Gene Information

Name : irp2 (YPD4_0680)
Accession : YP_005503892.1
Strain : Yersinia pestis D106004
Genome accession: NC_017154
Putative virulence/resistance : Virulence
Product : HMWP2 nonribosomal peptide synthetase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 848500 - 854958 bp
Length : 6459 bp
Strand : -
Note : -

DNA sequence :
TTGGCGACGGCGCGCCAGCTTGCCGAGGTCTTGTCACAGCATACGGCGCTTGCTCGGGCGGTTGTCGCTGCGTGGCGCAC
TAAACGTAGCCATCATTTTCCCATCCGTGCCTTGATTCAATATCACTCATTAAGTGATTTGATCGCACAGTTACATCAAG
TCACCGGCGAGAAAAGTGATCCCCGCTGTCGCTTTGAAAAGGCGCAATCGCCCAAACAATGGTTGGCGGGAGGGGCTTTT
GACTGGGCAGCAGTCACCCCCTCTGAAGGGGCCGTTAGTGCTGAGGTGTTGGCGCTTTTGCCTCTTTATCCTTTTACTCG
CCAGCGCTATTGGGCTGAAGGTCTGCTGGCAGAGAGTACCCCCTTATCTTCCCCTTCGGTTATTGCCCATCCCCTTGATT
TTTCATTTGTGCGCACTTGGGTGGCAGAGACACTCGCTATCGCGTCTGGAGCGTTATCTGATGAGGATGATTTGCTGAGT
TTAGGTTTAGATTCTTTGCAGATGTTGGATCTGGTGGATGAGTGTAAAAAACGCCATATCACTTTGACGTTGGCAAGGTT
GTTTGAAAAAACAACCCTGGGAGCATGGGAACAGTATTGGGACAGTATTTGTAGAAGCGGTGTCTGCGGGGAGAGTGTCA
GTGCGGTTACCCCACTCACAGAAGAGCAAACCACGGATGAGTACTGGCAGGGGGAGCCTTTTGTGCTTACCCCTGTGCAG
CAAGCCTATTGGCAAGGGCGTCAGAAGGGGCAAACGTTGGGGCAGGTTGCCTGTCAGGTTTATCTGGAGTTGGATTGCCC
GTCGTTAGCGGATGAACGTCTTCATCAGGCGGTGACGCAATTATTCCACCGTCATGAGCTTTTGCGTATGCGTATTAACG
AGCAAGGGATGGGGGTTATCCAGGAAATCGAGCCGGTGACGGTAACGCAATATCACTGGGATCAGCTCTCTGCAAGGGCT
GGTGCAAAGGAGCGCTACGCGCTACGGGCGCGTTTATCCCATCGTATGGCTGATTTAACTGACGAGAGTGGGTTCCAATT
GATTGCCAGCCATGATGGGCAAAACACCCGTTTGCACATTAATGTGGACATGGTGATTGCTGATGCCATGAGTTTGCAAA
TTCTGTTGGAGGAGCTAGGGCTGCTCCTTTCGTCGCAGAATACGCCATTTGCACCGTTGGATTACCACTTCCCGCAATAT
TTGTTGGAGCAAAAATCAACACCATCAACGGGTGAGAGCGAAGCTTACTGGCAACAACGGTTAATCGCAGGTTTACCGTT
AGCCCCGCAACTGCCATTGGCAATAAAACCGGAGCAGATAGATAAACCTATTTTCCAACACCGTGAGTGGCGTTTAGCGT
CAGAACATTGGGCTAAATTACAACAAATAGCCCGCCAACATAGGTTAACGCCCTCCATGTTATTGGCGGGTTGTTTTGCT
GAAACATTACGGGGTTGGGCGAAATTGCCTGACTTTTCGCTGAACTTAACGATTTTTAACCGTCGTGGCGCACATCCACA
