Gene Information

Name : HPELS_03850 (HPELS_03850)
Accession : YP_005424890.1
Strain : Helicobacter pylori ELS37
Genome accession: NC_017063
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein (cag26)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 782038 - 785583 bp
Length : 3546 bp
Strand : -
Note : COG0419 ATPase involved in DNA repair

DNA sequence : 
ATGACTAACGAAACCATTAACCAACAACCACAAACCGAAGCGGCTTTTAACCCGCAGCAATTTATTAATAATCTTCAAGT
AGCTTTTCTTAAGCTTGATAACGCTGTCGCTTCATTTGATCCTGATCAAAAACCAATCGTTGATAAGAACGATAGGGATA
ACAGGCAAGCTTTTGATGGAATCTCGCAATTAAGGGAAGAATACTCCAATAAAGCGATCAAAAATCCTACCAAAAAGAAT
CAGTATTTTTCAGACTTTATCAATAAGAGCAACGATCTAATCAACAAAGACAATCTCATTGATGTAGAATCTTCCACAAA
GAGCTTTCAGAAATTTGGGGATCAGCGTTACCGAATTTTCACAAGTTGGGTGTCCCATCAAAACGATCCGTCTAAAATCA
ACACCCGATCGATCCGAAATTTTATGGAACATACCATACAACCCCCTATCTCTGATGATAAAGAAAAAGCAGAGTTTTTA
AAATCTGCCAAACAATCTTTTGCAGGAATCATTATAGGGAATCAAATCCGAACGGATCAAAAGTTCATGGGCGTGTTTGA
TGAATCCTTGAAAGAAAGGCAAGAAGCAGAAAAAAATGGAGAGCCTACTGGTGGGGATTGGTTGGATATTTTTTTATCAT
TTATATTTGACAAAAAACGATCTTCTGATGTCAAAGAAGCAATCAATCAAGAACCAGTTCCCCATGTCCAACCAGATATA
GCCACTACCACCACCCACATACAAGGTTTACCGCCTGAATCTAGGGATTTGCTTGATGAAAGGGGTAATTTTTCTAAATT
CACTCTTGGCGATATGGAAATGTTAGATGTTGAGGGAGTCGCTGACATTGATCCCAATTACAAGTTCAATCAATTATTGA
TTCACAATAACGCTCTGTCTTCTGTGTTAATGGGGAGTCATAATGGCATAGAACCTGAAAAAGTTTCATTATTGTATGCG
GGCAATGGTGGTTTTGGAGCCAAGCACGATTGGAACGCCACCGTTGGTTATAAAGACCAACAAGGTAACAATGTGGCTAC
AATAATTAATGTGCATATGAAAAACGGCAGTGGCTTAGTCATAGCAGGTGGTGAGAAAGGGATTAACAACCCTAGTTTTT
ATCTCTACAAAGAAGACCAACTCACAGGCTCACAACGAGCATTGAGTCAAGAAGAGATCCTAAACAAAGTAGATTTCATG
GAATTTCTTGCACAAAACAATGCTAAATTAGACAACTTGAGCGAGAAAGAGAAAGAAAAATTCCGAAATGAGATTAAGGA
TTTTCAAAAAGACTCTAAGGCTTATTTAGACGCCCTAGGGAATGATCGTATTGCTTTTGTTTCTAAAAAAGACACAAAAC
ATTCAGCTTTAATTACTGAGTTTGGTAAGGGGGATTTGAGCTACACTCTCAAAGATTATGGGAAAAAAGCAGATAAAGCT
TTAGATAGGGAGAAAAATGTTACTCTTCAAGGTAACCTAAAACATGATGGCGTGATGTTTGTTGATTATTCTAATTTCAA
ATACACCAACGCCTCCAAGAATCCCAATAAGGGTGTGGGTGCTACGAATGGCGTTTCCCATTTAGACGCAGGCTTTAACA
AGGTAGCTGTCTTTAATTTGCCTGATTTAAATAATCTCGCTATCACTAGTTTCGTAAGGCGGAATTTAGAGGATAAACTA
ACCACTAAAGGATTGTCCCTACAAGAAGCTAATAAGCTTATCAAAGATTTTTTGAGCAGCAACAAAGAATTGGTTGGAAA
GGCTTTAAACTTCAATAAAGCTGTAGCTGAAGCTAAAAGCACAGGCAACTATGATGAAGTGAAAAAAGCTCAGAAAGATC
TTGAAAAATCTCTAAGGAAACGAGAGCATTTGGAGAAAGAAGTAGAGAAAAAATTGGAGAGCAAAAGCGGCAACAAAAAT
AAAATGGAAGCGAAATCTCAAGCTAACAGCCAAAAAGATGAGATTTTTGCGTTGATCAATAAAGAGGCTAATAGGGATGC
AAGAGCAATCGCTTACAGTCAAAATCTTAAAGGCATCAAAAGGGAATTGTCTGATAAACTTGAAAATATCAACAAGGATT
TGAAAGACTTTAGTAAATCTTTTGATGAATTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGCAGAAGAAACACTAAAA
GCCCTTAAAGGCTCGGTGAAAGATTTAGGTATCAATCCGGAATGGATTTCAAAAGTTGAAAATCTTAATGCAGCTTTGAA
TGACTTCAAAAATGGCAAAAATAAGGATTTCAGCAAGGTAACGCAAGCAAAAAGCGACCTTGAAAATTCCGTTAAAGATG
TGATCATCAATCAAAAGATAACGGATAAAGTTGATGATCTCAATCAAGCGGTATCAGTGGCTAAAGCAACGGGTGATTTC
AGTAGGGTAGAGCAAGCGTTAGCCGATCTCAAAAACTTCTCAAAGGAGCAATTGGCTCAACAAGCTCAAAAAAATGAAAG
TTTCAATGTTGGAAAAAAATCTGAAATATATCAATCCGTTAAGAGTGGTGTAAACGGAACCCTAGTCGGTAATGGATTAT
CTGGAATAGAGGCCACAGCTCTCGCCAAAAATTTTTCGGATATCAAGAAAGAATTGAATGAGAAATTTAAAAATTTCAAT
