Gene Information

Name : YPD8_0228 (YPD8_0228)
Accession : YP_005507311.1
Strain : Yersinia pestis D182038
Genome accession: NC_017160
Putative virulence/resistance : Virulence
Product : two-component sensor/regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 254769 - 257588 bp
Length : 2820 bp
Strand : -
Note : -

DNA sequence :
ATGGGCAAAGCATCATCACTTGTCACTCGATTGACATTATTAATGGGCGTCACACTAACTGTTATTTGGTTAATATTAAT
CGCAACAACGGCATTCTTTTCATATGAAAATACACGTCAAATATTAATCAATGAGTTAACACATATGGCATCGATGCGGG
CGGACTTAAGTAATCACCAGTTTGAAGGAGCTGAACGTGATGCCGCCTCGTTAATAAGCCGACGAGAAAGCCTCCAGAGC
ACCTCACCGTTGCCTGAAATATCGATAAAACATTATGATAGCTACTATATTCCCTTTAATCTGGATAGCTGTAATATTAA
CCAACATAAAAATGATCTGTGGATAATTCAAGCGTATGGCACCGCCGGACAAACTTATTATCTCGACAGTTTTATTATCA
AACAAAAAGAGGGGATTGTGTTATTCCCACCCCAAAAATCATCGAGTGATTACCTAAATCAACGGCGCAAAGATTTACTT
TTGCTCCCCAAATTTCCTACTCACAATAATATCTATTGGGGAGCCCCCACCTATACGCCTCAAGGTGGCTGGCATGTTTC
TGTCGCGGTGTGTGATAAAGTGGGCACCTTAGCTGGCTTCGCCTTAAAACTGAATGATCTCATCGCCTATAATCACCCTG
TCGAGCAAAGAGACATTAATTTATTGTTGGATAAGAATGGTGAATTATTGCCTATTTCCCAGCAAGCAACATCATCAAAT
CAACTGCATGAAATTCTTAACCAACTCAAAAACAGTAAATTACACGATGGCTGGCAGCAAACTCCCGACTATTTGGTATT
ACGCACCCAATTGAAAGGGCCGGGTTGGCAGCAATTAGTTATTTATCCGCGAATGGGCTTTGCCTGGGAGGCACTGAAAC
CCGCCTTATATCAACTCCCTTTCGCTCTGGCTATTTTACTGTTGCTCACGTCAGTACTGTCACTGCTGCTGCGATATTAT
CTGGCGATCCCTTTGTGGAATTTCATCAATATCATTGGCGCTACCGGGCCACAGGCAATGGAACCCCGACTTCCCATAAA
CCGAATAGATGAATTAGGGCATATTGCCCGCGCTTATAACAACTTACTGGATACGTTGAACGAACAATATGACACCTTAG
AAATGAAAGTGAAGGAGCGCACTCTGGCTCTGGCGGAAGCCAAGCGAGCGGCTGAGCAGGCTAACCGCCGTAAAAGCGAC
CATCTGACCACGATCAGCCATGAAATCCGTACACCGCTCAACGGGGCGTTGGGGGCGGTTGAATTATTACAAAATACACC
ACTGGATGCTGGCCAAATGAGGTTAGCGGAAACGGCCCACCAATGTTCGTTGTCACTGCTCGCGATCATTAACAACCTGT
TAGATTTTTCACGTATTGAATCAGGGCAGATGACACTGTCGCTGGAGAAAACGGCCCTACTGCCTTTACTGGATCAGGCG
ATGTTAACCATTCATAGCCAGGCACTGAGTAAGTCATTAGCGCTGTCCACGTTTATCAGTGCCAATATCCCGCTGGAACT
TGAGCTGGATACACTGCGCTTAAGACAGATTCTGGTTAATTTATTAGGTAATGCCGTTAAATTCACACCACAGGGCCGTA
TTCAACTCAGGGTCAGGCGTCAAAACCAAACGCTTTGTTTTACCGTTGAGGACACCGGTTGTGGTATTGACGTGCAACAC
CAACAAACAATATTCCAACCTTTTATGCAGACCAGTGACCATGAACAAGGAACGGGTTTGGGGCTGGCTATCGCAGATAA
TCTGGCCAAAATGATGGGAGGGCACCTGACAGTATTCAGTGAACCGGGTCAAGGTAGCTGTTTTTCATTATGCCTCCCCT
TCAATGCAATCACCCCGCCAATGCCTTTTCATGGCGAGCTATTCGCACCACAACGCTTACACGCCCAATTATCAGCCTGG
GGCATGACCTGCCAGCCAGAATTAGCTAATCAGCCATCACGGCACTTTGTGGATAACGCATTGTGTTACTTACCCGGCCG
GTTATACGCCAAGCTGAAACAATATCTACAAGGTGCTGAGACTGAAGCGCTAAAGAGCCTTCCGCTGCAACCTTGGCAGA
TGCACATTCTATTGGTTGATGACTCCGAAACTAATCGCGATATTACCGGAATGATGTTGCAGCAACTGGGGCATCAGGTC
ACGCGGGCAGACAGTGGCACAACCGCATTGGCGATTGGCCGCCAACACCGTTTCGATTTAGTGCTAATGGATATTCGAAT
GCCTGTCCTGGACGGGCTGGCCACCACAGCACGCTGGCGTCATGATCCGGCGAACATTGATAGCCACTGCATGATCACCG
CCCTGAGCGCCAATGCCAGCCCGGATGAGCAAATCAAAACCAGTCAGGCGGGGATGAATCACTACCTTTCCAAGCCTGTC
ACCCTCGGCCAATTGGCTGAAATGTTAGATCTGACCGCACAATTCCAGCTTGAGCGTGGGGTCGATCTATCACCACAACT
CTCCGAGCCTCAGCCATTACTGGATCTCGCGGACAGCGCGTTGTCCCTGAAACTTTATCAATCACTGCAAGTATTAATTC
AACAGGCCAAAGACGCTATTGAGAACTTGCCCGTATTATCCCATACGCTTCACACCATAAAAGGCTGTGCCGGGCAAGCT
GGGCTAATTGAATTACAAGATGCGGTCATTCAATTAGAACACGCTCTCGATACTCATGAAACGCTGACACAGCAAGAGAT
CATTCAACTTGATGAAATAATTCATGTGCTGCTACAGCCCCCCACTACCTGCGAATCCACGTTTATCATCAGCCAGGGCC
AGTCCCTTATGGTTAAATAA

