Gene Information

Name : Spiaf_1064 (Spiaf_1064)
Accession : YP_005474858.1
Strain : Spirochaeta africana DSM 8902
Genome accession: NC_017098
Putative virulence/resistance : Virulence
Product : chaperone ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1228836 - 1231352 bp
Length : 2517 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA)

DNA sequence :
ATGTTTAAGGGTTTGACACAACGCGCCCAGAAGGTTCTTACCATACTGGCACAGGACGAAGCCAAGCGATTTCACGCCGA
TCAGCTGCTGCCGGAGCACATAATGACCGCTCTGTTGAAAGAGGGCGGCGGTCTGGGCTACAAGGCACTGCAGAAGGCCA
TGATCGATCCTGCCAATATGCTGATGGAGATTGAAAAGGCCATACCGCGCAAGCGCGGCGGGTTTATCCTGGGGGATATC
CCGCCCTCACCACGCGGCAAGCGGGTACTGGAAGACTCGGCCGAGGAGGCCAAGCGGCTGGGACATGAGTATATCGGTAC
CGAGCACCTGCTGCTGGCATGTGCCCGCGATCAGGATGGGGAGACCCTGCGCTATCTTGCCAAGAACGGTGTGACCGCGG
ACATGCTGCGTGACATAATCGAGGAACTGTCCAACGTGGGCGGTGTGGCCTCCCAGGGGTTTGCCCAGGCCCAGAAACGC
AAGCCGACCCCCGCCGGTACCAGCGCGGCCGGTGCCAAAAAAGCCACCCCGACCCTGGATGAGTTCTCGCGCGATCTTAC
CCGGTATGCACGTGACGGCAAGCTTGATCCGGTTGTCGGCCGATCCAGAGAGATCCAGCGTGTTATTCAGATCCTGGCGC
GACGGACCAAGAACAACCCGGTCCTGATCGGTGAGCCGGGGGTAGGCAAAACCGCGATTGTGGAAGGCCTGGCCCAGCGT
ATTGTTGACGGTTCCGCTCCCGAGGTCCTGATGGACAAGCGGGTAATGACCCTGGATCTGGCCAGCCTGATCGCCGGCAC
CAAGTATCGTGGTGAGTTCGAAGAACGCCTGAAGCGGGTCATGAAGGAGATTACCACCGCCGGCAACGTTATCCTGTTTA
TCGATGAGCTGCATACCATTATCGGCGCCGGGGGTGCCGAGGGGGCCATCGATGCCTCGAACATGCTGAAGCCCGCCCTG
AGTCGCGGCGAGATTCAGGCAATCGGTGCCACCACCCTGAATGAGTACAAGAAGTACATCGAAAAGGATGCCGCTCTCGA
GCGTCGGTTCCAGATGATCTATGTCGAGGAACCCAACGTTACCGACACCGTCGAGATCCTGAAGGGTATCCAGAAACAGT
ACGAGGACCATCACAACGTCACCTATACCCCCGGTTCGATCGAGGTGGCCGCGGTGCTGAGCCATCGTTACATCGCCGAC
CGGTTTCTGCCGGACAAGGCCATCGATCTGATCGACGAAGCCGGGGCTCGCAAGCGCATCAATACCAGTGTGCGCCCGGT
CGAGCTGGCAGATCTGGAGAAAGAGATCGAACGGCTGAATCAGGAAAAGCTTACCCTGGTCAATTCCCAGAACTATGAAC
GGGCTGCCGCCGTCAGGGATGAGGTGCGCGAGCTCAAGCAGCAGATGGAGCGGATCAGGAGCGAGTGGAAGGTAGCCCTC
AAGACCGAACGCAATCTGGTGGACAGCGATGATATCCAGTATGTCATCTCGGATATCACCGGTATCCCGCTCAACCGGAT
TGCCCAGAGCGAGGGCGAAAAGCTTCTGCATATCGAGGACGAGCTGCACCGTACCGTTATTGGTCAGCACGAGGCAATCA
AGGCTATTTCTTCGGCGATCCGCCGTTCACGTATCGGACTCAGCTCGCCTGATCGACCGCTGGGCTCTTTCATCTTTCTG
GGGCCGACCGGGGTCGGGAAAACCCTGCTGGCCAAGACACTGGCGGAGTTTATGTTCGGGAACGCTGATTCCCTGATCCG
GCTGGACATGAGCGATTTTATGGAAAAGCATAATGTCAGCCGTCTGGTTGGTGCCCCTCCGGGATATGTCGGGTACGAGG
AAGGCGGACTGCTTACCGAGAAGATCCGACGCAAGCCATACAGCGTGGTGCTGCTGGATGAGATCGAGAAAGCACACCCG
GATGTGTTCAACCTGCTGCTGCAGGTTCTGGAGGAAGGCCAGCTGCAGGATAACCTTGGTCACACGGTCTCGTTCCGCAA
CACCATCCTGATCATGACCAGTAACGCCGGGGCCCGGGAGATCACCCGTGAATCGGCTGTTGGTTTCCAGACCGCCGGCA
AGTATCTGGATTACCAGGAGATCAAATCCTCGGCTATGAACGAGCTGCGCCGGGTGTTCCGCCCAGAGTTTATCAATCGT
GCAGACGAGATTGTGGTGTTCAACAGCCTGCAGGAAGAAGAGCTGCAGCGGATTGTGGACATCCTGTTGGGCGAGGTTCA
ACTGCGCCTCAGCGACAAGGAAATCGGACTGGAGATATCGGCAAATGCCCGCAAATACCTGATCGAGAACGGCTATGACC
CTAAATACGGGGCGAGACCGCTGCGACGACTGATCCAGCGCGAGATTGAGGATCCCCTGGCGGTGGACATCCTGAGCGGC
CGGTTTGGTGCCGGCAGTCATATCCAGATTGCGGTACGCAAGGATAAACTGAACTTCCGTGAGCTGGGTTCACCGGAGCC
GGAGCCCAAGCCTGAAAAAGTGGTCAGCGAGCTCTGA