AACAATAATAATGGTCTCAAAAACAGCACAGAACCCATTTATGCTAAAGTTAATAAAAAGAAAACAGGACAAGTAGCTAG
CCCTGAAGAACCCATTTATACTCAAGTTGCTAAAAAGGTAAATGCAAAAATTGACCGACTCAATCAAATAGCAAGTGGTT
TGGGTGGTGTAGGGCAAGCAGCGGGCTTCCCTTTGAAAAAGCATGATAAAGTTGATGATCTTAGTAAGGTAGGGCGATCA
GTTAGCCCTGAACCTATTTATGCTACAATTGATGATCTCGGCGGACCTTTCCCTTTGAAAAAGCATGCTAAAGTTGATGA
TCTCAGTAAGGTAGGGCTTTCAAGGAACCAAGAATTGGCTCAGAAAATTGACAATCTCAATCAAGCGGTATTAGAAGCTA
AAGCAGGTTTCTTTGGCAATCTAGAGCGAACGGTAGACAAGCTCAAAGATTCTACAAAACACAATCCCATGAATCTATGG
GCTGAAAGTGCAAAAAAAGTGCCTGCTAGTTTGTCAGCGAAACTAGACAATTACGCTACTAACAGCCACACACGCATTAA
TAGCAATATCCAAAATGGAGCAATCAATGAAAAAGCGACCGGCATGCTAACGCAAAAAAACCCTGAGTGGCTCAAGCTCG
TGAATGATAAGATAGTTGCACATAATGTGGGAAGCGTTCCTTTGTCAGAGTATGATAAAATTGGCTTCAACCAGAAGAAT
ATGAAAGATTATTCTGATTCGTTCAAGTTTTCCACCAAGTTGAACAATGCTGTAAAAGACGTTAAGTCTGGCTTTACGCA
ATTTTTATCCAATGCATTTTCTACAGGATATTACTGCTTGGCGAGGGAAAATGCGGAGCATGGAATCAAGAACGTTAATA
CAAAAGGTGGTTTCCAAAAATCTTAA

Protein sequence : 
MTNETINQQPQTEAAFNPQQFINNLQVAFLKLDNAVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKN
QYFSDFINKSNDLINKDNLIDVESSTKSFQKFGDQRYRIFTSWVSHQNDPSKINTRSIRNFMEHTIQPPISDDKEKAEFL
KSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGEPTGGDWLDIFLSFIFDKKRSSDVKEAINQEPVPHVQPDI
ATTTTHIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYA
GNGGFGAKHDWNATVGYKDQQGNNVATIINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEILNKVDFM
EFLAQNNAKLDNLSEKEKEKFRNEIKDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFGKGDLSYTLKDYGKKADKA
LDREKNVTLQGNLKHDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLDAGFNKVAVFNLPDLNNLAITSFVRRNLEDKL
TTKGLSLQEANKLIKDFLSSNKELVGKALNFNKAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKN
KMEAKSQANSQKDEIFALINKEANRDARAIAYSQNLKGIKRELSDKLENINKDLKDFSKSFDEFKNGKNKDFSKAEETLK
ALKGSVKDLGINPEWISKVENLNAALNDFKNGKNKDFSKVTQAKSDLENSVKDVIINQKITDKVDDLNQAVSVAKATGDF
SRVEQALADLKNFSKEQLAQQAQKNESFNVGKKSEIYQSVKSGVNGTLVGNGLSGIEATALAKNFSDIKKELNEKFKNFN
NNNNGLKNSTEPIYAKVNKKKTGQVASPEEPIYTQVAKKVNAKIDRLNQIASGLGGVGQAAGFPLKKHDKVDDLSKVGRS
VSPEPIYATIDDLGGPFPLKKHAKVDDLSKVGLSRNQELAQKIDNLNQAVLEAKAGFFGNLERTVDKLKDSTKHNPMNLW
AESAKKVPASLSAKLDNYATNSHTRINSNIQNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKN
MKDYSDSFKFSTKLNNAVKDVKSGFTQFLSNAFSTGYYCLARENAEHGIKNVNTKGGFQKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cagA AAR03970.1 CagA Virulence cag PAI Protein 0.0 95
HP0547 NP_207343.1 cag pathogenicity island protein (cag26) Virulence cag PAI Protein 0.0 94
cagA BAD51747.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 94
cagA AAF17598.1 CagA Virulence cag PAI Protein 0.0 94
HP0547 BAD14045.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 93
cagA BAC10428.1 CagA Virulence cag PAI Protein 0.0 92
HP0547 BAD13908.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 92
cagA AAR03881.1 CagA Virulence cag PAI Protein 0.0 92
cagA AAC44706.1 CagA Virulence cag PAI Protein 0.0 91
cagA AAR03909.1 CagA Virulence cag PAI Protein 0.0 90
cagA AGC69806.1 cag pathogenicity island protein A Virulence cag PAI Protein 0.0 86
cagA YP_003728762.1 cytotoxin-associated protein A Virulence cag PAI Protein 0.0 86
cagA AAR03939.1 CagA Virulence cag PAI Protein 0.0 86
