Gene Information

Name : A1122_11245 (A1122_11245)
Accession : YP_005521909.1
Strain : Yersinia pestis A1122
Genome accession: NC_017168
Putative virulence/resistance : Virulence
Product : Clp ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2470122 - 2472797 bp
Length : 2676 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
GTGGCTATTACAAGGAAACATCTCTTCGGCAAGCTGGACGCCACTCTTTTCAAAGGTATTGAAAGCGCAACAACGATTTG
TAAATTACGCGGCAATCCTTACGTAGAGTTAGTTCACTGGTTGAATCAGCTTTGGCATCAGGAAGATAACGACCTTAAGC
AGATTATTCGGTATTTTGCGGTGGATGTGGATGCCTTTGAGCGTGAACTGGCTCAGGCACTTGCGAAGTTACCTGTTGGG
GCAACTAGCATTTCAGATTTTTCGTATCATATTGAGTTGGCCACGGAACGGGCTTGGATCTATGCCAGCCTGGAGTGTTT
AGATACCCGTATCCGCAGCGGACATCTGCTGCTTGCGCTATTAACCACAATGGAACTGCGGAGAGCTTTCTTTGCGATTG
CGCCAAGCATGGAAAAAATTCCATTAGAGCATTTAAGCAAAGATTTGAACTTCATTACGCAGGCATCACCAGAAGCGAAT
GAAGCCGCCAGTGATGGCAGCCCGTTGTACGATGGTGCTTTACCTGGCGAAGCCAGTAATGCCATTGGTGCAGCCAAAAG
TGGTGGCGCACTGGCTCAATACACCACAGACCTCACGGCATTAGCACGTGAAGGCAAGATAGATCCGGTATTGGGACGTA
ATCACGAAATCAACACAATGGTTGATATTCTCTTGCGCCGTCGGCAGAACAACCCATTACTTACCGGTGACGCAGGGGTG
GGTAAAACCGCCATTGTTGAAGGGCTAGCATTGGCTATTGCTGCTGGCTCAATGCCACCAGCATTAAGCCAGGTAAGCCT
GTTGTCATTAGATATTGTGGCGCTCTCAGCGGGTGCCAGCATGAAAGGTGAATTTGAAGCGCGCCTGAAGAGTGTCTTGG
ATGAAGCGATAGCGGCAGAAAAGCCCGTTATTTTGTTTATCGATGAAGTACACACACTTATTGGCGCGGGTGGCAATGCC
GGGACCGGCGATGCGGCGAACTTATTGAAACCTGCATTGGCGCGTGGCCAGTTACGTACCATTGGTGCGACAACGTGGAG
CGAGTTCAAGCGTCACATTGAGAAGGATCCGGCACTCACCCGTCGTTTCCAAGTACTTCAAGTTGATGAGCCCGATGAGA
ACACGGCGATCTCCATGTTACGGGGCCTGATACCTGCGCTAGAAAAGCACCACGGCGTGTGGATTATGGACGAAGCTTTA
CAGGCGGCAGTACGGTTGTCTCATCGTTATATCCCTGCGCGTCAGTTGCCGGATAAAGCGATAAGTCTGCTTGATACGGC
TTGTGCACGGATCGCTGTCGCGCAGTTTTCACAACCAATAGAGCTACAGCACTTAACCTTCCAGAGTGAGACGGCGCAAA
CTGAGCTGGTTTCCTTAGAGAAAGCGCGGCACTTTGGTAAAGCGCAGGATGCGCGTACTGAGCAGTTGAAAACATCCATT
GCTGAACATGGCGAGGCTGCGGATAAGCTTGATCAGCGTTGGCAGGCAGAACGCGAATTGGTATCAGCGATTACGACCAT
AAGAACCGCACTGTATGACTTGGTTTCTCAGCCAGAGCCTGATGAGGAAAAACGTCGGGCTTATCAAGCGCAATTAGTTC
AGTTGGAAGCGCAGCTTTCTCAGGTTCGCACTTCACTGCCGTTAGTGCAGACAGAAGTCAACGCTGAAGTGATTGCCAGT
ATCGTTGCGGATTGGACCGGCATTCCGGTTGGGCAAATGCTCAAAGACGATATTCGGGCGGTAATGGAGTTGCCACAGCG
CCTTGAAGCACGTGTTATTGGTCAGCCCCATGCATTGATGCAACTGGGTGAAAATATTATGACCGCACGCGCTGGCCTGT