ATTGGCAAAATTGGTCGCTGATTTTACGTCCTTGCTCATACTGGCATGTGAGGTTAAAGAAAACGAAAGTTTACTGGATC
ATTTCCGCAGGCTGAATCAGCAGTTTATGGTTGATCTGGATCATGGGGATTACAGCGCAGTGCACGTGTTGCGTCAGTGG
TCTCAACAGCGGGGCGAACAGGTTACTCTGCCGGTTGTCTTCACCAGTAATCTTGGGCGTGAATTGCTCGGGGAAAATGC
ACCAGGGGCGCTGCATTATTTGGTTTCTCAGACACCACAAGTGTGGCTAGACTGCCAGGTGATGGAGTATCAGAAAGCCC
TGTTGATCAGTTGGGATACCGTGGACGCACTCTTCCCCGAAGGGATGCTTGATCAGATGTTTGCTTTTATGCAGCAGCTT
CTTCAATCCATTGTCGAAAATGAGCAAGTCTTACAGTCACCTGTTCAGGCGTATGTGGATGACAAGGTGCTGGCGCATCG
CCAACAGCCGTTATCGGGTGTCCACGGGGTGCCTTTTGAGGCCAAAACCCTGCATCAGGGCTTTTGGCAGCAAGTCGCAT
TGGTCCCGAATAACATTGCTGTCATCAATGCCTCCGGTGTCTTGACGTATAGGGAAATGGCAATACGAGTCGGCGATTTG
GCGGGGTACTTACAGCAGCGCATTGCACGACAGGGCCATGTGGGTATTTGTTTACCTAAAGGGATTGAGCAAGTGATCGC
GGTGCTGGCGGTATTGTCCATTGGGGCGGTGTATGTGCCGTTGGATATTACCGCGCCCTCCGAACGCTTACAGCAACTGA
TCGCGCAGGCGGATATTGGCGTATTGATTAGCGATCACGAGATATCCGCTAACTGCGACACAGTGAATATCAACATAACA
GGCGGTTTTCCATCGCCTTTTACCCCGTCTGTTTTTACCTCATCTGCTGCTGCGCCCTCTATTTTTGTACCCTCTATTTT
TGTACAACCTGATGAGCCAGCCTATCTGATTTTTACCTCAGGCTCGACGGGGGTGCCTAAAGCGGTGGTGGTGACACATC
AGGCTGCAATGAATACGATTGATGAGATTAATCGCCGCTATGTTGATGATGGGAAGATCATCTTGTTCGCACTCTCGGCA
TTAAATTTCGATCTCTCGGTTTATGATATTTTTGGTCCTTTGTCTGTCGGCGGCTCCCTGGTATTGCCCAACGCGGGCGA
TGAAAAAGAAGCTAAACAGTGGCTGTCAGCACTGCATCAACATCAAGTGACACATTGGAACAGTGTTCCTGCCTTATTTG
AAATGCTGCTGATCGCCGCTGAGCAAGGTACGCAAGCTTTGCCTCGTTCGTTACAACAGGTGTTGTTGTCGGGGGATTGG
ATTGGGTTAGACCTTCTCCCCAGGCTGAGAGCGCTTGGTAGCCAAGCACGTTTCACCACGCTGGGCGGCGCCACAGAAGC
GGCCATTTGGTCTAATGCGCTGGATATCGCGGTGATCCCTGAAGAGTGGGTATCCATACCTTATGGTTATCCACTGGCCC
ATCAATATTATCGTGTCGTTGACCAGGCTGGCAGAGATTGCCCTGATTGGGTGACAGGGGAACTGTGGATTGGCGGTAGG
GGAGTGGCATTAGGTTATTACCGGGAGCCAGAAAAAACGGCGGCGCAATTTGTCTCTGTTCATCGCGCGGGGTTTTATCG
AACAGGCGATTATGGTCGCTTCTGGCCTAATGGGTGTCTGGAGTTTTTGGGGCGACAGGATAGACAAATAAAACTGCATG
