Gene Information

Name : MC1_00370 (MC1_00370)
Accession : YP_005392317.1
Strain : Rickettsia parkeri Portsmouth
Genome accession: NC_017044
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 53148 - 55721 bp
Length : 2574 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATATTGATAAATTTACTGCACATGCTAAATCAGTGATAGCTAGTAGCCAATCACTTGCTGCTAAAAATGATCATCA
GCAAATATTACCTTTGCATTTATTATCTAGTCTTTTAAGTGAAGAAACAGGTATAATTCAAACCCTTATTAATAATACTG
GCGGTAATATAACCTTATTAAAAGATCAAGTTCAGCTAGAACTAAATAAAATCCCAAAAGTTCAGGTTGAGGGAGGGGGA
CAAGTTTATTCTTCTGCTGAAGCTCTTAAAGTTTTAGAAAAAGCTAGTAGCATTGCTAAAGACAGTGGGGATAGCTTTGT
AACCATAGAGCGTATATTTGAAGCATTAACGTATGATAATACTATAGCCGGTAAAATTTTAACGAATAATGGAATTAATA
ATAAAAAAATAGCAACAGCTATTTTACAGTTTCGTAAAGGCAAAAAAGCAGATACCGAATCGGCAGAAAATAGTTACGAT
GCTTTAAAGAAATACGGCAGAGACGTAACAGAGCTTGCCGAAAGTGGTAAGCTTGATCCGATAATCGGACGTGATGAAGA
AATAAGAAGAACGGTGCAGGTACTATCACGACGTATGAAAAATAATCCTGTATTGATTGGAGAACCTGGAGTCGGTAAAA
CTGCTATAATAGAGGGGCTTGCACAACGAATATTTAGTAAGGACGTACCTGAATCGCTTGTTAATTGCCGTATTATTGAG
CTTGATATGGGAGCTTTAATAGCGGGAGCTAAATATCGAGGCGAATTTGAAGAACGTCTTAAAGCAGTGCTTAGCGAAAT
CAAAGAATCAAGCGGTGAAATTATTTTATTTATCGATGAATTGCATCTATTAGTCGGTACGGGAAAAACCGACGGTGCTA
TGGATGCCTCGAATTTACTAAAGCCGATGCTTGCTCGTGGTGAACTGCATTGTATCGGTGCTACTACTCTAGATGAATAT
CGTAAATATATCGAGAAAGATGCGGCACTTGCTCGTCGTTTTCAGCCTGTTTACGTGAGTGAGCCGACGGTTGAGGATAC
TATATCAATACTTAGAGGAATTAAAGAAAAATATGAGCTGCATCATGCAGTGCGAATTTCCGATAGTGCAATAGTTGCAG
CAGCGACGTTATCAAACCGTTATATTACCGATCGTTATTTACCTGATAAAGCTATTGATTTGATTGATGAAGCTTGTAGC
CGTATGAAAATAGAGCTATCCAGTAAACCAGAAGAGCTTGATGAGCTGGACCGTCGTATTATTCAGATAAAAGTAGAGCT
TGCAGCACTTAAAAAAGAAAATGACGAGCATTCTAAAAAGAAAATAGAGCATTTAACTACAGCATTAGAAAAATTAGAGT
CTCAATCCTATGATATGGGAGCTAAATGGCAAGCTGAAAAGTCTAAACTACAGCAAACACAAAAGCTCAAAGAAGAACTA
GACCGTAGCCGAAACGAGCTTGAACGTGCCGAACGTGATGCTAATCTCGCTAAAGCTAGTGAGCTAAAATACGGAATTAT
ACCTGAGATTATGAAAAAGATTCAGGAAGCCGAAAGTATGGATAATAAAGGGCTGTTAAAAGAAATTGTATCGGAAAGTG
ATATAGCAAGTATTATCTCTCGTATTACTGGTATTCCAATTGATACGATGCTATCAAGTGAACGTGAGCGTTTGCTTGTG
ATGGAGCAGAAATTACGAGAATCGGTAATAGGGCAGGATAAGGCAATTAAAGGTGTTAGTGATGCGGTAAGAAGATCACG
TGCAGGGATTCAAGATATTAACCGCCCGCTTGGTTCGTTCTTATTCTTAGGACCGACCGGAGTCGGTAAAACCGAGCTTA
CCAAAGCCTTAGCTGGTTTTCTTTTTGATGACCGTAATGCAATACTTCGTATAGATATGTCGGAATATATGGAGAAGCAC
GCTATTTCTCGCCTGATAGGAGCTCCTCCCGGCTATATCGGATATGATCAAGGCGGAGTGTTGACGGAGGCAGTAAGACG
CCGTCCTTATCAGGTAATATTATTTGATGAGGTTGAAAAAGCCCATCCCGACATATTTAATATTATGCTGCAAATACTTG
ATGAGGGAAGATTAACAGATAGTCAAGGTATAACGGTTGATTTTAAGAATACTATAATAGTTTTAACGTCTAATTTAGGT
GCTGAGGTACTCGTTAATCAGAAAGAGGACGAAGATACATATAAAGTAAAGGATGAGGTTATGGAATATGTAAAAGCAGT
ATTTAAACCTGAGTTTTTAAACAGACTAGACGAGATTATATTATTCCATCGCCTAAATCGTAATAATATTCATGATATAG
TTAAGATACAGCTTGAAAGTTTAAAGAAAATTTTACTAGCACAAAATATTATTCTTGAATTTGATGAATCTGCATTAAAT
TATTTAGCCGAAAAAGGTTATGATCCAAGCTTTGGAGCAAGACCCTTAAAACGTCTTATCCAGCGGGAAATACAAAATAA
TTTAGCCAAAATGATTTTAGCAGGCGAAATAAGTAGCGGTAAAACGGTTAAAATAAATTCAAAGGATAAAGAATTGAAGG
TAACAATGAGTTGA

Protein sequence :
MNIDKFTAHAKSVIASSQSLAAKNDHQQILPLHLLSSLLSEETGIIQTLINNTGGNITLLKDQVQLELNKIPKVQVEGGG
QVYSSAEALKVLEKASSIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINNKKIATAILQFRKGKKADTESAENSYD
ALKKYGRDVTELAESGKLDPIIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLVNCRIIE
LDMGALIAGAKYRGEFEERLKAVLSEIKESSGEIILFIDELHLLVGTGKTDGAMDASNLLKPMLARGELHCIGATTLDEY
RKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYELHHAVRISDSAIVAAATLSNRYITDRYLPDKAIDLIDEACS
RMKIELSSKPEELDELDRRIIQIKVELAALKKENDEHSKKKIEHLTTALEKLESQSYDMGAKWQAEKSKLQQTQKLKEEL
DRSRNELERAERDANLAKASELKYGIIPEIMKKIQEAESMDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLV
MEQKLRESVIGQDKAIKGVSDAVRRSRAGIQDINRPLGSFLFLGPTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKH
AISRLIGAPPGYIGYDQGGVLTEAVRRRPYQVILFDEVEKAHPDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
AEVLVNQKEDEDTYKVKDEVMEYVKAVFKPEFLNRLDEIILFHRLNRNNIHDIVKIQLESLKKILLAQNIILEFDESALN
YLAEKGYDPSFGARPLKRLIQREIQNNLAKMILAGEISSGKTVKINSKDKELKVTMS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-160 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MC1_00370 YP_005392317.1 chaperone ClpB VFG0079 Protein 2e-167 47
MC1_00370 YP_005392317.1 chaperone ClpB VFG2084 Protein 4e-105 41