cagA BAD51758.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 85
cagA BAC10432.1 CagA Virulence cag PAI Protein 0.0 85
HP0547 BAD13990.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 85
cagA NP_223213.1 cag island protein, cytotoxicity associated immunodominant antigen Virulence cag PAI Protein 0.0 84
cagA BAD51751.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51756.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51750.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51760.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAD51761.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 84
cagA BAC10429.1 CagA Virulence cag PAI Protein 0.0 84
HP0547 BAD13935.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 84
cagA BAD51752.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAD51766.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAD51753.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 83
cagA BAD51759.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 82
cagA BAD51764.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 82
cagA BAD51754.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
cagA BAC10426.1 CagA Virulence cag PAI Protein 0.0 78
cagA BAC10433.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 BAD14018.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA YP_005777288.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
HP0547 BAD14072.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAD51755.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
cagA BAC10421.1 CagA Virulence cag PAI Protein 0.0 78
cagA YP_005779046.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
HP0547 BAD13799.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAD51749.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
cagA BAC10431.1 CagA Virulence cag PAI Protein 0.0 78
cagA BAC10435.1 CagA Virulence cag PAI Protein 0.0 78
HP0547 BAD13963.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA BAD51762.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 78
HP0547 BAD13880.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA YP_005775747.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 78
cagA AAF17597.1 CagA Virulence cag PAI Protein 0.0 78
cagA BAD51744.1 cytotoxin associated protein A Virulence cag PAI Protein 0.0 77
cagA BAC10420.1 CagA Virulence cag PAI Protein 0.0 77
cagA BAC10419.1 CagA Virulence cag PAI Protein 0.0 77
cagA YP_005774524.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 76
HP0547 BAD13853.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 75
cagA BAC10427.1 CagA Virulence cag PAI Protein 0.0 74
cagA BAC10430.1 CagA Virulence cag PAI Protein 0.0 69
cagA BAC10423.1 CagA Virulence cag PAI Protein 0.0 69
cagA BAC10422.1 CagA Virulence cag PAI Protein 0.0 68
HP0547 BAD13826.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 68
cagA BAC10424.1 CagA Virulence cag PAI Protein 0.0 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPELS_03850 YP_005424890.1 cag pathogenicity island protein (cag26) VFG0306 Protein 0.0 94