Gene Information

Name : guaA (HPELS_01480)
Accession : YP_005424441.1
Strain : Helicobacter pylori ELS37
Genome accession: NC_017063
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 292996 - 294522 bp
Length : 1527 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATACAGA
AATAGTCCCTTTTTTTGAAAGCGTAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGCGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTATAAGCCCAATGAAAAAATCTTTGATTTGAATTTACCGATTTTAGGGATTTGCTACGGC
ATGCAGTATCTGGTGGATTTTTTTGGGGGGGTAGTGGTTGGTGCGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CGCTCAAAATTCTGTGATTTTTGAAGGCGTGAAGATTAAAAGCCTTGTGTGGATGAGCCATATGGATAAAGTCACAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGTGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTAGTTTGCGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATTGTGAAACTGAAAGAAAAAATCGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTACACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTGGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAGGGTGCAAGCAATGTTTAAAGACTTGCAAATCCCTTTAAA
CACAATAGACGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAGTTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAAAAGCACCATTTAAAAGGCAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACGCACCATAATGTGGGCGGACT
GCCTGAATGGATGGACTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTGCGCTTATTGGGTAAAGAAT
TGGGCGTTAGCCAGGATTTTTTAATGCGCCACCCCTTTCCAGGGCCTGGGCTTGCTGTAAGGATTTTAGGCGAAATCAGT
GAGAGTAAGATCAAGCGCTTGCAAGAAGCGGATTTTATTTTTATAGAGGAGCTTAAAAAAGCCCATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTGTTGAATGTCAATTCTGTGGGGGTTATGGGGGATAATCGCACCTATGAAAATGCTATTT
GTTTAAGAGCGGTAAACGCGAGCGATGGCATGACAGCGAGCTTTTCATTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGTATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYTEIVPFFESVENIQKKAPKGLILSGGPASVYAKDAYKPNEKIFDLNLPILGICYG
MQYLVDFFGGVVVGANEQEFGKAVLEIAQNSVIFEGVKIKSLVWMSHMDKVTELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREIVKLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKERVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMRHPFPGPGLAVRILGEIS
ESKIKRLQEADFIFIEELKKAHLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-132 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-132 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-115 47