Gene Information

Name : hasC (MGAS15252_1742)
Accession : YP_005389750.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Virulence
Product : UTP--glucose-1-phosphate uridylyltransferase protein HasC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1733484 - 1734398 bp
Length : 915 bp
Strand : +
Note : CDD hit: specific, cl11394 = Prokaryotic UGPase catalyses the synthesis of UDP-glucose.; Prokaryotic UDP-Glucose Pyrophosphorylase (UGPase) catalyzes a reversible production of UDP-Glucose and pyrophosphate (PPi) from glucose-1-phosphate and UTP. UDP-gluc

DNA sequence : 
ATGACCAAAGTCAGAAAAGCCATTATTCCTGCTGCAGGTCTAGGAACACGTTTTTTACCTGCTACCAAAGCTCTTGCCAA
AGAGATGTTGCCCATCGTTGATAAACCAACCATCCAGTTTATCGTCGAAGAAGCGCTAAAATCTGGCATCGAGGAAATCC
TTGTGGTGACCGGAAAAGCTAAACGCTCTATCGAGGACCATTTTGATTCAAACTTTGAATTAGAATACAACCTCCAAGCT
AAGGGGAAAAATGAACTGTTGAAATTAGTGGATGAAACCACTGCCATTAACCTTCATTTTATCCGTCAAAGTCACCCAAG
AGGGCTGGGAGATGCTGTCTTACAAGCCAAAGCCTTTGTGGGCAATGAACCCTTTGTGGTCATGCTTGGAGATGACTTAA
TGGACATTACAAATGCATCCGCTAAACCTCTCACCAAACAACTCATGGAGGACTATGACAAGACGCATGCATCCACTATC
GCTGTGATGAAAGTTCCTCATGAAGATGTGTCTAGCTATGGGGTTATCGCTCCTCAAGGCAAGGCTGTCAAGGGCCTTTA
CAGTGTAGACACCTTTGTTGAAAAACCACAACCAGAAGATGCGCCTAGTGATTTGGCTATTATTGGTCGTTACCTCCTAA
CCCCTGAAATTTTTGATATTTTGGAAAGACAGACCCCTGGAGCAGGTAACGAAGTGCAACTCACAGATGCTATCGATACC
CTCAATAAAACTCAGCGTGTCTTTGCACGAGAATTTAAAGGCAATCGTTACGATGTTGGGGATAAATTTGGATTCATGAA
AACATCTATCGACTATGCCTTAGAACACCCAGAGGTCAAAGAGGACTTGAAAAATTACATTATCAAACTAGGAAAAGCTT
TGGAAAAAAGTAAAGTACCAACACATTCAAAGTAA

Protein sequence : 
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQA
KGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFDILERQTPGAGNEVQLTDAIDT
LNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPEVKEDLKNYIIKLGKALEKSKVPTHSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0059 YP_300149.1 UTP-glucose-1-phosphate uridylyltransferase Not tested SCC15305cap Protein 5e-75 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasC YP_005389750.1 UTP--glucose-1-phosphate uridylyltransferase protein HasC VFG0964 Protein 2e-142 99