Gene Information

Name : hasB (MGAS1882_1775)
Accession : YP_005412485.1
Strain : Streptococcus pyogenes MGAS1882
Genome accession: NC_017053
Putative virulence/resistance : Virulence
Product : UDP-glucose dehydrogenase protein HasB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1762291 - 1763499 bp
Length : 1209 bp
Strand : +
Note : CDD hit: non-specific, cl353 = UDP-glucose/GDP-mannose dehydrogenase family, central domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol

DNA sequence :
ATGAAAATAGCAGTTGCTGGATCAGGATATGTTGGATTATCACTAGGAGTTCTTTTATCACTTCAAAACGAAGTCACTAT
TGTTGATATTCTTCCCTCTAAAGTTGATAAGATTAATAATGGCTTATCACCAATTCAAGATGAATATATTGAAGATTACT
TAAAAAGTAAGCAATTATCTATTAAAGCAACTTTAGATAGCAAAGCAGCTTATAAAGAAGCGGAACTGGTCATTATTGCC
ACACCTACAAATTACAACAGTAGAATTAATTATTTTGATACACAGCATGTTGAAACAGTTATCAAAGAGGTACTAAGCGT
TAATAGCCATGCAACTCTTATCATCAAATCAACAATTCCAATAGGTTTCATTACTGAAATGAGACAGAAATTCCAAACTG
ATCGTATTATCTTCAGCCCTGAATTTTTAAGAGAATCTAAAGCTTTATATGACAACTTATATCCAAGCCGAATTATTGTT
TCTTTTGAAGAAAACGATTCTCCAAAAGTAAAGGCAGACGCAGAAAAATTTGCACTTTTATTAAAGTCTGCAGCTAAAAA
AAATAATGTACCAGTACTTATTATGGGAGCTTCAGAAGCTGAAGCAGTAAAACTATTTGCCAATACTTATTTAGCGTTAA
GGGTAGCTTATTTTAATGAGTTAGACACTTACGCAGAATCGAGAAAATTAAATAGTCACATGGTTATTCAAGGAATTTCT
TATGATGATCGAATAGGAATGCATTATAATAACCCATCATTTGGTTATGGAGGTTATTGTCTACCTAAAGATACGAAGCA
ATTATTGGCAAATTACAATAATATTCCCCAAACGCTAATTGAAGCTATCGTTTCATCAAATAATGTGCGCAAGTCCTATA
TTGCTAAGCAAATTATCAACGTCTTAGAAGAGCAGGAGTCCCCAGTAAAAGTAGTCGGGGTTTACCGTTTAATTATGAAA
AGTAACTCAGATAATTTTAGAGAAAGTGCTATCAAAGATGTTATTGACATTCTTAAAAGTAAAGACATTAAGATAATTAT
TTATGAGCCAATGTTAAACAAACTTGAATCTGAAGATCAATCTGTACTTGTAAATGATTTAGAGAATTTCAAGAAACAAG
CAAATATTATCGTAACTAATCGCTATGATAATGAATTACAAGATGTTAAAAATAAAGTTTACAGTAGAGATATTTTTGGT
AGAGACTAG

Protein sequence :
MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEDYLKSKQLSIKATLDSKAAYKEAELVIIA
TPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
SFEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMVIQGIS
YDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLEEQESPVKVVGVYRLIMK
SNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFG
RD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 2e-70 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasB YP_005412485.1 UDP-glucose dehydrogenase protein HasB VFG0963 Protein 6e-155 99