Gene Information

Name : irr (MGAS1882_1628)
Accession : YP_005412339.1
Strain : Streptococcus pyogenes MGAS1882
Genome accession: NC_017053
Putative virulence/resistance : Resistance
Product : TCS signal tranduction response regulator Irr
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1615547 - 1616200 bp
Length : 654 bp
Strand : -
Note : CDD hit: specific, cl9944 = Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two

DNA sequence :
ATGTTTAAAATATTAGTAGTTGAAGATGATGATACCATCAGTCAAGTGATTTGTGAGTTTTTAAAAGCGAATAACTATGA
TCCAGATTGTGTATTTGATGGCCAAGCTGCCTTAGACAAGTGGCAGACAACGTCTTATGATCTGATTATTTTAGACATCA
TGCTCCCTTCCTTAAGTGGCTTAGAAGTGCTAAAAACAATTCGAAAGACATCAGATGTCCCTATTATTATGCTAACGGCA
TTAGATGACGAGTACACACAGCTTGTAAGCTTCAACCATTTGATTAGTGATTATGTGACCAAACCATTTTCACCACTCAT
TTTAATCAAACGTATCGAAAATGTATTACGCGTCTCTACTCCAGATGAAAAGCGCCAAATCGGAGACTTACTTGTTGATG
AGACCGAACATAGCGTCTATTGGCAAGGAACATTGGTCAAACTAACCAAAAAAGAATATGACATTATTGATTATTTAGCA
AAACGTCACCAAAAGATTGTCACCAGAGACCAATTGATGGATGACATATGGGGCTATTCTGAACTGGACACGCGTGTCCT
TGACAATCACATCAAGAACCTTCGTAAAAAAATGACGGGTATTCCCCTCAAGACAATTACAGGCATGGGCTATTTATTGG
GAGAGCGTGAGTGA

Protein sequence :
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTA
LDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-34 41
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 6e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irr YP_005412339.1 TCS signal tranduction response regulator Irr AF310956.2.orf0.gene Protein 9e-35 41
irr YP_005412339.1 TCS signal tranduction response regulator Irr AE016830.1.gene2255. Protein 2e-34 41
irr YP_005412339.1 TCS signal tranduction response regulator Irr U35369.1.gene1.p01 Protein 2e-34 41