Gene Information

Name : Hydth_1763 (Hydth_1763)
Accession : YP_005512437.1
Strain : Hydrogenobacter thermophilus TK-6
Genome accession: NC_017161
Putative virulence/resistance : Resistance
Product : Arsenical pump membrane protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1617835 - 1619142 bp
Length : 1308 bp
Strand : +
Note : COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR000802; KEGG: saf:SULAZ_0803 arsenic efflux pump; PFAM: Arsenical pump membrane protein; SPTR: C1DUJ6 Arsenic efflux pump; PFAM: Arsenical pump membrane protein

DNA sequence :
ATGGAAAAGTTCTTGGCAGTAACCATATTCATCCTTTCGCTGGCTTTTGTTATAACTAAACCTAAAGGGATAGGTATAGG
CTGGTCCGCGTGGGCTGGTGCCATTGCTTGCCTTCTTCTGGGTATTGTGTCTATTGGAGATGTCCTGTATATTGCAAGCC
TGGTGTGGGATGCTACCCTAGCTTTTGTGTTTCTTGTGCTTATCTCCATAATCTTAGATAAAGCCGGATTTTTTGAATGG
ACAGCTCTAAAGGCAATAGGCTACGCTAAGGGGAACGGGCTTTTGCTTTTTGTATTCTTGATGCTCTTAGGAGCTTTTAT
CTCCGCCGTTTTTGCCAACGACGGAGCTGCTTTAATGCTTACCCCCATCATCTACTCAAAGATAAGGCATCTAAAACTTC
CTCAAAGGATGGTGCTTCCCTACATTATGGGAAGCGGTTTTATATCGGATAGCGCAAGCCTGCCCCTCGTTATCTCCAAT
TTAACTAATATAATAACCGCCCACTTTTTTAATATGGACTTTTGGCATTACGCCCTTTTGATGTTTTTACCTAACTTGGT
CTCCATCTTGACAAGTATATTAGTCCTTTATGTCTACTATAGAAAAGATATGATAAAGAGGTACGACACAGATGTGCTTG
AAGACCTCCCCCCAAAGTATGCGCTAAAGGACCCCTTTATCTTTAAGGTAGGTTGGTTTGTTATAATCGCTCTTGGTATT
GCCTTTTTGGCGTTGGAGTTATACCATATGGCTAAACTTCCTTACTCTGCTATTCTTGGAGCTGGTGCGCTAATTCTGTC
TTTGGCATCAATCAGACATCGTGTAGTGAAGATAGAGGAAGTCATAAGGTTTACACCCTGGAGCATAGTCTTTTTCTCTG
TAGGTATGTATGCTGTAGTTTACAGCCTGAAGAAGGTAAACATAACTAACTTTATAACGCATGTGGTATCTTACCTGTAT
CGTGTTGGAGAGTTCTATGCTCTTTTGGGTACCGGTCTTTTGTCCGCCTTTATGTCCGCAGTTATGAACAATCTGCCCAC
CGTTATGTTAGTGAACATATCTATACAAGATGCGCATCTTCCAGAGAGATTTACACAATTTCTTGCCCTTGCCAACTTAG
TAGGTACCAACATAGGACCAAAACTCACACCCATAGGCTCTTTGGCTACCCTCCTTTGGCTACATGTTTTGGAACACAAA
GGCATAAAGATCACTTGGGGTTATTACATAAAAGCGGGTTTTGTTTTGACACTTCCCGTACTACTTGCGGTGCTTTTAAC
TCTGTGCTTTATTTATTACCTAGTATGA

Protein sequence :
MEKFLAVTIFILSLAFVITKPKGIGIGWSAWAGAIACLLLGIVSIGDVLYIASLVWDATLAFVFLVLISIILDKAGFFEW
TALKAIGYAKGNGLLLFVFLMLLGAFISAVFANDGAALMLTPIIYSKIRHLKLPQRMVLPYIMGSGFISDSASLPLVISN
LTNIITAHFFNMDFWHYALLMFLPNLVSILTSILVLYVYYRKDMIKRYDTDVLEDLPPKYALKDPFIFKVGWFVIIALGI
AFLALELYHMAKLPYSAILGAGALILSLASIRHRVVKIEEVIRFTPWSIVFFSVGMYAVVYSLKKVNITNFITHVVSYLY
RVGEFYALLGTGLLSAFMSAVMNNLPTVMLVNISIQDAHLPERFTQFLALANLVGTNIGPKLTPIGSLATLLWLHVLEHK
GIKITWGYYIKAGFVLTLPVLLAVLLTLCFIYYLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 8e-75 47
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 7e-73 46
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-74 46
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 8e-65 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Hydth_1763 YP_005512437.1 Arsenical pump membrane protein BAC0574 Protein 2e-75 47
Hydth_1763 YP_005512437.1 Arsenical pump membrane protein BAC0575 Protein 2e-74 46
Hydth_1763 YP_005512437.1 Arsenical pump membrane protein BAC0578 Protein 4e-66 45
Hydth_1763 YP_005512437.1 Arsenical pump membrane protein BAC0576 Protein 1e-65 45
Hydth_1763 YP_005512437.1 Arsenical pump membrane protein BAC0031 Protein 4e-63 44
Hydth_1763 YP_005512437.1 Arsenical pump membrane protein BAC0577 Protein 7e-66 42