Gene Information

Name : mtsA (MGAS15252_0401)
Accession : YP_005388452.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Virulence
Product : metal (iron) ABC transport system substrate-binding lipoprotein MtsA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 375111 - 376043 bp
Length : 933 bp
Strand : +
Note : CDD hit: specific, cl262 = Metal binding protein PsaA. These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species. They belong to the TroA superfamily of periplasmic metal b

DNA sequence :
ATGGGAAAGAAAATGAGCCTCATTTTGGGTGCTTTTTTATCTGTTTTTCTTTTAGTAGCTTGTTCGTCAACTGGCACTAA
AACTGCTAAGAGTGATAAATTAAAAGTCGTGGCAACCAATTCAATTATTGCCGACATGACAAAAGCTATTGCTGGTGATA
AAATCGATCTGCACAGCATTGTGCCAATCGGTCAAGACCCTCATGAGTACGAACCATTACCAGAAGATGTTGAAAAAACA
AGTAATGCTGATGTGATTTTCTATAATGGTATCAATCTAGAAGATGGTGGGCAAGCTTGGTTCACCAAACTAGTGAAAAA
TGCTCAAAAAACGAAAAACAAAGATTACTTTGCCGTGTCTGATGGCATTGATGTGATTTACTTGGAAGGTGCAAGCGAAA
AAGGAAAAGAAGATCCACATGCTTGGTTAAATCTCGAAAACGGAATCATTTATTCAAAAAACATTGCCAAACAATTGATT
GCAAAGGATCCTAAAAACAAAGAAACTTATGAAAAGAACCTAAAAGCTTATGTGGCTAAATTGGAAAAACTAGACAAAGA
AGCCAAATCAAAATTTGATGCTATTGCAGAAAATAAAAAATTGATTGTGACTAGTGAAGGCTGCTTCAAGTACTTTTCAA
AAGCTTACGGTGTCCCATCTGCTTATATCTGGGAAATTAACACCGAAGAAGAAGGAACACCAGATCAAATTTCATCATTG
ATTGAAAAACTAAAAGTCACCAAGCCATCTGCGCTTTTTGTAGAGTCAAGTGTCGATAGACGCCCTATGGAAACTGTTTC
TAAAGATAGTGGTATTCCTATTTATTCTGAGATCTTTACAGATTCAATTGCTAAAAAAGGTAAACCTGGCGATAGTTATT
ATGCTATGATGAAATGGAACCTTGACAAAATTTCTGAAGGTCTAGCAAAATAA

Protein sequence :
MGKKMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKT
SNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSL
IEKLKVTKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0095 AAM75298.1 EF0095 Not tested Not named Protein 9e-107 75
EF0577 NP_814342.1 adhesion lipoprotein Virulence Not named Protein 1e-106 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mtsA YP_005388452.1 metal (iron) ABC transport system substrate-binding lipoprotein MtsA VFG1359 Protein 3e-113 77
mtsA YP_005388452.1 metal (iron) ABC transport system substrate-binding lipoprotein MtsA VFG2165 Protein 5e-87 57
mtsA YP_005388452.1 metal (iron) ABC transport system substrate-binding lipoprotein MtsA VFG2157 Protein 5e-78 51