Gene Information

Name : ldhA (MARHY3799)
Accession : YP_005431676.1
Strain : Marinobacter hydrocarbonoclasticus ATCC 49840
Genome accession: NC_017067
Putative virulence/resistance : Resistance
Product : fermentative D-lactate dehydrogenase, NAD-dependent
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.28
Position : 3925522 - 3926532 bp
Length : 1011 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9025293; Product type e : enzyme

DNA sequence :
ATGAAAGTGGCGGTTTTCAGCACCAAGCCCTACGACGAACAGTTCCTGGCACAGGCGAACCAGGCCAGCCACCAGCATGA
ACTGGTCTTCCTGGAACCACGCCTGAATGCGGCCACTGCGGCACTGGCCAAAGGCTTCGACGCGGTATGCGTGTTCGTGA
ACGACCAGGTGGACGCCAACGTTCTGGAACAGCTGGCCGCCGGCGGCACCCGGGCCGTGGCCCTGCGCTGCGCCGGCTTC
AACAACGTCGACCTGAAAGCTGCCGAACGCCTGGGCATCGCCGTGGTGCGGGTACCGGCGTATTCCCCCTACGCGGTGGC
CGAACACACCGCCGCCCTGGTCCTGACCCTGAACCGGCAGATCCACCGGGCCTACCACCGCATTCGTGATGGCAACTTTG
CGCTCGACGGCCTGCTGGGGTTCGATCTGCGGGGTCGCACCGTGGGTGTGGTGGGTACCGGCCAGATTGGCGTGGAAGTG
GTGCGCATCATGCGCGGGTTCGGCTGCCGCGTGCTGTGTTTCGACCTGCACGCCAACCCGGAGGCGCAAACGCTGGGCGC
GGAATATGTGAGCCTGGACGAACTGTTCCGGGAAGCAGACATTGTGACCCTGCATTGCCCGCTCACCCCGGACACCCATC
ACCTGATTGATGCCGCGGCCGTGGCCAAAATGAAAAAAGGCGTGATGCTGATCAACACCAGCCGGGGCGCCATGGTGGAC
ACCGCCGCCATCATCGAAGGCCTGAAATCCGGCCAGGTGGGCTACCTGGGGCTGGATGTATATGAGGAAGAAAGCGACCT
GTTCTTCGAAGATCTCTCCAATATCGTGCTGAAAGACGACGTGTTCGCCCGTTTGCTCACATTCCCGAATGTGGTCATCA
CCGGCCACCAGGCGTTTTTCACCCGCAACGCCCTGGAAAGCATTGCCCACACAACACTCAGCAACCTGACGGACCTGGAA
ACCGGCGGCGAGTGCGCCAACCGGGTGCTGGCCGCCAACGGCAGCACCTGA

Protein sequence :
MKVAVFSTKPYDEQFLAQANQASHQHELVFLEPRLNAATAALAKGFDAVCVFVNDQVDANVLEQLAAGGTRAVALRCAGF
NNVDLKAAERLGIAVVRVPAYSPYAVAEHTAALVLTLNRQIHRAYHRIRDGNFALDGLLGFDLRGRTVGVVGTGQIGVEV
VRIMRGFGCRVLCFDLHANPEAQTLGAEYVSLDELFREADIVTLHCPLTPDTHHLIDAAAVAKMKKGVMLINTSRGAMVD
TAAIIEGLKSGQVGYLGLDVYEEESDLFFEDLSNIVLKDDVFARLLTFPNVVITGHQAFFTRNALESIAHTTLSNLTDLE
TGGECANRVLAANGST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 2e-29 42
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 4e-30 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ldhA YP_005431676.1 fermentative D-lactate dehydrogenase, NAD-dependent AF310956.2.orf4.gene Protein 2e-30 42
ldhA YP_005431676.1 fermentative D-lactate dehydrogenase, NAD-dependent U35369.1.gene5.p01 Protein 7e-30 42