CAGACCCAAGGAAACCATTGGGGGTCTTTATGTTAGTGGGGCCTTCAGGTGTGGGTAAAACAGAGACGGCCTTAGCGATC
GCCGAGAGCATGTATGGTGGTGAACAGAATATGATCACTATCAATATGAGCGAATATCAGGAATCGCATACCGTTTCCTC
TTTAAAAGGTTCTCCACCGGGATATGTTGGATACGGTGAAGGCGGTGTGTTAACGGAAGCTGTGCGCCGTAAGCCATATA
GTGTTGTGTTGTTAGATGAAATCGAAAAAGCGCACTCTGATGTACATGAGTTATTCTTCCAAGTGTTTGATAAAGGCCAA
ATGGAAGATGGTGAAGGGCGTTTTATCGATTTTAAAAATACTATCTTGTTGTTAACCAGTAATGTGGGCAGCGAGTTACT
GAGTAACTTATTAGCTGATCCAGATACTGCACCGGATCAGGATGGAATATTAAGTGCGTTGCAACCTGAATTGCTGAAAG
TTTTCCCCGCAGCATTTTTAGGGCGAGTTACGGTTATTCCTTATCTTCCGTTACAGCAAGATGCATTGCAGCATATTGTA
CGGTTGCATTTAGATCGGATTGGCGCTCGTTTATACTCGCAGCATCAATTGACACTGAAATACAGTGATGAAGTGGTTGA
AGATGTTGTTAGCCGCTGTGCGGTCTCAGAGACCGGTGCGCGTATGCTGATCCGTTACATTGAACAAAATATTACGCCAA
AAATAGGTAAATATATTTTAGGTGATAGTGATGTGAAGCCTGAGCAAATTATTTTCGTTCATAAAAATGAAAATGGATTC
GTGATCGCTTTACAGTGTAAAGATGACGAAAACTAA

Protein sequence :
MAITRKHLFGKLDATLFKGIESATTICKLRGNPYVELVHWLNQLWHQEDNDLKQIIRYFAVDVDAFERELAQALAKLPVG
ATSISDFSYHIELATERAWIYASLECLDTRIRSGHLLLALLTTMELRRAFFAIAPSMEKIPLEHLSKDLNFITQASPEAN
EAASDGSPLYDGALPGEASNAIGAAKSGGALAQYTTDLTALAREGKIDPVLGRNHEINTMVDILLRRRQNNPLLTGDAGV
GKTAIVEGLALAIAAGSMPPALSQVSLLSLDIVALSAGASMKGEFEARLKSVLDEAIAAEKPVILFIDEVHTLIGAGGNA
GTGDAANLLKPALARGQLRTIGATTWSEFKRHIEKDPALTRRFQVLQVDEPDENTAISMLRGLIPALEKHHGVWIMDEAL
QAAVRLSHRYIPARQLPDKAISLLDTACARIAVAQFSQPIELQHLTFQSETAQTELVSLEKARHFGKAQDARTEQLKTSI
AEHGEAADKLDQRWQAERELVSAITTIRTALYDLVSQPEPDEEKRRAYQAQLVQLEAQLSQVRTSLPLVQTEVNAEVIAS
IVADWTGIPVGQMLKDDIRAVMELPQRLEARVIGQPHALMQLGENIMTARAGLSDPRKPLGVFMLVGPSGVGKTETALAI
AESMYGGEQNMITINMSEYQESHTVSSLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEIEKAHSDVHELFFQVFDKGQ
MEDGEGRFIDFKNTILLLTSNVGSELLSNLLADPDTAPDQDGILSALQPELLKVFPAAFLGRVTVIPYLPLQQDALQHIV
RLHLDRIGARLYSQHQLTLKYSDEVVEDVVSRCAVSETGARMLIRYIEQNITPKIGKYILGDSDVKPEQIIFVHKNENGF
VIALQCKDDEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 0.0 59
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 9e-130 46
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-129 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A1122_11245 YP_005521909.1 Clp ATPase VFG2076 Protein 0.0 55
A1122_11245 YP_005521909.1 Clp ATPase VFG2084 Protein 3e-138 44