Gene Information

Name : ureC (A1122_12755)
Accession : YP_005522203.1
Strain : Yersinia pestis A1122
Genome accession: NC_017168
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 2768395 - 2770113 bp
Length : 1719 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGCCTCAAATTTCTCGGCAAGAATACGCGGGTCTATTTGGCCCAACAACTGGCGATAAAATCCGTTTGGGTGATACCAA
TCTGTTTATCGAAATCGAAAAAGACTTGCGTGGATATGGTGAAGAGTCGGTTTACGGTGGTGGGAAATCGCTGCGTGACG
GGATGGGGGCCAACAATAATCTGACCCGCGATAATGGTGTGCTTGACCTGGTGATTACCAACGTCACGATTGTCGATGCT
CGCTTAGGGGTGATTAAAGCTGACGTCGGTATCCGCGATGGCAAAATCGCCGGTATCGGTAAGAGCGGTAACCCCGGTGT
TATGGATGGGGTTACGCAGGGTATGGTGGTCGGTGTGAGCACCGATGCTATCTCTGGTGAGCATTTGATTCTTACTGCCG
CCGGTATCGATAGCCATATTCATCTCATCTCCCCGCAACAGGCCTATCATGCGCTGTCCAACGGTGTTGCAACATTCTTT
GGTGGGGGGATTGGTCCAACGGATGGCACTAACGGGACAACCGTAACACCAGGGCCGTGGAATATCCGTCAAATGCTGCG
TTCGATAGAGGGGTTACCTGTCAACGTTGGTATTTTGGGGAAAGGTAATTCATACGGGCGCGGCCCGTTGCTGGAACAGG
CTATTGCCGGTGTTGTGGGCTATAAAGTTCATGAAGACTGGGGCGCGACGGCGAATGCTTTGCGTCATGCGCTGCGGATG
GCGGATGAGGTGGATATTCAGGTTTCGGTTCATACCGATAGCCTGAATGAATGTGGTTATGTAGAAGATACTATCGATGC
GTTCGAAGGCCGCACGATCCACACGTTCCACACCGAAGGGGCGGGTGGGGGCCATGCGCCGGATATTATTCGGGTGGCCA
GCCAAACTAACGTACTGCCAAGTTCAACCAACCCCACCCTGCCGTATGGTGTTAACAGCCAGGCTGAGCTGTTTGACATG
ATTATGGTGTGTCACAACCTTAACCCGAACGTACCTGCTGACGTCTCCTTTGCCGAAAGCCGTGTGCGCCCAGAAACGAT
TGCTGCTGAAAACGTTCTGCACGATATGGGCGTTATCTCCATGTTCTCCAGTGACTCACAAGCCATGGGGCGAGTGGGGG
AGAACTGGTTGCGTATTTTGCAAACCGCGGATGCGATGAAAGCGGCTCGGGGCAAATTGCCGGAAGATGCGGCGGGTAAC
GATAATTTCCGCGTGCTGCGCTATGTGGCAAAAATCACCATTAACCCCGCGATTACACAGGGGGTTAGCCATGTTATCGG
ATCGGTTGAAGTGGGCAAAATGGCCGATCTGGTGCTATGGGATCCTCGCTTCTTTGGTGCGAAACCGAAGATGGTTATCA
AGGGGGGCATGATTAACTGGGCCGCGATGGGCGATCCAAATGCGTCACTGCCAACACCACAGCCAGTGTTCTACCGCCCA
ATGTTTGGCGCGATGGGCAAAACGCTACAAGACACTTGTGTCACTTTCGTTTCTCAGGCTGCACTTGATGATGGTGTGAA
AGAGAAAGCGGGGCTGGATCGCCAAGTGATAGCGGTTAAAAACTGCCGCACGATCTCCAAACGTGATCTGGTGCGTAATG
ACCAAACACCAAACATTGAAGTGGATCCTGAAACCTTTGCAGTAAAAGTGGATGGGGTACATGCCACCTGTGAGCCAATT
GCAACTGCGTCGATGAATCAGCGCTATTTCTTTGGCTAA

Protein sequence :
MPQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIVDA
RLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVSTDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFF
GGGIGPTDGTNGTTVTPGPWNIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRM
ADEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLPSSTNPTLPYGVNSQAELFDM
IMVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVISMFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGN
DNFRVLRYVAKITINPAITQGVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRP
MFGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIEVDPETFAVKVDGVHATCEPI
ATASMNQRYFFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-152 58
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-152 58
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-140 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-140 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-140 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-140 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_005522203.1 urease subunit alpha VFG0270 Protein 5e-148 59