Gene Information

Name : lysS (RAM_06140)
Accession : YP_005529177.1
Strain : Amycolatopsis mediterranei S699
Genome accession: NC_017186
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 1277717 - 1281040 bp
Length : 3324 bp
Strand : +
Note : COG2898 Uncharacterized conserved protein

DNA sequence :
ATGGGAAACCTCGCGAGCTCGCGCCCTCGCCTCCCCGCCTGGAAGGCGAAGGCGGGCGGCATCGCCGCGACCGTGGTCCA
GCTGGCCGCGGTGTTCTCCGTGATCCTGCTCTTCACCGGCGGCCCGCACGGCCGCGTGCTCAACGGCATCGACATGGCCT
TCTCCGGCTTGAGCGTGCCGACCAGCGAGAGCCTGATCATGGTGCTGCTGCTGGTGGTGCTCGGAGCCGCCCTGCGCCGC
CGCAAGAAGGCCGCGCTGTACACCCTGGTGCTGTTCCAGGTCGGCGGGCTGCTGCTCACGCTGGCCCTCCAGGCGACCCT
GCTCTGGTCACCCGACGTGCTGACCCTCGGCCCGAAGCAGGTCCGGCACATCCCCGCGCAGCTGTGGGTGCTGACCATCG
CCGACGCCGTCTCGGTCGGGCTGATCGTGCTCCTGCTCGCGCTGCGCCCGGCGTTCCCGGCCCGCCTCGCGCCGAGCGCC
TGGCGCGACGGCCTGAGCATGCTGTTCGGCGGCATCGCCGTGGTCATCCTGGTCGGGTGGGGCCTGACCGAGGCGTTCCC
CGGCCACCTCGGCGACACGTGGGAGCGCTTCGCCTGGGTCGTCAACCACGCCACGGGCGAGAACCTGCAGCTGCGCCGGA
TCGGCGTGGGCGAAGGGCCCGGCTGGCTGGACCTGTTCCTCGACCTCAGCGCGACGGCGGTCGCCACCGCGGCGCTGTAC
CTGCTCTTCCGCGGCGTGCGCAGCCGCGCCCTGCGGACCGACGAGGACGAGCTCCGCCTGCGCCGGCTGCTCGCCGAACA
CGGCGAGGACGACTCCCTCGGCTACTTCGCCACCCGGCGCGACAAGAGCGTCGTCTTCGCGCCGAACGGCCGCGCGGCGG
TGACCTACCGCGTCCTCGGCGGCACGAGCGTCGCCAGCGCCGACCCGGTCGGCGACCCGGAGGCGTGGCCCGACGCGGTC
CGGGCGTGGCTCGACGAGACGCGCACGTACGGCTGGACCCCGGGCGTGCTCGGGGCGAGCGAACGCGGCGCGAAGGCGTA
CACCGGGGCGGGTCTGCGTGCCCTGGAAATCGGCGACGAAGCGGTGCTCGACGTCCGCGAGTTCAGCCTGGCCGGCCCGG
AGCGGCGCTCGGTGCGCCAGGCCGTCAAGCGCATCGAGCGGGCCGGCTACACCTCGCGGGTCCGCCGCCACGGCGAGATC
CCCGAGGCCGAGATGACCGAGCTGCTCGCCCGGGCGCAGGCCTGGCGCGGCGCCGAGACCGAACGCGGGTTCTCGATGGC
GCTGGGCCGGCTCGGCGACGCCAGCGACGGCCGCAGCGTGATGGTCGAGGCCTACGACGCCCACGGCGAGCTGCGCGGGC
TGCTGTCGTTCGTCCCGTGGGGGCGCCGCGGGCTTTCGCTGGACCTCATGCGCCGCGACCGCGACGCCGAGAACGGCCTC
AACGAGTACATGATCGCCGAGACGGTCGCGGCCGCGCAGGTCCTCGGCGCGCAGCGGATCTCGCTCAACTTCGCGATGTT
CCGCGCGGTGTTCTCCGAGGGCGAGCGGATCGGCGCCGGCCCGGTGCTGCGGGCCTGGCGTGGCATCCTCAGCGTGTTTT
CGCGGTTCTTCCAGCTGGAGTCGCTGTACCGGTCCAACGCCAAGTACGGGCCGGACTGGGAGCCGCGGTTCCTCTGCTAC
TCCTCGGCCCGGCGGCTGCCGCGGGTCGGCATCGTCGCGGGCGCGCTCGAAGGGTTCGTCCCGACCGGACGGGCGCGGTC
GCTGCGGCTGGAGACGGTCAGCGAGGACTTCGTCGCGCGCGTCAAGGAGATCGAGGAGTCGGCGGCGGCACCGGCGCCGA
AGGCCTGGCGGCGGCCCGAACAGGTCCGCGTCCGCATCGCCAAGCTCGACAAGCTGCGCGAGGCCGGCATCGACCCGTAC
CCGGTCGGTTTCCGCCGCGACGACCACATCGGGGACGTCGTGGCGAAGTACGGCGACCTGGCGCCGGACACCACCACCGG
GCACCGGGTCCGGATCGCCGGGCGGGTGCTGAACCTGCGCATCCTCGGCGGCCTGTGCTTCGCCCGCGTCAAGGACTTCA
GCGGCGAGATCCAGCTGATGCTGGAGGCCGGCGAGCTGGACCTGACCCGCTGGCGGACCGGCGTCGACCTCGGCGACCAC
GTCGGCGTCAGCGGCCAGGTCGTGACGTCGAAGCGCGGCGAGCTTTCGGTGCTCGTCGACGAGTGGACGGTCACCGCGAA
GTGCCTGCACCCGCTGCCCGACAAGCGAAAGGGCCTCACCGACCCGGAGACGCGGGTCCGGCAGCGCTACCTCGACCTGG
CGGTCAACCCGGACTCGACGAACATGCTGCGGCTGCGGTCCACCGTGGTCCGCGCGGTGCGCGACCGGCTGCACCACGCC
GACTACCTCGAGGTCGAGACGCCGATGCTGCAGACGGTGCACGGCGGCGCCAACGCCCGGCCGTTCGTCACCCACATCAA
CGCCTACGACATGCGGATGTACCTGCGGATCGCGCCCGAGCTGTACCTGAAGCGGCTGTGCGTGGCCGGCGTCGAGCGGG
TCTTCGAGCTCAACCGCAACTTCCGCAACGAAGGCGTCGACGCGACGCACAACCCCGAGTTCACGATGCTCGAGGCGTAC
CAGGCGTACGCGGACTACGACACGATGCGGACGCTGACCCGCGAACTGGTCCAGCACGCGGCCGAAGCGGCGTACGGGGC
TCAGGTCGTCCGGCGGCCCGACGCCGACGGGAAGGTCGTCGAGTACGACATCTCCGGCGACTGGCCGGTCGTGCCGGTCC
ACGAAGCCGTCTCGGCGAGGTTCGGCGAGGAGATCGACCCGGGGACGCCGGTGGCCGAGCTGCGCCGCCTGTGCGTGGCC
GCCGGGGTGCCGGTGGGGGAGGACCCGAGCCACGGCGACCTCGTGCTCAAGGCGTTCGAGCACCTCGTCGAGGGCGCGAC
CGTGCTGCCGACGTTCTACACCGACTACCCGACCGACGTCTCGCCGCTGACCCGCCAGCACCGGGTGGACCCGCGGCTGG
CCGAACGCTGGGACCTCATCGCGTTCGGGTCGGAGGTCGGCACGGCCTACACCGAGCTGACCGACCCGATCGAGCAGCGG
CGGCGGCTGGAAGGGCAGTCGCTGCGCGCGGCCAGCGGTGACGTCGAGGCGATGGAGCTGGACGAAGACTTCTTGCTCGC
CTTGGAGCACGGGATGCCGCCGACCGGCGGGCTCGGCCTGGGCGTCGACCGGCTGCTCATGATGCTCACCGGTGCCTCCA
TCCGCCAGACGGTCCTGTTCCCCTTCGTCCGACCGCAGGCATAA