GTTATCGCATTGAATTAGCGGAAATTGAAGCTGTCGCAGAGCATCTGGCAACGATTAAACGTGCTGTGGTTTTATATTTG
GATCAGCCACAAAAGCATTTATACCTGTTTGTTGAGCCTCAGAATCAGGTATCCACTCTCTTCTCCGCAACCGTTGATGA
TGTATTACCTGAAACCAGACTTGTAACGGATATTCGTGAACAAGAAAACACGATAACCGCTTTTCTGTTATGCCATGTGC
TCAGCAATGTTCTCAAGCTCGATCTGGCAGAGTATCAGTCTACGCAAGTATTGCAGGAAAAAGGGGGGATTAGCGAAGCC
TACCAACCGCTATTTTTAGCCTGGCTCCATTGGTTGGTTGAGCAAGGGGTTTTACTTTCTCGCGATGACCAGTTTAAAAC
CACAGGAATTCAGCCCGTACGCCCTGAGGTGACTGAACCACACCTGTTACCGCTCTTGATGACGTTAGAGCAAAAAGCGT
CATGGATTGGCGAGGTGGTGACTGGGCGGGGAAATCCACTGTTATTGTTGGACGACACGCTCCTGTCGCCAGAAATTTTA
GTCGCCAATACACATGATGCCCAAGTGGTTATTGATGTGCTATGTCAGCGCATTGCTCGTTTATCTCGGCAATTACAACG
GCCTGTTAATGTCACCGAATTGAATGGGCGAACGGGGCTGTTTGCCAGCCGGGTATTGAGCCGGTTGGGAACTGAGGTGC
TGAGTTACTGTTTGTTGGAATCTGCAAATTCATTGCGTCAACACGCAAAGTATCGTTTATCTGGCTATTCCCATGAAACA
GATGTGATTGCAACACCCGATGAACAGCAACAACTTGCCGATATTCTGATCGTCAATAATTCACTACACCGATTTGATGC
CCTGCCTGAGGGGATTGCCATGCTGCAATCCCTTTGCCACGGAGGGACGGAAATTGTCCTGTTTGAAAGCCTGGCACTAA
GCCCACTGTCGCTATTAACGGTGTTGTTGTTACAACATCCCAATGGTTTTAGGGATCAACGGCAAGGGGCACTTTCGCCG
CTCTTGGATTTACCCGCCTGGCAGTCGTTGTTAACGGATTCAGGTATTGCCATCCAGCAACTCAGTATTATTGAACCGTA
TTCTGCACTCTTTGTCTGTCAACCACAGATAACGAAAGTGCCCGTTTCGCGTGAACAGATAAAGCAACATTTACAGCAAC
ATTTACCCGCCTATATGGTGCCATCGTCTATCACGGTACTGGAGACATTGCCACTGACACCGAACGGCAAAATTGACCGG
ACATCGTTATATAAACAGGCCGTTGAGTATGGGCAGCTAAGCCATGATGGTGAAGCGCCTCGCGTGTTATCTGCCCAACA
GAAGCCGCCAGATGAACGGGAACGGTCTGATAAACGAGAACTGTCTGATAAAAAAGAACAGTGCGTCGCTCGCCTTTGGC
AGCAAGTGTTAGGGGTTACGCCGCAATCAGATAGCAACTTTTTCCTGTGTGGTGGTGATAGCCTTCATGCCACGCGCATC
GTGGCCTTGTTGGAAAAAGAGGGCACGGTTGGCGTGCCATTGTCTCAGGTGTTTTTATTGCCGGTGTTAAGGGATTTTGC
TCACAGTCTGGCGTTCCGCCATGCGCCTGTACAGGAGGCGCAATTAGTTCATTGTGCCGCCCAACGTTATTCGCCCTTTG
AGCTAACCGATGTGCAGCGAGCATATTTAATGGGGCGGCAATCGGGGTTCCCACTGGGTGGCGTGGCAACGCACTATTAT
CAGGAATACGAGTATCAGGAATACGAATATCAGGAAAATGAAATTTATCAGGAACATGAAAGCCATCAGCAATATAAAGG
