Gene Information

Name : Ferpe_0492 (Ferpe_0492)
Accession : YP_005470749.1
Strain : Fervidobacterium pennivorans DSM 9078
Genome accession: NC_017095
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.15
Position : 526865 - 528208 bp
Length : 1344 bp
Strand : +
Note : PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain

DNA sequence :
ATGACCAATAAAAACGTTAATTTTAAGAAGTGTAATTCATTTAAGTTGATGGAACTATTCGAGGAAAAGGTTAAAGAAAT
AAATCCATATGAATACATCGGAGAGGTCCAAAAAGTCATAGGCCTTACAATAGAATCGAAAGGTCCAGATGCAGCCTACG
GAGAACTTTGTAAAATCATAGTAGGCAATAAAAAGGCGCTTGCTGAAGTCGTCGGATTTAAAGAAGATATGACAGTATTA
ATGCCATTAGAAGACATAACAGGTTTGAAAAAAGGTTGTGAGGTCATAAAAACTAACAAGACCGTAAGCATACCTGTTGG
TGAAGAATTGCGTGGAAGGGTTGTTGATGCACTTGGAAGACCTATAGATGGAAAAAGACTTGTACTTAGAGAGTATCGTC
CCATTATAAACGAAGCCCCAAACCCACTTATTCGAAAAAGGATTTTAGAACCACTTCCGGTTGGTGTTCGTGCTATCGAT
GGCTTTATCACACTTGGAAAAGGACAAAGGATAGGTATCTTCGCTGGTAGTGGTGTTGGTAAGAGTACACTTCTTGGAAT
GATTGCAAGGAATACAATGGCTGACATAAACGTAATAGCGTTGATAGGAGAGCGTGGAAGGGAAGTTAGAGAATTTATTG
AGAAAGACTTGGGAGAAGAAGGTCTAAAACGTTCCGTTGTTGTAGTCTCAACATCAGACCAGCCTGCTTTGTTGAGAATC
AAAGCCTTACTTACGGCAACGACTATAGCAGAGTATTTCCGAGATAAAGGCTATGCTGTTATGTTAATGGTTGACTCGTT
AACAAGATGGGCGATGGCTCAACGTGAGGTTGGACTTGCTATTGGCGAACCACCTACAACACGAGGTTATCCCCCAAGCG
TTTTTGCACAACTTCCTAAAATCCTCGAACGTGCTGGTAACTCTGACAAGGGTAGTATAACTGGTATCTACACGGTTCTT
GTTGAAGCTGATGATTTCAACGAGCCTATTTCCGATACTGTTCGTGGTATCGTTGACGGGCATATAATACTCTCTCGTCG
CCTTGCTGAATCAAACCATTATCCGGCGATAGATGTACTCATGAGTGTTAGTCGTTTAATGACAGACATTGTAAAACCAG
AACATCTTCATGCAGCACGCTTGCTAAGAGATATAATGGCCACATACAATGACGCAAAAGACCTTATAGATGTTGGAGCA
TACAAAAAGGGAACAAATCCCAAGATAGATAAGGCTATAGAACTCATTGACGAAATCAACAAGTTTCTTAGACAAGGTAT
TCATGAAAAGATGACGTTTGAAGATACTGTTGAGTATTTATTGTCCATCGCTAGAAAACTTTGA

Protein sequence :
MTNKNVNFKKCNSFKLMELFEEKVKEINPYEYIGEVQKVIGLTIESKGPDAAYGELCKIIVGNKKALAEVVGFKEDMTVL
MPLEDITGLKKGCEVIKTNKTVSIPVGEELRGRVVDALGRPIDGKRLVLREYRPIINEAPNPLIRKRILEPLPVGVRAID
GFITLGKGQRIGIFAGSGVGKSTLLGMIARNTMADINVIALIGERGREVREFIEKDLGEEGLKRSVVVVSTSDQPALLRI
KALLTATTIAEYFRDKGYAVMLMVDSLTRWAMAQREVGLAIGEPPTTRGYPPSVFAQLPKILERAGNSDKGSITGIYTVL
VEADDFNEPISDTVRGIVDGHIILSRRLAESNHYPAIDVLMSVSRLMTDIVKPEHLHAARLLRDIMATYNDAKDLIDVGA
YKKGTNPKIDKAIELIDEINKFLRQGIHEKMTFEDTVEYLLSIARKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-100 54
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 8e-98 52
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 8e-98 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-98 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-97 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-97 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-97 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-97 52
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-89 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-87 51
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-94 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-94 50
unnamed AAL06369.1 EscN Virulence LEE Protein 7e-87 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 6e-86 50
escN AAC38383.1 EscN Virulence LEE Protein 3e-86 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 6e-86 50
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-86 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-86 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-86 50
escN AAK26715.1 EscN Virulence LEE Protein 5e-87 50
escN AAL57542.1 EscN Virulence LEE Protein 5e-87 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-87 50
escN AAC31513.1 L0034 Virulence LEE Protein 4e-86 50
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-86 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-87 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-86 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-86 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-87 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-87 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-82 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-82 50
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-79 47
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-78 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-83 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-78 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-79 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-74 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 6e-84 45
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-71 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-79 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-78 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-78 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-67 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-67 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-67 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-67 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-73 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-73 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-65 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 5e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 8e-100 54
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 1e-99 52
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 8e-95 52
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 7e-97 52
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 5e-94 51
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 2e-86 50
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 2e-86 50
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 7e-88 50
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 2e-90 49
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 1e-86 49
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 6e-68 43
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 3e-74 43
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 2e-68 43
Ferpe_0492 YP_005470749.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 5e-67 42