Gene Information

Name : MGAS15252_0220 (MGAS15252_0220)
Accession : YP_005388280.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Virulence
Product : HasC-like UTP--glucose-1-phosphate uridylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 196116 - 197015 bp
Length : 900 bp
Strand : -
Note : CDD hit: specific, cl11394 = Prokaryotic UGPase catalyses the synthesis of UDP-glucose.; Prokaryotic UDP-Glucose Pyrophosphorylase (UGPase) catalyzes a reversible production of UDP-Glucose and pyrophosphate (PPi) from glucose-1-phosphate and UTP. UDP-gluc

DNA sequence :
ATGACCAAAGTCAGAAAAGCTATTATTCCCGCAGCAGGTTTAGGCACACGTTTTTTACCTGCAACCAAGGCCCTTGCCAA
GGAGATGCTACCTATTGTTGATAAACCAACTATTCAATTTATCGTTGAAGAAGCTCTAAAATCAGGTATCGAAGAAATTC
TTATCGTTACTGGAAAATCCAAACGCTCCATAGAAGATCATTTTGATTCTAATTTTGAATTAGAATATAATTTACAGGCT
AAAGGAAAAATCGAACTTCTAAAGTTAGTAGACGAGACCACTTCTATTAATCTTCACTTTATTCGACAGAGTCATCCAAG
AGGATTAGGAGACGCAGTTCTTCAAGCAAAGACCTTTGTTGGCAATGAACCTTTTGTTGTCATGCTAGGTGATGATCTGA
TGGATATTACAAATCCAAATGTAAAACCATTAACCAAACAATTGATCGATGACTATGAAGAAACTCATGCTGCAACTATT
GCCGTCATGAGGGTTCCTCACGAGGATGTCTCTAACTACGGTATCATTGCTCCTCAAGCAAAAGCAGTAAAAGGACTCTA
TAGTGTGGATACTTTTGTTGAAAAACCACAACCTCAAGATGCACCTAGTGATTTGGCAATTATTGGACGTTACTTGCTCA
CACCAGAAATTTTTAGTATTTTAGAAAAACAAGAACCTGGTGCAGGCAATGAAGTTCAACTGACTGATGCTATTGATACC
CTCAATAAGACACAGCGTGTCTTTGCTCGTGAGTTTAAAGGGAAACGCTATGATGTTGGCGATAAATTTGGGTTTATGAA
AACTTCTTTGGATTATGCCCTGAAACACCCTCAAGTCAAAGATGACTTGAAAGCCTACATCATCCAACTGGGCAAAGCAC
TAGAGAAGACAAAACCATAA

Protein sequence :
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQA
KGKIELLKLVDETTSINLHFIRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDT
LNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0059 YP_300149.1 UTP-glucose-1-phosphate uridylyltransferase Not tested SCC15305cap Protein 2e-74 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MGAS15252_0220 YP_005388280.1 HasC-like UTP--glucose-1-phosphate uridylyltransferase VFG0964 Protein 2e-133 91