CACACCGTTTGACCGGGAACGATTAGAGCGGGCCTTAACTCTGCTGGTAGCTCGTCATGATGCGTTGCGTATTGTGTTTG
ATGAACAGGGTACACAGCGTGTGTTACCCCATCAACCGTCCCCGGCGCTTCAGGTTATTCATTGCGGTGCTGTGGAGTGG
GAAACCGTGACGGCGACTCAACGGGATCGGTTGTCACATTATGTCTCTGAACCGACCCAATGGCCGTTGTTCCACGCGAC
CTTAATTCAGTCTGATGAGGGTAGAAATCGTTTTTGCCTTGGGCTGGATAATCTGGTGTTAGACGGTTTGAGTATGCAGA
TCTTCTTTAAAGAGTTGGCTGTCTTGTATGAGGACCATACCGCCACGCTACCCTCCGTGGAGATTGGTTTCCGCGATTAT
CTGCTCGCTGAATCATCGTCACCTCATCGCCAAGTCTCTGAGGATTATTGGCGAGAAAGTCTCCCAATGTTACCGGATGC
ACCGCGCTTGCCATTGGTGTGCGATCCCGCCTTAGTGGGCACGCCTAAATTTAAGCGTTGGCAAGCTGTCTTGTCGGCCT
CTGATTGGCAGATGTTATTGCATAAAGCCAAACAGCATCAAATTACACCCTCTTGCTTACTCCTGACTTGCTATGCCCAA
GTTTTGGCGAAGTGGTCTGAATCAGCATCACTCACCATCAATGTCACCTTGTTTGATCGCAAACCTTGTCATCCAGATAT
TAACCATATTATGGGCGATTTTACTTCTCTGCTCTTATTAGGTTGTCGACAAGAGAAAGGGGAAGGGTGGTTGGCAACGG
CTCAGCGTATTCAGCAACAGCTATGGCGAGATCTGGAGCACCGTGAAGTTTCCGCCGTCTGGGTGCTCAGGGAGTTAAAT
CGCCAGCGGGGAACAACCCATATTCACATGCCGGTGGTGTTTACCAGTGCCTTGGGCGCACAAGTGGATGGTTACCCTGA
CAGCGCATTCCAAGCCCCTCTTTGGGGGATTTCTCAGACACCGCAATTGTGGATTGACCATCAGGTTTTCGAACGTGATG
GCGAATTGCATTTTAACTGGGATGTCGTTGAGGCTTTATTTCCAGCTGGCGTGATTGACGCCATGTTCGCCGCTTACTGT
CAGTTGTTGGAAAAACTTTGTGTCACAGAGCACTGGCATGACAGCGTTGAGATTGCGTTACCTGCGCCGCAGCAGCAGAG
CCGGCAGAGGGTAAATGCGACCCATCAAGCGATGATATTTTCGCCTATGCACTGTCGGGTCGCGCACGCTATGGCGGCAT
ACGCCCAGCAGACCGCGTTAATTTGGGGGGGGCAGCCGCCTCAGCTATCAACAACTTGA

Protein sequence :
MATARQLAEVLSQHTALARAVVAAWRTKRSHHFPIRALIQYHSLSDLIAQLHQVTGEKSDPRCRFEKAQSPKQWLAGGAF
DWAAVTPSEGAVSAEVLALLPLYPFTRQRYWAEGLLAESTPLSSPSVIAHPLDFSFVRTWVAETLAIASGALSDEDDLLS
LGLDSLQMLDLVDECKKRHITLTLARLFEKTTLGAWEQYWDSICRSGVCGESVSAVTPLTEEQTTDEYWQGEPFVLTPVQ
QAYWQGRQKGQTLGQVACQVYLELDCPSLADERLHQAVTQLFHRHELLRMRINEQGMGVIQEIEPVTVTQYHWDQLSARA
GAKERYALRARLSHRMADLTDESGFQLIASHDGQNTRLHINVDMVIADAMSLQILLEELGLLLSSQNTPFAPLDYHFPQY
LLEQKSTPSTGESEAYWQQRLIAGLPLAPQLPLAIKPEQIDKPIFQHREWRLASEHWAKLQQIARQHRLTPSMLLAGCFA