Protein sequence :
MGKASSLVTRLTLLMGVTLTVIWLILIATTAFFSYENTRQILINELTHMASMRADLSNHQFEGAERDAASLISRRESLQS
TSPLPEISIKHYDSYYIPFNLDSCNINQHKNDLWIIQAYGTAGQTYYLDSFIIKQKEGIVLFPPQKSSSDYLNQRRKDLL
LLPKFPTHNNIYWGAPTYTPQGGWHVSVAVCDKVGTLAGFALKLNDLIAYNHPVEQRDINLLLDKNGELLPISQQATSSN
QLHEILNQLKNSKLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRMGFAWEALKPALYQLPFALAILLLLTSVLSLLLRYY
LAIPLWNFINIIGATGPQAMEPRLPINRIDELGHIARAYNNLLDTLNEQYDTLEMKVKERTLALAEAKRAAEQANRRKSD
HLTTISHEIRTPLNGALGAVELLQNTPLDAGQMRLAETAHQCSLSLLAIINNLLDFSRIESGQMTLSLEKTALLPLLDQA
MLTIHSQALSKSLALSTFISANIPLELELDTLRLRQILVNLLGNAVKFTPQGRIQLRVRRQNQTLCFTVEDTGCGIDVQH
QQTIFQPFMQTSDHEQGTGLGLAIADNLAKMMGGHLTVFSEPGQGSCFSLCLPFNAITPPMPFHGELFAPQRLHAQLSAW
GMTCQPELANQPSRHFVDNALCYLPGRLYAKLKQYLQGAETEALKSLPLQPWQMHILLVDDSETNRDITGMMLQQLGHQV
TRADSGTTALAIGRQHRFDLVLMDIRMPVLDGLATTARWRHDPANIDSHCMITALSANASPDEQIKTSQAGMNHYLSKPV
TLGQLAEMLDLTAQFQLERGVDLSPQLSEPQPLLDLADSALSLKLYQSLQVLIQQAKDAIENLPVLSHTLHTIKGCAGQA
GLIELQDAVIQLEHALDTHETLTQQEIIQLDEIIHVLLQPPTTCESTFIISQGQSLMVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0256 YP_002345336.1 two-component sensor/regulator Not tested Not named Protein 0.0 100
spiR AAC44299.1 SpiR Virulence SPI-2 Protein 3e-145 47
ssrA NP_805063.1 two-component sensor kinase Virulence SPI-2 Protein 2e-153 45
ssrA NP_456136.1 putative two-component sensor kinase Virulence SPI-2 Protein 7e-153 45
ssrA YP_216400.1 secretion system regulator:sensor component Virulence SPI-2 Protein 6e-153 45
ssrA NP_460357.1 sensor kinase Virulence SPI-2 Protein 4e-152 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPD8_0228 YP_005507311.1 two-component sensor/regulator VFG0493 Protein 2e-152 45