Protein sequence :
MFKGLTQRAQKVLTILAQDEAKRFHADQLLPEHIMTALLKEGGGLGYKALQKAMIDPANMLMEIEKAIPRKRGGFILGDI
PPSPRGKRVLEDSAEEAKRLGHEYIGTEHLLLACARDQDGETLRYLAKNGVTADMLRDIIEELSNVGGVASQGFAQAQKR
KPTPAGTSAAGAKKATPTLDEFSRDLTRYARDGKLDPVVGRSREIQRVIQILARRTKNNPVLIGEPGVGKTAIVEGLAQR
IVDGSAPEVLMDKRVMTLDLASLIAGTKYRGEFEERLKRVMKEITTAGNVILFIDELHTIIGAGGAEGAIDASNMLKPAL
SRGEIQAIGATTLNEYKKYIEKDAALERRFQMIYVEEPNVTDTVEILKGIQKQYEDHHNVTYTPGSIEVAAVLSHRYIAD
RFLPDKAIDLIDEAGARKRINTSVRPVELADLEKEIERLNQEKLTLVNSQNYERAAAVRDEVRELKQQMERIRSEWKVAL
KTERNLVDSDDIQYVISDITGIPLNRIAQSEGEKLLHIEDELHRTVIGQHEAIKAISSAIRRSRIGLSSPDRPLGSFIFL
GPTGVGKTLLAKTLAEFMFGNADSLIRLDMSDFMEKHNVSRLVGAPPGYVGYEEGGLLTEKIRRKPYSVVLLDEIEKAHP
DVFNLLLQVLEEGQLQDNLGHTVSFRNTILIMTSNAGAREITRESAVGFQTAGKYLDYQEIKSSAMNELRRVFRPEFINR
ADEIVVFNSLQEEELQRIVDILLGEVQLRLSDKEIGLEISANARKYLIENGYDPKYGARPLRRLIQREIEDPLAVDILSG
RFGAGSHIQIAVRKDKLNFRELGSPEPEPKPEKVVSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spiaf_1064 YP_005474858.1 chaperone ATPase VFG0079 Protein 0.0 53
Spiaf_1064 YP_005474858.1 chaperone ATPase VFG0080 Protein 1e-147 52
Spiaf_1064 YP_005474858.1 chaperone ATPase VFG2084 Protein 2e-80 41