Gene Information

Name : YPD4_0224 (YPD4_0224)
Accession : YP_005503436.1
Strain : Yersinia pestis D106004
Genome accession: NC_017154
Putative virulence/resistance : Virulence
Product : type III secretion protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 255724 - 257295 bp
Length : 1572 bp
Strand : +
Note : -

DNA sequence :
TTGATAGTCGGTTTACGCCAAAAACCGTATTTAAATTTAAGAAATTATAAGTGGATGTCGCTAATCTATATCATGAGAAA
AATAACGGGTCTGATATTACTTTTTTTTGCCACATTGTTGCCTTATGGGAAATTTTCTTATGTAAAAGCGATTCCTTGGC
AAGGCGAGCCTTTTTTTATTTATAGCCGAGGCATGACAGTTTCTGAATTATTAAAAGATTTGGGGATGAATTACGGTATT
CCTGTGGTGATCAGTTCGGAAATAAACGAGCACTTTACTGGAAAGATTAGGGATAAGACACCTGAAAAAATCCTATCGGA
GTTGGCTGGGCGATATAATATAACGTGGTATTACGATGGTGAAACACTCTATTTTTACCCAGTTCAATCAATCAAGCGGG
AGTTTATATCCCCCGATGGTCTGGCTGCCAATACGTTAGTTAAATATCTCCAGCGCGGTGACGTGCTGGCGGGGAAAAAC
TGTGCCATAAAAGCGATCCCCCACCTTGATACCCTTGAGGTCAAGGGAGTGCCTATCTGCATCGAACGCGTAAAGTCAGT
AAGCAAAATGCTTTCTGAGCAAGTTCGTCACCAAAACCAAAATAAAGAAACAGTGAAAGTTTTCCCGCTGAAATATGCTT
CAGCAGCGGATTCAGATTATCAGTACCGAGATCAAAACGTCAGATTACCGGGGTTGGTCAGTGTGTTACGTGAGTTGAAC
CAAGGGAATAATTTGCCTTTGGCGGGCGGTAACCAACCAGATGGAAATCAAGCAAGCTCACCGGTGTTTTCGGCTGATCC
TCGGCAAAATGCCGTCATTATTCGCGATCGCCAGGCTAATATGCCGATTTATCGCAGCTTGATTACCCAACTGGATCAGC
GGCCAATTCAGATAGAAATTTCTGTCACTATTATTGATGTTGATGCGGGAGATATCAGCCAACTGGGTGTTGATTGGTCT
GCATCTGCTTCTATTGGTGGAACGGGGGTCTCATTTAATAGCACCTTCGCCAAGAATAATGCTGAAGGCTTTTCTACCGT
GATTGGTGATACGGGGAACTTTATGGTTCGTCTGAATGCGTTACAAAAAAATTCACGAGCCAGAATTTTATCTCAACCTT
CAGTGGTGACCCTGAACAATATTCAGGCGGTACTGGATAAAAACGTGACGTTTTATACCAAGCTGCAAGGTGAGAAAGTG
GCCAAACTTGAATCTGTCACTTCAGGGTCATTACTGCGAGTGACGCCAAGAATGATCGAGACCGAAGGGGTACAAGAGGT
TTTACTGAATCTCAATATTCAGGATGGTCAGCAGCAAGCTTCTACCAATAGTAATGAGCCATTACCCGAAATACGAAACT
CAGATATTTCGACGCAGGCCACGCTACAGGTTGGACAAAGTTTACTCTTGGGCGGATTTATTCAGGACACGCAGATTGAG
TCACAAAATAAAATTCCTTTACTGGGCGATATTCCGCTATTAGGTGGGTTGTTCCGTAGTACAGATAAACAATCTCACAG
CGTGGTCAGACTCTTCCTGATCAAGGCCGTTCCGGTTAATGCAGGGGAATAA

Protein sequence :
MIVGLRQKPYLNLRNYKWMSLIYIMRKITGLILLFFATLLPYGKFSYVKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGI
PVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKN
CAIKAIPHLDTLEVKGVPICIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELN
QGNNLPLAGGNQPDGNQASSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWS
ASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKV
AKLESVTSGSLLRVTPRMIETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIE
SQNKIPLLGDIPLLGGLFRSTDKQSHSVVRLFLIKAVPVNAGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0257 YP_002345337.1 type III secretion protein Virulence Not named Protein 0.0 100
spiA AAC44301.1 SpiA Virulence SPI-2 Protein 1e-117 54
ssaC NP_460359.1 outer membrane secretin precursor Virulence SPI-2 Protein 2e-117 54
ssaC YP_216402.1 secretion system apparatus protein SsaC Virulence SPI-2 Protein 6e-117 53
spiA NP_456134.1 putative outer membrane secretory protein Virulence SPI-2 Protein 5e-117 53
spiA NP_805065.1 outer membrane secretory protein Virulence SPI-2 Protein 5e-117 53
escC CAI43881.1 EscC protein Virulence LEE Protein 8e-108 49
escC AAC38377.1 EscC Virulence LEE Protein 1e-106 49
escC YP_003223482.1 T3SS structure protein EscC Virulence LEE Protein 1e-107 49
escC YP_003232146.1 T3SS structure protein EscC Virulence LEE Protein 1e-107 49
escC AAK26708.1 EscC Virulence LEE Protein 8e-108 49
escC AAL57535.1 EscC Virulence LEE Protein 8e-108 49
escC CAC81855.1 EscC protein Virulence LEE II Protein 8e-108 49
escC YP_003236095.1 T3SS structure protein EscC Virulence LEE Protein 4e-107 49
escC NP_290275.1 hypothetical protein Virulence LEE Protein 3e-107 49
ECs4575 NP_312602.1 EscC Virulence LEE Protein 3e-107 49
escC AAC31520.1 L0041 Virulence LEE Protein 2e-107 49
escC ACU09465.1 type III secretion outer membrane pore YscC/HrcC family Virulence LEE Protein 2e-107 49
escC AFO66299.1 putative type III complex subunit Virulence SESS LEE Protein 2e-109 49
escC AFO66408.1 putative type III complex subunit Virulence SESS LEE Protein 2e-109 49
unnamed AAL06362.1 EscC Virulence LEE Protein 1e-107 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPD4_0224 YP_005503436.1 type III secretion protein VFG0495 Protein 7e-118 54
YPD4_0224 YP_005503436.1 type III secretion protein VFG0723 Protein 8e-107 49
YPD4_0224 YP_005503436.1 type III secretion protein VFG0819 Protein 1e-107 49