGATCTGACCGTCGGGGTGGTCGGGACCGGACGCATCGGT
TCCGCCGTCGTCGGCCGGTTGCGCGGGTTCGGGGCTCGGGTGGTGGCTCACGACTGCTGTCCCCAGGCCGGCCTCGACTA
CGTCGAACTCGACGAACTGCTGCGGCTGAGCGACATCGTCACGCTCCACACGCCACTCGACGCCGGAACGCACCACCTCC
TGGACCGACGGCGGCTCGAGCGGATGAAGCCCGGAGCGTTCGTCGTCAACACCGGGCGAGGCCCCCTTCTCGACACCGAG
GCGCTCGTCGCGGCACTGGAAAACGGCAGGCTGGGCGGCGCCGCGCTGGACGTCCTCGAAGGGGAAGAAGGCGTCTTCTA
CGCCGACTGCCGCGATCGGCCCGTCGACAGCGACCTGCTGGTGCGGCTGCAGAAGCTGCCGAACGTGCTGATCAGCCCGC
ACACCGCGTACTACACCGACCACGCGCTCGGCGACACCGTCGAAAACTCCATCATCAACTGCTTGAACTTCGAAAGCGGG
AAGCGGCATGAATAG

Protein sequence :
MSEPALGMTIYGCAPDEAVLFREMAPGFGVTPTITGAAVSEANAALAAGNRCVSVGHKTPLTRRTLLALSRVGVTYVSTR
SVGYDHIDVGYARSVGISVGNVAYSPDSVADYTLMLMLMLVRDAKSVIRRAEEHDYRLNDVRGKELRDLTVGVVGTGRIG
SAVVGRLRGFGARVVAHDCCPQAGLDYVELDELLRLSDIVTLHTPLDAGTHHLLDRRRLERMKPGAFVVNTGRGPLLDTE
ALVAALENGRLGGAALDVLEGEEGVFYADCRDRPVDSDLLVRLQKLPNVLISPHTAYYTDHALGDTVENSIINCLNFESG
KRHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 4e-88 59
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-87 58

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RAM_42570 YP_005536438.1 D-lactate dehydrogenase AF155139.2.orf4.gene Protein 1e-92 62
RAM_42570 YP_005536438.1 D-lactate dehydrogenase NC_014475.1.orf2.gen Protein 4e-92 59
RAM_42570 YP_005536438.1 D-lactate dehydrogenase NC_005054.2598279.p0 Protein 4e-92 59
RAM_42570 YP_005536438.1 D-lactate dehydrogenase U35369.1.gene5.p01 Protein 1e-87 58
RAM_42570 YP_005536438.1 D-lactate dehydrogenase AF310956.2.orf4.gene Protein 7e-88 58
RAM_42570 YP_005536438.1 D-lactate dehydrogenase AF130997.1.orf3.gene Protein 6e-79 56
RAM_42570 YP_005536438.1 D-lactate dehydrogenase FJ349556.1.orf3.gene Protein 4e-88 56