Gene Information

Name : htsC (MGAS15252_1372)
Accession : YP_005389394.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Virulence
Product : heme ABC transport system ATP-binding protein htsC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1363808 - 1364644 bp
Length : 837 bp
Strand : -
Note : CDD hit: specific, cl999 = ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD

DNA sequence :
ATGAGTAAGAACAGCAGTCATATTCAGGTGCAAAACCTTTCCTTTGCTTATGAGGAAAAACTTGTTTTAGATGACCTGAC
CTTTAGCATTCCAAAAGGGAAAATTACCACTATTATGGGGGCAAATGGCAGTGGCAAGTCAACCTTATTACAATTATTAA
CCAAAAACCTTCCGTTAAAACAAGGGCAGGTTTGGCTTGAGCAGGAAGAATTAGCAACGATTTCTCTCAAGGCTTTTGCG
AAAAAAGTGGCAGTGGTACACCAATACCATCAAGTGGTCGAAGGTTTGTTAGTGGGTGAATTGGTAGCCATGGCTAGGCT
TGCCCGTCGTTCTTTTTTTAAAACTACTACCAAAGAAGATGAGGAACGCCTTGCTTGGGCCTTAGAAGTAACGGCTTTGA
GTGATTATGTTTATCGTGACATCCAACACCTTTCTGGTGGTGAACAGCAGAGGGTTTGGATTGCCATGGCCCTTGCCCAG
GATACAGATATTATTTTTTTAGATGAGCCAACGACTTATTTGGATATTAAGTACCAGCTTGACATTCTCAAGCTGATTAC
TAAAATCAACCAAGAGCTAGGCCTAACGATTGTGTTAGTATTACATGACATCAATCAGGCCTTATCTCTTTCAGACCATC
TTATTGGACTGAAAGATGGGCGACTTTATGCCCAAGGGCAACCAAGAGACCTCCTTGATCAACAGTTTATCAGAGATGTC
TTTGGTGTTGAATTGCCCTTTGTTGAGAGAAATGGTCAACAGTTTGTCCTCACTTCATTGGTCAATGAAACCAATGATAT
TAGAACTCAAAGGAGAGATAGGAACAAGAACAGATGA

Protein sequence :
MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGSGKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFA
KKVAVVHQYHQVVEGLLVGELVAMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLKDGRLYAQGQPRDLLDQQFIRDV
FGVELPFVERNGQQFVLTSLVNETNDIRTQRRDRNKNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 6e-38 41
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 6e-38 41