Protein sequence :
MGNLASSRPRLPAWKAKAGGIAATVVQLAAVFSVILLFTGGPHGRVLNGIDMAFSGLSVPTSESLIMVLLLVVLGAALRR
RKKAALYTLVLFQVGGLLLTLALQATLLWSPDVLTLGPKQVRHIPAQLWVLTIADAVSVGLIVLLLALRPAFPARLAPSA
WRDGLSMLFGGIAVVILVGWGLTEAFPGHLGDTWERFAWVVNHATGENLQLRRIGVGEGPGWLDLFLDLSATAVATAALY
LLFRGVRSRALRTDEDELRLRRLLAEHGEDDSLGYFATRRDKSVVFAPNGRAAVTYRVLGGTSVASADPVGDPEAWPDAV
RAWLDETRTYGWTPGVLGASERGAKAYTGAGLRALEIGDEAVLDVREFSLAGPERRSVRQAVKRIERAGYTSRVRRHGEI
PEAEMTELLARAQAWRGAETERGFSMALGRLGDASDGRSVMVEAYDAHGELRGLLSFVPWGRRGLSLDLMRRDRDAENGL
NEYMIAETVAAAQVLGAQRISLNFAMFRAVFSEGERIGAGPVLRAWRGILSVFSRFFQLESLYRSNAKYGPDWEPRFLCY
SSARRLPRVGIVAGALEGFVPTGRARSLRLETVSEDFVARVKEIEESAAAPAPKAWRRPEQVRVRIAKLDKLREAGIDPY
PVGFRRDDHIGDVVAKYGDLAPDTTTGHRVRIAGRVLNLRILGGLCFARVKDFSGEIQLMLEAGELDLTRWRTGVDLGDH
VGVSGQVVTSKRGELSVLVDEWTVTAKCLHPLPDKRKGLTDPETRVRQRYLDLAVNPDSTNMLRLRSTVVRAVRDRLHHA
DYLEVETPMLQTVHGGANARPFVTHINAYDMRMYLRIAPELYLKRLCVAGVERVFELNRNFRNEGVDATHNPEFTMLEAY
QAYADYDTMRTLTRELVQHAAEAAYGAQVVRRPDADGKVVEYDISGDWPVVPVHEAVSARFGEEIDPGTPVAELRRLCVA
AGVPVGEDPSHGDLVLKAFEHLVEGATVLPTFYTDYPTDVSPLTRQHRVDPRLAERWDLIAFGSEVGTAYTELTDPIEQR
RRLEGQSLRAASGDVEAMELDEDFLLALEHGMPPTGGLGLGVDRLLMMLTGASIRQTVLFPFVRPQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 3e-163 47
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-163 47
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-163 47
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-163 47