ETLRGWAKLPDFSLNLTIFNRRGAHPQLAKLVADFTSLLILACEVKENESLLDHFRRLNQQFMVDLDHGDYSAVHVLRQW
SQQRGEQVTLPVVFTSNLGRELLGENAPGALHYLVSQTPQVWLDCQVMEYQKALLISWDTVDALFPEGMLDQMFAFMQQL
LQSIVENEQVLQSPVQAYVDDKVLAHRQQPLSGVHGVPFEAKTLHQGFWQQVALVPNNIAVINASGVLTYREMAIRVGDL
AGYLQQRIARQGHVGICLPKGIEQVIAVLAVLSIGAVYVPLDITAPSERLQQLIAQADIGVLISDHEISANCDTVNINIT
GGFPSPFTPSVFTSSAAAPSIFVPSIFVQPDEPAYLIFTSGSTGVPKAVVVTHQAAMNTIDEINRRYVDDGKIILFALSA
LNFDLSVYDIFGPLSVGGSLVLPNAGDEKEAKQWLSALHQHQVTHWNSVPALFEMLLIAAEQGTQALPRSLQQVLLSGDW
IGLDLLPRLRALGSQARFTTLGGATEAAIWSNALDIAVIPEEWVSIPYGYPLAHQYYRVVDQAGRDCPDWVTGELWIGGR
GVALGYYREPEKTAAQFVSVHRAGFYRTGDYGRFWPNGCLEFLGRQDRQIKLHGYRIELAEIEAVAEHLATIKRAVVLYL
DQPQKHLYLFVEPQNQVSTLFSATVDDVLPETRLVTDIREQENTITAFLLCHVLSNVLKLDLAEYQSTQVLQEKGGISEA
YQPLFLAWLHWLVEQGVLLSRDDQFKTTGIQPVRPEVTEPHLLPLLMTLEQKASWIGEVVTGRGNPLLLLDDTLLSPEIL
VANTHDAQVVIDVLCQRIARLSRQLQRPVNVTELNGRTGLFASRVLSRLGTEVLSYCLLESANSLRQHAKYRLSGYSHET
DVIATPDEQQQLADILIVNNSLHRFDALPEGIAMLQSLCHGGTEIVLFESLALSPLSLLTVLLLQHPNGFRDQRQGALSP
LLDLPAWQSLLTDSGIAIQQLSIIEPYSALFVCQPQITKVPVSREQIKQHLQQHLPAYMVPSSITVLETLPLTPNGKIDR
TSLYKQAVEYGQLSHDGEAPRVLSAQQKPPDERERSDKRELSDKKEQCVARLWQQVLGVTPQSDSNFFLCGGDSLHATRI
VALLEKEGTVGVPLSQVFLLPVLRDFAHSLAFRHAPVQEAQLVHCAAQRYSPFELTDVQRAYLMGRQSGFPLGGVATHYY
QEYEYQEYEYQENEIYQEHESHQQYKGTPFDRERLERALTLLVARHDALRIVFDEQGTQRVLPHQPSPALQVIHCGAVEW
ETVTATQRDRLSHYVSEPTQWPLFHATLIQSDEGRNRFCLGLDNLVLDGLSMQIFFKELAVLYEDHTATLPSVEIGFRDY
LLAESSSPHRQVSEDYWRESLPMLPDAPRLPLVCDPALVGTPKFKRWQAVLSASDWQMLLHKAKQHQITPSCLLLTCYAQ
VLAKWSESASLTINVTLFDRKPCHPDINHIMGDFTSLLLLGCRQEKGEGWLATAQRIQQQLWRDLEHREVSAVWVLRELN
RQRGTTHIHMPVVFTSALGAQVDGYPDSAFQAPLWGISQTPQLWIDHQVFERDGELHFNWDVVEALFPAGVIDAMFAAYC
QLLEKLCVTEHWHDSVEIALPAPQQQSRQRVNATHQAMIFSPMHCRVAHAMAAYAQQTALIWGGQPPQLSTT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0778 YP_002345834.1 siderophore biosysnthesis protein Virulence HPI-2 Protein 0.0 99