Gene Information

Name : MGAS15252_0673 (MGAS15252_0673)
Accession : YP_005388720.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Virulence
Product : ABC transporter ATP-binding protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 654092 - 654802 bp
Length : 711 bp
Strand : +
Note : CDD hit: specific, cl999 = This family is comprised of MJ796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE). They a

DNA sequence : 
GTGTCGCATGAAAAAAAACAATTAATGCAATTATCAAATATTGTGAAGAGCTATCAAAATGGGGATCAAGTTCTTAAAGT
TTTGAAAGGTATTAATTTAACAGTATATGAGGGTGAATTTTTAGCTATTATGGGTCCGTCTGGCTCGGGAAAATCAACAC
TAATGAATATTATTGGTTTATTAGATCGGCCAACATCCGGAGATTACACATTACATAATACTAAAGTAGAAATCCTTAAT
GATCGTGAGTTAGCAAACGTACGAAATGATGAAATCGGCTTTGTCTTTCAACAATTCTTTCTGTTAGCTAAATTAACTGC
ATTACAAAATGTTGAGTTGCCTCTTATTTATGCTGGTGTAAACGTCTCAAAAAGACGTGAACAGGCTAAGCAATTTCTTG
AAAAAGTAGGACTTGGACGACGTATCAAACATCTACCGTCAGAACTGTCAGGAGGTCAAAAGCAAAGGGTGGCTATCGCA
CGAGCTTTAGTAAATGACCCATCTATTATTTTAGCGGATGAACCAACAGGTGCACTAGATACTAAAACAGGTCAGCAAAT
TATGGAACTCTTGACAGAGTTAAACAAAGAAGGTAAAACAATTATTATGGTTACTCATGAACCAGAAATTGCTGATTTTG
CAACTCGGAAAATTATTATTCGTGATGGTGATATCACAACGGATACTACAGCTAGTGTTGTTATTGACTAG

Protein sequence : 
MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIMGPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKVEILN
DRELANVRNDEIGFVFQQFFLLAKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKIIIRDGDITTDTTASVVID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-34 43
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-33 42
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 1e-33 42
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-33 42
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 3e-32 42
unnamed AAP55232.1 unknown Not tested SaPIbov2 Protein 2e-33 41
cur_1502 YP_001800896.1 cell division ATP-binding protein FtsE Not tested Not named Protein 2e-28 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MGAS15252_0673 YP_005388720.1 ABC transporter ATP-binding protein NC_012469.1.7686878. Protein 4e-75 75
MGAS15252_0673 YP_005388720.1 ABC transporter ATP-binding protein NC_008702.1.4606598. Protein 2e-44 49
MGAS15252_0673 YP_005388720.1 ABC transporter ATP-binding protein CP001581.1.gene798.p Protein 1e-35 44
MGAS15252_0673 YP_005388720.1 ABC transporter ATP-binding protein CP001581.1.gene598.p Protein 4e-37 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MGAS15252_0673 YP_005388720.1 ABC transporter ATP-binding protein VFG0869 Protein 5e-29 44