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Name : fhuC (MGAS15252_0350) Accession : YP_005388402.1 Strain : Streptococcus pyogenes MGAS15252 Genome accession: NC_017040 Putative virulence/resistance : Virulence Product : ferrichrome transport ATP-binding protein FhuC Function : - COG functional category : - COG ID : - EC number : - Position : 325501 - 326283 bp Length : 783 bp Strand : - Note : CDD hit: specific, cl999 = ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD DNA sequence : ATGACAACAATTAGTGCTGAAGACCTCACAATTGCCTATGAACAGCGTACCATCATCGATAAATTATCGTTTTATATTCC TGAAGGTAAAATTACGACCATTATTGGCGCCAATGGCTGTGGGAAGTCTAGTTTATTAAAAGCACTGACAAGATTATTAC CACCAAAACAGGGAGTTGTATATTTAAATGGGCAAAACATTGCCACATTAGAAACTAAAGAGGTTGCTAAAAAACTAGCT CTTTTACCTCAAGTTCAAGAAGCAACTAACGGTATAACTGTTTACGAATTGGTTTCTTACGGACGTTTTCCCCATCAATC TTACTTTGGAAATCTTAGTCCAGCTGACAAAAAAGCCATTCATTGGGCTATGCAAGCCACCAATGTCATGGCCTATGCTG ATCAACCTGTTGATGCTCTTTCTGGGGGGCAACGTCAAAGGGTTTGGCTTGCAATGGCATTAGCCCAAGGCACTGATACT ATTTTTTTAGATGAGCCAACTACTTATTTAGATTTAAATCATCAACTAGAAATCCTAGAGCTCGTTAAATCCCTAAATAA GGATGCCGGCAAGACTATTGTTATGGTTCTTCACGACCTCAATCTTTCAGCCCGCTATTCGGATCATCTGATTGCTATGA AACATGGCAAGATCCATTATACTGGTACTATAGCAGATGTTATGACTTCACCTATCATTCAAGACATCTTCCAAATCAAA CCGGTACTGGTTGATGATCCTATCCACAACTGTCCTATAGTGCTGACTTATCAGCTTCAATAA Protein sequence : MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLA LLPQVQEATNGITVYELVSYGRFPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFQIK PVLVDDPIHNCPIVLTYQLQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| fagC | YP_005680307.1 | ATP binding cytoplasmic membrane protein | Not tested | PiCp 1 | Protein | 2e-58 | 47 |
| fagC | YP_003782430.1 | ABC transporter ATP-binding protein | Not tested | PiCp 1 | Protein | 2e-58 | 47 |
| fagC | YP_005682397.1 | ATP binding cytoplasmic membrane protein | Virulence | PiCp 1 | Protein | 2e-58 | 47 |
| fagC | YP_005684488.1 | ATP binding cytoplasmic membrane protein | Not tested | PiCp 1 | Protein | 2e-58 | 47 |
| iusE | YP_005143742.1 | iron ABC transporter ATP-binding protein | Virulence | Not named | Protein | 6e-59 | 46 |
| SPN23F_09560 | YP_002510939.1 | ferric siderophore ABC transporter ATP-binding protein | Virulence | PPI-1 | Protein | 2e-53 | 45 |
| SP_1035 | NP_345510.1 | iron-compound ABC transporter ATP-binding protein | Not tested | PPI-1 | Protein | 2e-53 | 45 |
| DIP0585 | NP_938961.1 | iron ABC transporter ATP-binding protein | Virulence | Not named | Protein | 1e-50 | 45 |
| fecE | AAL08451.1 | ATP-binding protein FecE | Virulence | SRL | Protein | 2e-52 | 44 |
| ciuD | YP_005681255.1 | Iron ABC transporter ATP-binding protein | Virulence | PiCp 4 | Protein | 6e-51 | 43 |
| ciuD | YP_005683346.1 | Iron ABC transporter ATP-binding protein | Virulence | PiCp 4 | Protein | 6e-51 | 43 |
| ciuD | YP_003783391.1 | iron ABC transporter ATP-binding protein | Virulence | PiCp 4 | Protein | 6e-51 | 43 |
| ciuD | YP_005685432.1 | Iron ABC transporter ATP-binding protein | Virulence | PiCp 4 | Protein | 6e-51 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| fhuC | YP_005388402.1 | ferrichrome transport ATP-binding protein FhuC | BAC0164 | Protein | 1e-52 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| fhuC | YP_005388402.1 | ferrichrome transport ATP-binding protein FhuC | VFG0925 | Protein | 3e-58 | 46 |
| fhuC | YP_005388402.1 | ferrichrome transport ATP-binding protein FhuC | VFG1042 | Protein | 9e-53 | 44 |
