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Name : leuS (MGAS15252_0183) Accession : YP_005388244.1 Strain : Streptococcus pyogenes MGAS15252 Genome accession: NC_017040 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase protein LeuS Function : - COG functional category : - COG ID : - EC number : - Position : 156888 - 159389 bp Length : 2502 bp Strand : + Note : CDD hit: specific, cl15 = catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core DNA sequence : ATGACATTTTACGATCACACCGCTATTGAACCCAAATGGCAAGCCTTTTGGGCAGATAATCATACTTTTAAAACAGGAAC AGACGCATCAAAACCTAAGTTTTATGCCCTAGATATGTTCCCATACCCATCAGGAGCTGGTCTCCACGTTGGTCACCCAG AAGGCTATACAGCAACTGATATTCTCAGCCGTTTCAAACGTGCCCAAGGTCACAATGTCCTCCACCCAATGGGGTGGGAT GCCTTTGGACTTCCTGCTGAGCAGTACGCTATGGATACTGGTAATGACCCAGCCGAGTTTACAGCTGAAAACATCGCTAA CTTCAAACGCCAGATTAATGCTCTTGGTTTCTCATACGACTGGGATCGTGAAGTTAACACAACTGACCCTAACTACTACA AGTGGACACAGTGGATCTTTACCAAGCTTTATGAAAAAGGCCTAGCCTACGAAGCTGAAGTTCCCGTTAACTGGGTTGAA GAATTGGGAACAGCTATCGCCAACGAAGAGGTTCTTCCAGATGGGACATCAGAACGTGGCGGCTACCCAGTTGTCAGAAA ACCCATGCGCCAATGGATGCTCAAAATCACTGCCTATGCAGAGCGCTTGCTAGAAGACTTGGAAGAAGTTGACTGGCCAG AATCAATCAAGGACATGCAACGCAACTGGATTGGTAAATCAACTGGTGCTAATGTAACCTTCAAGGTTAAGGATACAGAT AAGGACTTCACTGTCTTTACAACACGTCCTGACACGCTTTTTGGTGCAACTTACGCGGTTCTTGCTCCTGAGCATGCCTT GGTTGACGCTATTACGACAGCTGACCAGGCAGAAGCCGTTGCCGAATACAAACGTCAAGCAAGTCTCAAATCAGACCTTG CTCGTACAGACCTTGCCAAAGAAAAAACAGGTGTTTGGACGGGTAGCTACGCTATTAACCCAGTTAATGGTAACAAAATG CCAGTTTGGATTGCGGACTATGTCCTTGCTAGCTACGGTACTGGAGCTATCATGGCTGTTCCAGCCCACGATGAACGTGA CTGGGAATTCGCAAAACAATTTAACCTAGACATCATCCCTGTTCTTGAAGGTGGTAATGTTGAAGAGGCTGCCTTTACAG AAGACGGTCTTCACATCAACTCAGGCTTCCTAGATGGTCTTGACAAAGCGTCAGCTATTGCCAAAATGGTCGAATGGCTT GAAGCAGAAGGCGTCGGTAATGAAAAAGTCACTTACCGTCTCCGTGACTGGCTCTTTAGCCGCCAACGTTACTGGGGTGA GCCAATCCCAATCATCCACTGGGAAGATGGTACATCAACAGCGGTTCCTGAGAGTGAGTTGCCACTGGTTCTTCCAGTAA CTAAGGATATCCGTCCTTCAGGTACTGGTGAGAGCCCACTTGCTAACGTGACAGACTGGTTGGAAGTGACTCGTGAAGAT GGTGTGAAAGGTCGTCGTGAGACTAACACTATGCCACAATGGGCAGGTTCAAGCTGGTATTATCTTCGTTACATCGATCC ACACAACACCGAAAAACTGGCTGATGAGGAACTCCTCAAACAATGGTTGCCAGTTGATATCTATGTCGGTGGTGCAGAGC ATGCCGTGCTTCACCTTCTCTACGCTCGCTTCTGGCACAAGGTTCTTTACGATCTCGGTGTCGTACCAACCAAAGAGCCA TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACAAGCTACCGCGATAGCCGTGGTACTCTTGTGGCAACTGACAA GGTTGAAAAACGTGATGGTAGCTTCTTCCATGTGGAAACTGGGGAAGAGCTTGAACAAGCACCAGCTAAGATGTCTAAAT CACTTAAGAACGTTGTCAACCCAGATGATGTTGTTGAGCAGTACGGTGCTGACACTCTTCGTGTTTATGAGATGTTCATG GGACCACTTGACGCTTCCATCGCTTGGTCTGAAGAAGGTCTTGAAGGCTCACGTAGGTTCTTGGACCGTGTTCACCGTTT GATCACAACTAAAGAGATCACTGAGGAAAATAGCGGAGCCCTTGACAAGGTTTACAACGAAACTGTTAAGGCTGTTACTG AGCAAGTTGACCAAATGAAATTCAACACAGCTATCGCTCAACTCATGGTATTTGTCAATGCAGCCAACAAGGAAGACAAA CTCTTTAGCGACTATGCCAAAGGCTTCGTTCAATTGGTTGCACCATTTGCACCGCACTTAGGTGAGGAACTCTGGCAAGC CTTGACAGCCTCAGGTGAGTCAATCTCTTACGTGCCATGGCCAAGTTATGATGAAAGCAAATTGGTTGAAAACGATGTGG AAATCGTTGTCCAAATCAAAGGTAAGGTCAAAGCTAAACTTGTAGTTGCCAAAGACCTTTCACGCGAAGAATTACAAGAA GTTGCCCTTGCTAACGAAAAAGTCCAAGCCGAAATCGCAGGCAAAGACATCATCAAAGTCATCGCAGTACCAAACAAACT CGTTAATATTGTTATCAAATAG Protein sequence : MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWD AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNKM PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSGFLDGLDKASAIAKMVEWL EAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP FQKLFNQGMILGTSYRDSRGTLVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM GPLDASIAWSEEGLEGSRRFLDRVHRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK LFSDYAKGFVQLVAPFAPHLGEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 0.0 | 99 |
