Gene Information

Name : A1122_03000 (A1122_03000)
Accession : YP_005520297.1
Strain : Yersinia pestis A1122
Genome accession: NC_017168
Putative virulence/resistance : Resistance
Product : putative multi-drug efflux protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 663497 - 666583 bp
Length : 3087 bp
Strand : -
Note : COG0841 Cation/multidrug efflux pump

DNA sequence :
ATGAAGCTGACTGATAATTTTATCAATAATAATACCCGTATCTGGCTAACGATTCTGTTGCTAGGTATTGGTGGCATTAT
TGCCTATCTCAATATAGGCAGGCTGGAAGACCCGGCTTTTACCATCAAAACCGCGGTCGTTGTCACCCGCTATGATGGCG
CATCGGCACAACAGGTTGAAGAAGAAGTCACGCTACCGTTGGAGAATGCCATTCAGGAACTCTCCTATGTGGATGACGTA
ACCTCCATTTCCAGTGCCGGTTTATCGCAGATAACCATTAATATTCGTGCGCAATACGGCGCGAATGAGTTACCGCAAAT
CTGGGATGAGCTGTGGCGTAAAATTAGCGATAACAGTGTTCGCCTACCACCAGGGGCCAGTGCCCCCATGGTCAACGATG
ATTTTGGCGATGTTTACGGTTTCTTCTTCTCACTGACCGGTGACGGCTACAGTAATCAGGATCTGCGTAATTTTGCCGAG
CAATTGCGGCGTGAATTAGTGTTGGTGCCCGGTGTGGGTAAAGTCGGCATCGTGGGTATTTTACCGGAAGAAGTTCAGGT
AGAAATTTCCCGTGCGCAGATGACGGCCGCGGGTATTACACCGCAGCAGCTATCCGACTTGCTGAGTCGCCAAAACGTCG
TGTCCGATGCAGGCCAGTTGCAGGTGGGCAGTGAGTCGATTCGCTTGCACCCGACTGGCGAATTCCAAAGCGTACAAGAG
CTGGGGAATTTACTGGTCAGCCAACCCGGTAGCCCAAAAAGTGTCTATCTGCGCGATATTGCCACGGTAACCCAAGGCTT
TGGTCATTCACCGACCAATATTTATCGCGCGAACGGTCAACCGGCATTGGCGTTAGGGATCTCGTTTGCTCCCAATGTTA
ACGTGGTAAATGTTGGGAATGCGATTAAATCCCGTCTGGCGCAGCTTGAAGGTGAGCGCCCGTCCGGGATGCATATCAAT
GTGTTCTACGATCAGTCTAAGGAAGTTGAAGGTGCGGTTAACGGCTTCATTCTTAACTTCCTGTTGGCACTGTTGATTGT
TGTCGTTACCCTGCTGATCTTTATGGGGGTACGCAGCGGCGTGGTTATTGCCATCTCGCTGGCACTTAACGTGCTCGGAA
CGTTGCTCATCATGTGGCTGTTTAACATCGAGCTACAGCGGGTATCGTTAGGGGCGCTGATCATTGCGCTGAGTATGCTG
GTGGATAACGCCATCGTGGTGGTGGAAGGGGTGGTCGTTGGGCGTCAGCGCGGCGATAGCATTTCTACTGCTATCGGTAA
TGTGGTGAAACGCTCGAAGATGCCGTTGCTGGGTGCGACCATTATTGCCATTTTGGCCTTTGCGCCTATCGGCCTGTCCA
ATGATGCTACCGGCGAATATTGTAAGTCGCTATTCCAGGTGTTGCTCATCTCGTTAATGTTGAGCTGGATCACTGCGTTA
ACGTTAACACCGGTGTTTGCCAAGTGGGCATTCCAGAACCAAAAACAGCCTGAAGCTGATGCGGATAAGCCGGTTAAACA
ACCGTATGACGGCTGGTTATTCCGCTATTATCGGGTGGTGTTGAATAAATTACTGCAACACCGCAGTATTACATTGGTGC
TCTTGGCCGCGTTATTAGTGGCGTCGGTTATCGGTTTTGGTCATGTTCGACAGAGCTTCTTCCCGCCTTCTAACACACCA
ATCTTCTTTGTGGATATTTGGCTGCCTTATGGTACGGATATCAGCTATACCGAAGATATTGCAGCCAAAATTGAACAGCA
TATCAAGCAGCAAAAAAATGTAGCGGATACCATGACAACCATAGGTCAGGGCGCAATGCGCTTTATGCTGACCTACAATG
GTCAACGTCATTATCCTAACTATGCGCAGGTGATGGTCCGTACTGAGCAACTGGAGCAAATACCGGGCTTGATTGATGAA
ATCGAGTCATATATGCATGACGAATATCCGCAGGTTGATGCGCAGATCAAACGCATCATGTTCGGGCCGTCAAACAACAG
TTCTATTGAAGCTCGCTTTATTGGCCCCGATCCAGATGTGCTACGCACCTTGGCAGCCCAGGCGGAACAGGCGATTATCG
CTGACCCAATGGCCGATGGTGCAAGGCATGACTGGCAGGATCGTAGCAAGATGATCCGGCCACAATTCTCCGATTATCTG
GGCCGCGAGTTGGGGGTCGATAAACGCGAGGTGGATGGTACGTTGCGCATGAGTTTTGGTGGCTTGCCGGTTGGGTTATA
CCGCGATGGTACCCGCCTGATACCTATTGTCCTACGCACACCGGACTCTGAGCGGCTCAATGCTGAGCGGTTGAACGATG
TGATGGTCTGGAGCCAGGCGCGCCAAGCCTTTATCCCGATCGACAACGTGGTCACCAGTTTTGAAACCGAGTGGGAAGAT
CCACTGATTATGCGTCTGGATCGTAAGCGGACACTGACGGTACAAACGGATCCAACCCATCAGGGCGGTGAGACCTCTTC
CGAGTTGTTGCAACGGATCAAGCCGGGCGTTGAAGCCATTACCTTGCCACGGGGCTATGAACTGGAGTGGGGCGGCGATT
ACGAAAGTACCAAAGAAGCACAGCGGGGTATTTTCATTAGCTTGCCGATCGCGTTTCTGCTTATGTTTGTTGTGACCGTG
CTGATGTTTAGCTCGGTGCGTAATGCACTGGCTATTTGGCTGACGGTACCACTGGCATTAATTGGTGTGACCTTCGGCTT
CCTACTGACGGGGATTCCGTTCGGCTTTATGGCCTTGCTGGGGTTATTAAGCCTGAGTGGGATGTTGATCCGTAATGGTA
TTGTACTGGTCGAAGAGATTGGTCTACAGCGGCAAGAGAAACCGTTGCGTGAGGCGATTATCGATGCTTCCACCGCGCGT
TTACGGCCGATCATGCTGACCGCATTTACCACTGTGTTGGGGCTGGCTCCGCTGCTGAGCGATGCCTTCTTCCAGAGTAT
GGCGGTGGTGATTATGTTTGGCTTGGGCTTCGCGACAGTACTGACATTGCTGGTACTGCCAGTGATTTACAGCAGTATGA
ATCCAGAGCCTAAAGAAAAGATCCACGATGAGCCAGTGAGTGAATAA

