Gene Information

Name : MGAS15252_1569 (MGAS15252_1569)
Accession : YP_005389578.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Resistance
Product : ABC transport system ATP-binding component
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1575592 - 1576266 bp
Length : 675 bp
Strand : -
Note : CDD hit: specific, cl999 = This family is comprised of MJ796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of liporoteins from the cytoplasmic membrane (LolCDE). They a

DNA sequence :

TTGTTAAACCTTAAAGATATTCGAAAAAGCTATCATCTTGGAACTGAAGAATTTGCGATTTTAAAAGGAATCGATTTAGA
AGTTAACGAGGGTGACTTTTTAGCCATCATGGGACCATCAGGTTCGGGAAAGTCAACATTGATGAATATCATTGGGTGTT
TAGATAAGCCTGGCTCTGGCTCATATGCCATTGAAGGCAGAGACGTGTCATCCTTATCTGATAATGAACTTGCTGATTTG
CGTAATCAAAAAATCGGCTTTGTTTTTCAAAATTTTAACCTGATGCCCAAGCTAACAGCTTGTCAAAATGTCGAATTGCC
CTTGACTTATATGAATGTTCCTAAAAAAGAGCGTCGCAAACGAGCCCTAGAGATGTTAAAGCTAGTAGGACTAGAAGAAC
GTAGTGAATTTAAACCGATGGAGCTATCTGGTGGGCAAAAACAGCGTGTAGCGATTGCAAGAGCTTTAGTCACTAACCCG
AGTTTTATCCTTGGTGATGAGCCAACAGGTGCACTAGACACAAAAACCAGCGTCCAAATCATGGACCTATTTAAACAATT
CAATGATAACGGCAAAACGATTATTATCATCACACACGAGCCTGAAGTAGCTGCCTTATGCAAAAAGACGGTGATCCTAA
GAGATGGTAATATAGAACATTCCGATATAGAGTAA

Protein sequence :

MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADL
RNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEHSDIE

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
Spaf_1862	YP_006310627.1	amino acid ABC transporter ATP-binding protein	Not tested	FWisland_2	Protein	2e-36	43

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
MGAS15252_1569	YP_005389578.1	ABC transport system ATP-binding component	NC_012469.1.7686878.	Protein	2e-61	61
MGAS15252_1569	YP_005389578.1	ABC transport system ATP-binding component	CP001581.1.gene798.p	Protein	3e-38	46
MGAS15252_1569	YP_005389578.1	ABC transport system ATP-binding component	NC_008702.1.4606598.	Protein	3e-48	46