Gene Information

Name : speK (MGAS1882_1106)
Accession : YP_005411845.1
Strain : Streptococcus pyogenes MGAS1882
Genome accession: NC_017053
Putative virulence/resistance : Virulence
Product : streptococcal pyrogenic exotoxin (K) SpeK
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1100691 - 1101470 bp
Length : 780 bp
Strand : -
Note : CDD hit: non-specific, pfam02876, Staphylococcal/Streptococcal toxin, beta-grasp domain; Staphylococcal/Streptococcal toxin, beta-grasp domain.; SignalP-HMM predicted secretion signal peptide, Signal peptide probability: 1.000, Max cleavage site probabili

DNA sequence : 
ATGAAAAAAAATACCTTGACTTTGTTATTCCTTGTGTGTGTATCGCTTGCTCTATACACTACTGAGAGTGTCTTTTCAGA
TACGTACAATACAAATGATGTTAGAAATCCAAGGAACATATATGCTCCTAGATATGATAAAGACGAAATTTTGGATAATA
GAAGATTAAAAGAAATATATAATAAAGAAATTATTGAAAAAAATAATATATCGATAAATGCCAAACAAGGAACGCAATTG
ATTTTTAATACGGATGAAAATACTACAGTTTGGAATGATAACACTTTTAAGAAAGTCATATCTAGTAATCTTTCTCCTTC
ACAGGAAAGAATGTTTAATGTTGGTGATCATGTGAATATTTTTGCTATAGTAAAGTCATATCATGTTGTATGCAAGGAAC
AATTCAATTATAGTGATGGGGGAATAATAAAAACAAGTGATGTAAAACCAGAAGAAAAAGCAATTTATATTAATATTTTT
GGTGAAAAAGAATTACGAACATTAACAGCTAAAGATAAGATTACCTTTAAAAATAATATTGTAACTCTTCAGGAGATTGA
TGTTAGACTTAGGAAAAGTTTGATGGGGGACAGCAAAATAAAATTGTATGAGTACGATTCTTTGTATAAAAAAGGGTTTT
GGGATATTCATTATAAAGACGGTGGCATTAGACACACCAATTTATTTACTTACCCCGACTATACAGATAATGAAACGATT
GATATGAGTAAAGTTAGTCACTTTGATGTTCACTTAAACGAAGATTTTTCTAAAGATTAG

Protein sequence : 
MKKNTLTLLFLVCVSLALYTTESVFSDTYNTNDVRNPRNIYAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQL
IFNTDENTTVWNDNTFKKVISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYSDGGIIKTSDVKPEEKAIYINIF
GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHYKDGGIRHTNLFTYPDYTDNETI
DMSKVSHFDVHLNEDFSKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
seeL YP_002746964.1 exotoxin L precursor Virulence ¥ÕSeq3 Protein 3e-104 98
seeM YP_002746963.1 exotoxin M precursor Virulence ¥ÕSeq3 Protein 1e-31 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
speK YP_005411845.1 streptococcal pyrogenic exotoxin (K) SpeK VFG0953 Protein 2e-107 100
speK YP_005411845.1 streptococcal pyrogenic exotoxin (K) SpeK VFG0958 Protein 2e-61 58
speK YP_005411845.1 streptococcal pyrogenic exotoxin (K) SpeK VFG0957 Protein 7e-34 42