Protein sequence :
MKLTDNFINNNTRIWLTILLLGIGGIIAYLNIGRLEDPAFTIKTAVVVTRYDGASAQQVEEEVTLPLENAIQELSYVDDV
TSISSAGLSQITINIRAQYGANELPQIWDELWRKISDNSVRLPPGASAPMVNDDFGDVYGFFFSLTGDGYSNQDLRNFAE
QLRRELVLVPGVGKVGIVGILPEEVQVEISRAQMTAAGITPQQLSDLLSRQNVVSDAGQLQVGSESIRLHPTGEFQSVQE
LGNLLVSQPGSPKSVYLRDIATVTQGFGHSPTNIYRANGQPALALGISFAPNVNVVNVGNAIKSRLAQLEGERPSGMHIN
VFYDQSKEVEGAVNGFILNFLLALLIVVVTLLIFMGVRSGVVIAISLALNVLGTLLIMWLFNIELQRVSLGALIIALSML
VDNAIVVVEGVVVGRQRGDSISTAIGNVVKRSKMPLLGATIIAILAFAPIGLSNDATGEYCKSLFQVLLISLMLSWITAL
TLTPVFAKWAFQNQKQPEADADKPVKQPYDGWLFRYYRVVLNKLLQHRSITLVLLAALLVASVIGFGHVRQSFFPPSNTP
IFFVDIWLPYGTDISYTEDIAAKIEQHIKQQKNVADTMTTIGQGAMRFMLTYNGQRHYPNYAQVMVRTEQLEQIPGLIDE
IESYMHDEYPQVDAQIKRIMFGPSNNSSIEARFIGPDPDVLRTLAAQAEQAIIADPMADGARHDWQDRSKMIRPQFSDYL
GRELGVDKREVDGTLRMSFGGLPVGLYRDGTRLIPIVLRTPDSERLNAERLNDVMVWSQARQAFIPIDNVVTSFETEWED
PLIMRLDRKRTLTVQTDPTHQGGETSSELLQRIKPGVEAITLPRGYELEWGGDYESTKEAQRGIFISLPIAFLLMFVVTV
LMFSSVRNALAIWLTVPLALIGVTFGFLLTGIPFGFMALLGLLSLSGMLIRNGIVLVEEIGLQRQEKPLREAIIDASTAR
LRPIMLTAFTTVLGLAPLLSDAFFQSMAVVIMFGLGFATVLTLLVLPVIYSSMNPEPKEKIHDEPVSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 3e-166 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A1122_03000 YP_005520297.1 putative multi-drug efflux protein BAC0519 Protein 0.0 51
A1122_03000 YP_005520297.1 putative multi-drug efflux protein BAC0428 Protein 0.0 51
A1122_03000 YP_005520297.1 putative multi-drug efflux protein BAC0526 Protein 0.0 48
A1122_03000 YP_005520297.1 putative multi-drug efflux protein BAC0425 Protein 1e-166 41