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Name : apbA (MGAS15252_0686) Accession : YP_005388733.1 Strain : Streptococcus pyogenes MGAS15252 Genome accession: NC_017040 Putative virulence/resistance : Unknown Product : 2-dehydropantoate 2-reductase protein ApbA Function : - COG functional category : - COG ID : - EC number : - Position : 668455 - 669378 bp Length : 924 bp Strand : + Note : CDD hit: multi-dom, TIGR745 = 2-dehydropantoate 2-reductase; This model describes enzymes that perform as 2-dehydropantoate 2-reductase, one of four enzymes required for the de novo biosynthesis of pantothenate (vitamin B5) from Asp and 2-oxoisovalerate. DNA sequence : ATGTTAGTTTATATTGCTGGCTCAGGAGCCATGGGGTGCCGTTTTGGTTACCAAATTTCAAAAACAAATAACGATGTGAT TTTGTTAGATAACTGGGAAGATCATATCAATGCCATTAAAGAAAACGGTTTAGTGGTGACAGGGGATGTGGAAGAAACAG TTAAGCTTCCTATTATGAAACCGACTGAAGCCACTCAAGAAGCCGATTTGATTATCTTGTTTACAAAAGCAATGCAGTTG CCACAAATGCTTCAAGACATTAAAGGCATTATTGGAAAAGAAACCAAAGTGCTTTGCCTTTTAAATGGTCTTGGACACGA AGACGTTATTCGTCAGTACATTCCAGAGCACAACATTTTGATGGGGGTCACTGTCTGGACTGCTGGTCTAGAAGGTCCTG GTCGTGCTCATCTTCAAGGTGTGGGAGCACTTAACTTACAAAGCATGGATCCAAGCAATCAAGAAGCTGGACACCAAGTG GCTGATTTGTTAAATGAAGCTAACTTGAATGCGACTTATGATGAGAATGTTGTGCCAAACATCTGGCGGAAAGCTTGCGT GAATGGTACCATGAACTCAACTTGTGCCCTTCTAGATTGTACAATTGGTGAATTATTTGCCAGTGAAGACGGTCTCAAAA TGGTAAAAGAAATCATCCATGAGTTTGTTATCGTTGGTCAAGCAGAAGGTGTCGAACTAAACGAAGAAGAAATCACACAA TATGTAATGGATACATCTGTTAAAGCTGCTCACCATTACCCATCAATGCACCAAGACCTTGTGCAAAATCACCGATTGAC TGAAATTGATTTTATCAATGGTGCAGTCAATACCAAAGGTGAAAAGCTTGGTATCAATACTCCATACTGCCGTATGATTA CAGAGCTAGTTCACGCTAAAGAAGCAGTGTTGAACATCCAATAA Protein sequence : MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGLVVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQL PQMLQDIKGIIGKETKVLCLLNGLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQV ADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEIIHEFVIVGQAEGVELNEEEITQ YVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAVNTKGEKLGINTPYCRMITELVHAKEAVLNIQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| EF0517 | NP_814296.1 | 2-dehydropantoate 2-reductase | Not tested | Not named | Protein | 2e-72 | 50 |
| ef0037 | AAM75243.1 | EF0037 | Not tested | Not named | Protein | 1e-72 | 50 |
