Gene Information

Name : Hydth_1794 (Hydth_1794)
Accession : YP_005512468.1
Strain : Hydrogenobacter thermophilus TK-6
Genome accession: NC_017161
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1644440 - 1646482 bp
Length : 2043 bp
Strand : +
Note : COGs: COG2217 Cation transport ATPase; InterPro IPR018303:IPR001757:IPR000695:IPR006403:IPR 006416:IPR008250:IPR005834; KEGG: aae:aq_1125 cation transporter E1-E2 family ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain pr

DNA sequence :
ATGCACCCGGAGGTGAAGAGAGAATCACCGGGTAAATGTCCCAAGTGTGGCATGGACCTTGTCCCAACTGAACATCCTCC
AAGAAAACACCACCACACCATGCACATGGAGGAAATGAAAAGGAAGGCTATAGTTTCAACAGTCCTCACGATTCCCGTCG
TTCTTTACTCCAAAAATATACAGAATCTCCTTCGCTTTTCCATGCCAGAGTTTCCTGGGAGCGAGTGGATAACACCTATT
TTATCCGCAATTGTTTTCTTTTACGGAGGGACCTTTTTCCTCAAGGGCATGGCAGAGGAATTAAGGCTCAAAAAGCCCGG
AATGATGACCCTTATAGGCATAGCCATATGGGTTGCCTTTATATACAGCCTCTCAACTCTATTACTTGGTGGAATGGAGT
TCTTCTGGGAGCTTGCCACACTCATAGTGGTGATGCTCTGGGGACACTGGATAGAGATGAGGTCTGTACTGGGAGCTTCG
CGTGCCGTTGAGGAGCTGGCAAAGCTCATGCCTACCAAAGCAAACCTTCTAAAGGACGGGGAGATAGTTGAGGTTCATGT
CTCTGAGCTAAAGCCCGGTGATATAGTCTTGGTAAAACCTGGGGAGAAGATACCAGCGGACGGGATTGTCATAGAAGGAT
TAACCCACATGAACGAGGCTATGCTCACAGGCGAATCTAAGCCAGTTCCCAAAGGCGTAGGTGACAGAGTCATAGGCGGT
GCCATAAACATGGAAGGCTCCATAAAGGTGAAGGTTGAGAAGACTGGTGAGGAGACCTATCTAAGCCAAGTTCTGAAGCT
CGTCAAAGAAGCTCAGGAGTCAAAAACAAAACTCCAGGACATGGCGGACAGAGTGGCGTTTTACCTCACCGTGATTGCCA
TAGTGGTCGGAAGCCTTGCCTTTCTTGTCTGGCTGTACCTCAAGGGGGACCTTCAGTTTGCTGTTGAGAGAGCTGTGACG
GTGATGGTAATAGCCTGTCCCCATGCTCTCGGGCTTGCCATACCTCTGGTTGTAGCCATATCCACCTCCTACTCAGCTAA
GAACGGGATATTAGTTAGAAACAGGCTTGCTCTTGAAACTATGAAGTATGTTGATACGGTGGTCTTTGACAAGACGGGGA
CTCTGACGGAGGGTAAGTTTGGGGTTTCAGAGGTGGTGGCGGTCGGAATTTCTGAGAAGGAGCTTTTAAGGCTTACTGCA
GGGGTTGAAGAACGCTCAGAGCATGTTATAGCTCGGGCTATAGTTGAGGAAGCTAGGGAAAAAGGGGTGAGCTTTCCAGA
GGTCAAAAACTTTAGGGCTGTACCAGGCAAAGGTGTAGTGGCTGAAGCTGAAGGGAAAGAGGTTGCGGTAGGAACGAGCC
TGCTTATGGAGGAGCTTAAGGCGGAGAAAGAAACAAAGATACTAAACAGAGTTAAAGAATTTGAATCCTATGGTAAAACG
GTGGTTCTTGTTGCTATAAATAGGAAGCTAACCGGTGCGATAGCCCTCTCTGACAAAATAAGGAGGGAGTCTTATGAGGC
TGTATCGGAGCTAAAGAGATTGGGTAAAAGAGTGGTTATGATAACGGGTGATTCCGAAGAAGTAGCCAGCTATGTGGCAC
GAGAACTGGGTATAGACGAATTCTTTGCAAGAGTTCTTCCCCATCAGAAGGCTCAGAAGGTGAAAGAACTCCAGTCAAAG
GGTAGAAAGGTGGCTATGGTGGGAGACGGAATAAACGATGCACCTGCCCTAGCTCAGGCGGATGTGGGTATTGCTATAGG
GAGTGGGACTGATGTGGCTATAGAAAGCGCAGGGATAATCCTTGTAAAGGACGATCCAAGGGATGTGGTAAGAGTAGTAA
GGCTTTCTTCAATAACTGTTAGAAAGATGTTTCAAAACCTCTTTTGGGCAACAAGCTACAACCTTTTTGCCATACCTTTG
GCTGCTGGTATAGGCTACAGATGGGGCATACTGCTTCCGCCGGCAGTGGGTGCCCTTCTCATGAGCTTGAGTACCCTGAT
AGTATCCGTAAATGCCCTTCTCATGAGGAGGTCCCTAGAATGA

Protein sequence :
MHPEVKRESPGKCPKCGMDLVPTEHPPRKHHHTMHMEEMKRKAIVSTVLTIPVVLYSKNIQNLLRFSMPEFPGSEWITPI
LSAIVFFYGGTFFLKGMAEELRLKKPGMMTLIGIAIWVAFIYSLSTLLLGGMEFFWELATLIVVMLWGHWIEMRSVLGAS
RAVEELAKLMPTKANLLKDGEIVEVHVSELKPGDIVLVKPGEKIPADGIVIEGLTHMNEAMLTGESKPVPKGVGDRVIGG
AINMEGSIKVKVEKTGEETYLSQVLKLVKEAQESKTKLQDMADRVAFYLTVIAIVVGSLAFLVWLYLKGDLQFAVERAVT
VMVIACPHALGLAIPLVVAISTSYSAKNGILVRNRLALETMKYVDTVVFDKTGTLTEGKFGVSEVVAVGISEKELLRLTA
GVEERSEHVIARAIVEEAREKGVSFPEVKNFRAVPGKGVVAEAEGKEVAVGTSLLMEELKAEKETKILNRVKEFESYGKT
VVLVAINRKLTGAIALSDKIRRESYEAVSELKRLGKRVVMITGDSEEVASYVARELGIDEFFARVLPHQKAQKVKELQSK
GRKVAMVGDGINDAPALAQADVGIAIGSGTDVAIESAGIILVKDDPRDVVRVVRLSSITVRKMFQNLFWATSYNLFAIPL
AAGIGYRWGILLPPAVGALLMSLSTLIVSVNALLMRRSLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 1e-90 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hydth_1794 YP_005512468.1 heavy metal translocating P-type ATPase BAC0629 Protein 1e-156 61
Hydth_1794 YP_005512468.1 heavy metal translocating P-type ATPase BAC0079 Protein 2e-115 45
Hydth_1794 YP_005512468.1 heavy metal translocating P-type ATPase BAC0101 Protein 8e-87 42
Hydth_1794 YP_005512468.1 heavy metal translocating P-type ATPase BAC0383 Protein 4e-94 41
Hydth_1794 YP_005512468.1 heavy metal translocating P-type ATPase BAC0183 Protein 8e-86 41