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Name : slo (MGAS1882_0177) Accession : YP_005410946.1 Strain : Streptococcus pyogenes MGAS1882 Genome accession: NC_017053 Putative virulence/resistance : Virulence Product : streptolysin O precursor protein Slo Function : - COG functional category : - COG ID : - EC number : - Position : 151155 - 152870 bp Length : 1716 bp Strand : + Note : CDD hit: non-specific, cl315 = Thiol-activated cytolysin; Thiol-activated cytolysin.; SignalP-HMM predicted secretion signal peptide, Signal peptide probability: 1.000, Max cleavage site probability: 0.972 between pos. 31 and 32, ANA-ES DNA sequence : ATGTCTAATAAAAAAACATTTAAAAAATACAGTCGCGTCGCTGGGCTACTAACGGCAGCTCTTATCATTGGTAATCTTGT TACTGCTAATGCTGAATCGAACAAACAAAACACTGCTAGTACAGAAACCACAACGACAAATGAGCAACCAAAACCAGAAA GTAGTGAGCTAACTATCGAAAAAGCAGATCAGAAAATGGATGATATGCTTAACTCTAACGATATGATTAAGCTTGCTCCC AAAGAAATGCCACTAGAATCTGCAGAAAAAGAAGAAAAAAAGTCAGAAGACAAAAAAAAGAGCGAAGAAGATCACACTGA AGAAATCAATGACAAGATTTATTCACTAAATTATAATGAGCTTGAAGTACTTGCTAAAAATGGTGAAACCATTGAAAATT TTGTTCCTAAAGAAGGCGTTAAGAAAGCTGATAAATTTATTGTCATTGAAAGAAAGAAAAAAAATATCAACACTACACCA GTCGATATTTCCATCATTGACTCTGTCACTGATATGACCTATCCAGCAGCCCTTCAGCTGGCTGATAAAGGTTTTACCGA AAACAAACCAGACGCGGTAGTCACCAAGCGAAACCCACAAAAAATCCATATTGATTTACCAGGTATGGGAGACAAAGCAA CGGTTGAGGTCAATGACCCTACCTATGCCAATGTTTCAACAGCTATTGATAATCTTGTTAACCAATGGCATGATAATTAT TCTGGTGGTAATACGCTTCCTGCCAGAACACAATATACTGAATCAATGGTATATTCTAAATCACAGATTGAAGCAGCTCT AAATGTTAATAGCAAAATCTTAGATGGTACTTTAGGCATTGATTTCAAGTCGATTTCAAAAGGTGAAAAGAAGGTGATGA TTGCAGCATACAAGCAAATTTTTTACACCGTATCAGCAAACCTTCCTAATAATCCTGCGGATGTGTTTGATAAATCAGTG ACCTTTAAAGATTTGCAACGAAAAGGTGTCAGCAATGAAGCTCCGCCACTCTTTGTGAGTAACGTAGCCTATGGTCGAAC TGTTTTTGTCAAACTAGAAACAAGTTCTAAAAGTAATGATGTTGAAGCGGCCTTTAGTGCAGCTCTAAAAGGAACAGATG TTAAAACGAATGGAAAATACTCTGATATCTTAGAAAATAGCTCATTTACAGCTGTCGTTTTAGGAGGAGATGCTGCAGAG CACAATAAGGTAGTCACAAAAGACTTTGATGTTATTAGAAACGTTATCAAAGACAATGCTACCTTCAGTAGAAAAAACCC AGCTTATCCTATTTCATACACCAGTGTTTTCCTTAAAAATAATAAAATTGCGGGTGTCAATAATAGAACTGAATACGTTG AAACAACATCTACCGAGTACACTAGTGGAAAAATTAACCTGTCTCATCGAGGCGCGTATGTTGCTCAATATGAAATCCTT TGGGATGAAATCAATTATGATGACAAAGGAAAAGAAGTGATTACAAAACGACGTTGGGACAACAACTGGTATAGTAAGAC ATCACCATTTAGCACAGTTATCCCACTAGGAGCTAATTCACGAAATATCCGTATCATGGCTAGAGAGTGCACCGGCTTAG CTTGGGAATGGTGGCGAAAAGTGATCGACGAAAGAGATGTGAAACTGTCTAAAGAAATTAATGTCAACATCTCAGGATCA ACCCTGAGCCCATATGGTTCAATTACTTATAAATAG Protein sequence : MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTIEKADQKMDDMLNSNDMIKLAP KEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP VDISIIDSVTDMTYPAALQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWHDNY SGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSV TFKDLQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAE HNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHRGAYVAQYEIL WDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGS TLSPYGSITYK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| slo | YP_281505.1 | streptolysin O | Virulence | Not named | Protein | 0.0 | 99 |
| hly | AAA69525.1 | listeriolysin O | Virulence | LIPI-1 | Protein | 1e-93 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| slo | YP_005410946.1 | streptolysin O precursor protein Slo | VFG0976 | Protein | 0.0 | 99 |
| slo | YP_005410946.1 | streptolysin O precursor protein Slo | VFG2275 | Protein | 2e-149 | 67 |
| slo | YP_005410946.1 | streptolysin O precursor protein Slo | VFG1363 | Protein | 6e-91 | 43 |
| slo | YP_005410946.1 | streptolysin O precursor protein Slo | VFG0074 | Protein | 1e-93 | 42 |
