Gene Information

Name : tkt (MGAS1882_1333)
Accession : YP_005412059.1
Strain : Streptococcus pyogenes MGAS1882
Genome accession: NC_017053
Putative virulence/resistance : Unknown
Product : transketolase protein Tkt
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1308865 - 1310850 bp
Length : 1986 bp
Strand : -
Note : CDD hit: specific, cl1629 = Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link b

DNA sequence :
ATGACATTTGATGCAATTGACCAGTTGGCAGTAAACACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTC
TGGACACCCAGGACTTCCAATGGGGGCAGCACCTATGGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAA
CAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCCTATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTACAC
TTAGCTGGTTATGATTTATCTGTAGAAGATTTAAAGAACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGT
GAATCACACAGACGGTGTCGAAGCAACCACAGGACCTCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAG
AAGCTCATCTAGCAGCTAAATTTAACAAACCAGGCTTTGACATCGTTGATCACTACACATTTGCTTTGAATGGTGACGGT
GACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGTATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGA
TTCAAACGACATCTCTCTTGATGGTCCAACCTCTATGGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTACGGTT
GGCAACATATCCTTGTGAAAGATGGAAATGATTTAGAAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAG
AAACCAACCATCATCGAAGTCAAAACCATTATTGGTTTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCC
TCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGCTTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAA
CAGAGCGCTTTGCTCAAGGCCTTCAAGCGCGTGGTGAAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATGAA
GCAGAATATCCAGAATTAGCAGCAGAATACCAAAAAGCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGA
ACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCAACAAGCCATCCAACAAATTTCAGAACAAGTAGCCTCTTTCTGGG
GTGGGTCAGCAGACCTTTCAGCTTCAAACAATACTATGGTTAAGGCTGAAACAGATTTCCAACCAGGTCATTATGAAGGC
CGTAACGTCTGGTTTGGCGTTCGTGAATTTGCCATGGCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGT
TTACGGTGGAACCTTCTTTGTCTTCTCAAACTATCTTCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAGCTTACCAACAG
TTTATGTCATGACACATGATTCTATCGCTGTCGGTGAGGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTT
CGTTCAATGCCTAACTTGAACGTTATTCGTCCAGCAGACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGA
AACAGATCGCCCAACCATGCTTGTATTGACGCGTCAAAATCTCCCAGTGCTTGAAGGAACAAAAGAATTGGCAGAAGATG
GTCTTAACAAAGGAGCTTACATCTTGTCAGAAGCCAAAGGCGACCTTGAAGGTATCTTGATTGCAACAGGTTCAGAAGTT
AAATTAGCTTTAGATACTCAAGATAAACTTGAGTCAGAAGGGATTCATGTTCGCGTCGTATCTATGCCATCGCAAAATAT
CTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCATCCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTT
CAAGCTTTGGCTGGGCAAAATATGTCGGCCTAGCAGGAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGA
AATCGTATCTTCGAAGAATATGGTTTCACTGTGGCAAATGCAACTGAGTTATACAAATCACTCTAG

Protein sequence :
MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLH
LAGYDLSVEDLKNFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETE
KPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYE
AEYPELAAEYQKAFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEG
RNVWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQSLPTVYVMTHDSIAVGEDGPTHEPIEQLASV
RSMPNLNVIRPADGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEV
KLALDTQDKLESEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPG
NRIFEEYGFTVANATELYKSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-127 51
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-125 49