Gene Information

Name : dexB (MGAS1882_1587)
Accession : YP_005412300.1
Strain : Streptococcus pyogenes MGAS1882
Genome accession: NC_017053
Putative virulence/resistance : Unknown
Product : glucan 1,6-alpha-glucosidase protein DexB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1565858 - 1567471 bp
Length : 1614 bp
Strand : -
Note : CDD hit: non-specific, cl7893 = Alpha amylase, catalytic domain; Alpha amylase is classified as family 13 of the glycosyl hydrolases. The structure is an 8 stranded alpha/beta barrel containing the active site, interrupted by a 7 a.a. calcium-binding doma

DNA sequence :
ATGAAGAAACACTGGTGGCATAAAGCTACGATTTATCAGATTTACCCGAGATCCTTTAAAGACACCAGCGGCAATGGTAT
TGGTGATTTAAAAGGCATTACCAGTCAACTGGACTACTTGCAAAAACTTGGCATTACAGCCATTTGGTTATCTCCTGTTT
ACCAAAGTCCAATGGATGACAATGGTTATGACATCTCTGACTATGAAGCGATTGCTGATGTTTTTGGAGACATGGCAGAT
ATGGATGAGCTCTTAGCAGCAGCTAATGAGCGAGGCATTAAGATTATCATGGACTTGGTGGTCAACCATACGTCTGATGA
GCATGCTTGGTTTGTTGAAGCTAGGGAAAACCCTAATAGTCCTGAGCGTGATTTTTATATTTGGCGAGATGAACCTAACG
ATTTGACTTCTATTTTTAGTGGCTCAGCTTGGGAATATGATAATGCATCAGGCCAATATTATTTGCACCTTTTTAGCAAA
CGTCAGCCAGATCTCAACTGGGAGAATGAAGCTTTACGTCATAAAATTTACGATATGATGAATTTCTGGATTGCAAGGGG
CATCGGTGGTTTTCGTATGGACGTGATTGACCTGATTGGGAAGGTTCCAGATTCTGAAATCACGGGTAACGGGCCGCGCT
TACACGATTACCTCAAAGAAATGAATCAAGCAACCTTTGGCAATCATGACGTGATGACTGTCGGTGAGACTTGGGGAGCA
ACGCCTGAAATTGCTCGCCAGTATTCTCGCCCTGAAAACAAAGAGTTATCCATGGTCTTCCAATTTGAGCATGTGGGTCT
TCAACATAAACCTGACGCTCCCAAGTGGGATTATGCGGAAGAACTGGATGTTCCTGCTCTTAAAGCTATTTTCAGCAAGT
GGCAGACAGAATTAAAGTTGGGAGAAGGCTGGAATTCGCTTTTTTGGAATAACCATGACTTGCCACGGGTCTTATCCATT
TGGGGCAATGACAGCACTTACCGAGAAAAATCAGCCAAGGCTTTAGCTATTTTACTGCATTTGATGCGAGGAACCCCTTA
CATTTACCAAGGAGAAGAGATTGGCATGACCAATTATCCTTTTAGAGACTTCACCGAGGTTAATGATATTGAGTCCCTTA
ACTATGCTAAGGAAGCTATGGGAAATGGAGTGTCAGCTGCGCGTGTGATGGATAGCATCCGTAAGGTAGGACGAGACAAT
GCTAGAACGCCGATGCAGTGGTCTAAGGATACACATGCTGGCTTTTCTAAAGCCCAAGAGACTTGGTTGCCGGTCAACCC
CAACTACCAAGACATCAATGTGGCCGATGCCCTTGCTGATTCAGATTCTATTTTTTACACCTACCAAAAATTGATTGCCT
TGCGTAAGGAGCAAGACTGGCTAGTTGAAGCGGATTATCACCTCTTGCCAACAGCTGATAAAGTGTTTGCTTATCAGCGT
CAGCTTGGAGAAGAGACGTATGTGATTGTTGTCAATGTGTCTGATGAGGAGCAAGTCTTTGCCAAAGACTTAGCAGGTGC
ACAAGTGATCATCACCAATACAGATGTGGACACGGTATTAAAGACCAAGCACTTACAACCTTGGGATGCCTTTTGTCTCA
AACTGAAGGCTTAG

Protein sequence :
MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLGITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMAD
MDELLAAANERGIKIIMDLVVNHTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
RQPDLNWENEALRHKIYDMMNFWIARGIGGFRMDVIDLIGKVPDSEITGNGPRLHDYLKEMNQATFGNHDVMTVGETWGA
TPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKWDYAEELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSI
WGNDSTYREKSAKALAILLHLMRGTPYIYQGEEIGMTNYPFRDFTEVNDIESLNYAKEAMGNGVSAARVMDSIRKVGRDN
ARTPMQWSKDTHAGFSKAQETWLPVNPNYQDINVADALADSDSIFYTYQKLIALRKEQDWLVEADYHLLPTADKVFAYQR
QLGEETYVIVVNVSDEEQVFAKDLAGAQVIITNTDVDTVLKTKHLQPWDAFCLKLKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
malL YP_251987.1 oligosaccharide alpha-1,6-glucosidase Not tested SCCmec Protein 7e-117 48