Gene Information

Name : secA (MGAS15252_1380)
Accession : YP_005389402.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1375090 - 1377609 bp
Length : 2520 bp
Strand : -
Note : CDD hit: specific, cl999 = Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helica

DNA sequence :
ATGGCCAATATTCTACGCAAAGTTATCGAAAATGACAAAGGCGAACTAAGAAAATTAGAAAAAATTGCAAAAAAAGTAGA
ATCCTACGCAGACCAAATGGCGTCATTGTCGGATAGAGATCTACAAGGAAAAACACTTGAATTTAAAGAACGCTATCAAA
AAGGTGAGACCCTCGAACAACTATTACCTGAAGCTTTCGCAGTTGTTCGTGAAGCAGCAAAACGTGTGTTGGGCTTGTTC
CCTTATCGTGTTCAAATTATGGGAGGAATTGTTCTTCATAACGGGGATGTCCCTGAAATGCGTACTGGTGAAGGAAAAAC
TCTTACAGCCACCATGCCAGTTTATCTCAATGCTATTGCTGGTGAGGGTGTTCACGTTATTACTGTTAATGAGTATCTTT
CAACGCGTGACGCTACCGAAATGGGTGAAGTGTATAGCTGGTTAGGTCTTTCAGTTGGGATCAACCTAGCTGCTAAGTCT
CCTGCTGAAAAACGTGAAGCTTATAATTGTGATATTACTTATTCAACCAACTCTGAAGTCGGTTTTGATTACCTTCGTGA
CAACATGGTTGTTCGCCAGGAAGACATGGTACAACGCCCACTCAATTTTGCCTTGGTTGATGAAGTGGACTCAGTCTTAA
TTGACGAGGCAAGGACACCTTTAATTGTTTCTGGTGCTGTTAGCTCTGAAACCAATCAATTGTATATTCGTGCTGACATG
TTTGTAAAAACTCTGACGTCAGTGGATTATGTTATTGATGTGCCCACTAAAACGATTGGATTAAGCGATTCAGGTATTGA
TAAAGCTGAGAGTTATTTTAACTTGAGCAATCTTTACGATATTGAAAATGTAGCCTTGACTCACTTTATAGACAACGCCC
TTCGTGCAAACTATATTATGTTGTTAGATATCGATTATGTGGTCAGCGAAGATGGTGAGATTCTTATTGTTGACCAATTT
ACAGGTCGTACGATGGAAGGGCGTCGCTTCTCAGACGGCTTGCACCAAGCTATTGAAGCAAAAGAAGGCGTTCGTATTCA
GGAAGAATCAAAAACCAGCGCCTCAATCACTTACCAAAATATGTTTCGTATGTACAAAAAATTGGCAGGTATGACTGGTA
CTGCGAAGACCGAGGAAGAAGAATTTCGCGAAGTTTATAACATGCGTATTATTCCAATTCCAACCAATCGTCCAATTGCC
CGTATTGATCACACTGATTTGCTTTACCCGACCTTAGAATCAAAGTTTAGAGCAGTTGTGGAAGACGTTAAAACGCGTCA
TGCAAAAGGACAACCTATCCTTGTAGGTACGGTTGCTGTTGAAACTAGTGATTTGATTTCACGCAAGCTGGTTGAAGCAG
GGATTCCTCATGAGGTTTTGAATGCTAAAAATCACTTTAAAGAAGCTCAAATCATTATGAATGCTGGGCAACGTGGTGCT
GTTACAATCGCAACTAACATGGCTGGTCGTGGTACTGATATCAAGCTTGGTGAAGGTGTTCGTGAACTTGGTGGGTTATG
TGTCATTGGTACAGAGCGTCATGAAAGCCGTCGTATCGATAACCAGCTTCGTGGACGTTCAGGTCGTCAAGGAGATCCAG
GTGAATCCCAATTCTATCTTTCATTAGAAGATGATTTGATGAGACGTTTTGGCTCTGATCGTATAAAAGCCTTTTTGGAT
CGGATGAAATTAGATGAAGAAGACACTGTTATTAAATCAGGTATGTTAGGGCGTCAAGTGGAATCTGCTCAAAAACGGGT
TGAAGGAAATAACTACGATACCCGTAAACAGGTCTTACAATACGATGATGTGATGCGTGAACAGCGTGAAATTATCTATG
CTAACCGTCGTGATGTCATAACTGCTAATCGAGATCTTGGCCCAGAAATTAAAGCTATGATCAAGCGTACTATCGACCGT
GCTGTAGATGCTCATGCACGTAGCAATCGTAAAGATGCTATAGATGCTATTGTAACTTTTGCTAGGACCTCGCTGGTACC
AGAAGAGTCTATTAGTGCTAAAGAGTTACGTGGTTTAAAAGATGATCAAATCAAAGAGAAGCTTTATCAAAGAGCGCTTG
CTATCTATGACCAACAACTATCAAAACTTCGTGATCAAGAAGCTATTATTGAATTCCAAAAAGTACTCATTTTGATGATT
GTGGATAACAAATGGACTGAACACATTGATGCCTTAGATCAACTTCGTAATGCTGTTGGACTTCGGGGGTATGCTCAAAA
TAACCCTGTGGTGGAATACCAAGCAGAAGGTTTCAAGATGTTCCAAGATATGATTGGTGCTATCGAGTTTGATGTAACAC
GTACCATGATGAAAGCACAAATTCACGAACAAGAACGTGAACGTGCAAGTCAACGTGCCACAACAGCAGCACCTCAAAAC
ATCCAATCGCAGCAGTCAGCTAACACCGATGATTTACCCAAAGTGGAGCGTAACGAAGCTTGTCCATGTGGTTCAGGCAA
AAAATTCAAAAATTGTCACGGTCGTAAATCCTTCTCATAA

Protein sequence :
MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLF
PYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADM
FVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQF
TGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA
RIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLD
RMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDR
AVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDDQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMI
VDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAPQN
IQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-143 41