Gene Information

Name : cadX (MGAS15252_1684)
Accession : YP_005389692.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Resistance
Product : cadmium efflux putative regulatory protein CadX
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1688120 - 1688458 bp
Length : 339 bp
Strand : +
Note : CDD hit: specific, cl88 = Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several prote

DNA sequence : 
ATGAAAAAAGATAGTATCTGCCAAGTGAATGTTATAAATCAACAAAATGTTACAACCGCAACGAACTACCTTGAAAAGGA
AAAAGTCCAAAAATCACTTCGTATTTTATCAAAGTTTACCGATAATAAACAGATAAATATCATCTTTTATCTCCTTACTG
TTGAAGAACTCTGTGTCTGCGATATAGCCTGTTTACTAAATCTCAGTATGGCATCTGCCTCCCACCATCTTCGTAAACTA
GCCAATCAAAACATCTTGGACACTAGAAGAGAGGGGAAAATTATATATTATTTTATAAAAGATGAGGAAATCAGAGATTT
TTTTAATCAACTAGGATAA

Protein sequence : 
MKKDSICQVNVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQINIIFYLLTVEELCVCDIACLLNLSMASASHHLRKL
ANQNILDTRREGKIIYYFIKDEEIRDFFNQLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadX YP_254239.1 cadmium efflux system accessory protein CadX Not tested ¥ðSh1 Protein 4e-22 50
cadC YP_189777.1 CadC family transcriptional regulator Not tested vSe1 Protein 4e-21 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadX YP_005389692.1 cadmium efflux putative regulatory protein CadX BAC0059 Protein 2e-45 97