Gene Information

Name : nga (MGAS15252_0175)
Accession : YP_005388237.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Unknown
Product : nicotine adenine dinucleotide glycohydrolase protein Nga
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 149288 - 150643 bp
Length : 1356 bp
Strand : +
Note : CDD hit: non-specific, cl1681 = Nicotine adenine dinucleotide glycohydrolase (NADase); This family consists of several bacterial nicotine adenine dinucleotide glycohydrolase (NGA) proteins which appear to be specific to Streptococcus pyogenes. NAD glycohy

DNA sequence :
ATGAGAAACAAAAAAGTAACATTAGCTCATATTGTCGCAAAGACAAGTGTTGCTATTGCTTTGGCTGGAGCAATGGGTAG
CAGTTTATTAGCTAATAGCACAACATACGCTGTTAGTGGCAAAGAAAATAAAAAAAGCGATGTCAAATATGAAACGACCA
AAGTTATGGAAGCTAACGCAACTTCCTCTAAAGAAGACAATCATGTCATGCACACATTAGACGGCTCAATGAGTACTGTC
TGGGAGGAAAATTCACCTGGTGGTGGTGTTGGTGAGGTACTTTCCTACAAGTTTGCGTCCCCGATGCGTATTGGGAGAAT
TTTAATTGTTAATGGAGATACATCTAGCAAGGAGAATTACTACAAGAAAAATAGAATTGCAAAGGCTGATGTTAAATACT
ATAACGGGAATAAATTGGTCCTCTTTCAAAAAATTGAATTAGGCGACACCTACACTAAAAAACCGCATCACATTGAGATT
GATAAAAAATTAGATGTTGATCGTATTGATATTGAGGTAACAGAGGTCCATCAGGGACAAAACAAGGATATTTTAGCCTT
GTCAGAGGTCACTTTTGGCAATATGGAACGCGATCTTTTTGAAAAAAAGTTTAAAGAAATTAAAGATAAATGGGTAACAG
ATAAACAAGCAGATGAGTTTATTGAAACTGCCGACAAGTATGCTGATAAAGCTGTTCAGATGTCTGCTGTTGCGTCACGT
GCTGAGTATTACCGGATGTATGTTAGCCGCAAATACCACTATAAAAAAGAGTTTGTTGAAAAACTAAAACAAGTCTACAA
AGAAAGCGGAGCTTCTCACGTTACAAGTAAAAAAGATTTGATGTTAGCTTTTGACGATGCTAAAAGAAAATCAACGATTG
GTCGACAAGAAAACGGTCTTTTTGTGACAAGTTTTGCTGAAGATATGGCATTGCTCTTTACTGATCAAGGTAAGTTAAAA
TCAGCTGACCAAATTGAAAATATAAAAGGTGTCGATAGCGGAAAATATAGTGATGGGGTTTATCAATATGAGTACGATTC
TGAACTAACAAAAAACATTGATAAGCTAGGCTATATCCGAACAGCTAGCGGAGATACTCCTGGAGCAAATTCGCTCAACA
TTCCTGGTTGCCAAACGTGGTCAGGAAAACACATTGAAAATTCAGAAAGTGAATTAATTTTCCCATCGATTAGTGTTAAA
GATCTAAAATCTAAAGCTGTCTTAGCAGAGATTGATGCCAAAGGCTATTTTGAAATTATTGATCCTACCATCATTGCTCC
AAATGGTGACCATAAAAAAGTAACTGGTCGCTTCAAAATTAAGAAAATGCAAGATAGAATGCAAGATAGGAAGTAA

Protein sequence :
MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENKKSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTV
WEENSPGGGVGEVLSYKFASPMRIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDLFEKKFKEIKDKWVTDKQADEFIETADKYADKAVQMSAVASR
AEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTSKKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLK
SADQIENIKGVDSGKYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESELIFPSISVK
DLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nga YP_281503.1 NAD glycohydrolase Not tested Not named Protein 0.0 99