Gene Information

Name : serS (MGAS15252_1329)
Accession : YP_005389351.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1322160 - 1323437 bp
Length : 1278 bp
Strand : +
Note : CDD hit: specific, cl268 = Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent form

DNA sequence :
ATGCTAGATCTTAAACGTATCCGTACCGATTTTGACACTGTCGCTGCCAAATTAAAAAACCGCGGTGTTTCTGAAGACAC
CCTGACCCATCTTAAAGAACTTGATGAAAAACGTCGTGCTCTATTAGTGCAATCAGAAGAATTAAAAGCAGAGCGTAATA
TTGCTTCTGCAGCCATCGCCCAAGCAAAACGTCAAAAAGAAGATGCCACTCAACAAATTGCTGATATGCAAAAAGTCTCT
GCAGATATCAAAACTATTGACAATCAACTAGTAGCTATCGACCAGCAAGTTACTGACATCATCACTGTTTTACCTAATAC
TCCTCACGATTCTGTCCCTGTTGGAGCTGACGAAGAAGACAATGTCGAAATTCGCCGTTGGGGAACGCCTCGTGACTTTG
ACTTCGAAGTTAAGGCTCATTGGGATCTAGGCGAAGATCTTGATATTTTAGACTGGGAACGTGGGGCAAAGGTAACTGGT
GCTCGTTTCTTATTCTATAAAAATCTTGGTGCTCGTTTGGAGCGTGCTCTTTATAACTTCATGCTGGATGAACATATCAA
AGAAGGTTATCAAGAAATCATCACACCTTACATGGTTAACCACGATTCCATGTTTGGTACAGGACAATATCCAAAATTCA
AAGAGGACACCTTTGAATTAGCAGATACCAACTTTGTCCTGATTCCAACTGCTGAAGTGCCTTTGACCAATTATTACCGT
GGGGAAATCCTAGACGGCAAAGAATTGCCAATTTACTTTACTGCAATGAGCCCATCTTTTCGTTCTGAAGCGGGTTCTGC
GGGTCGTGACACACGTGGCCTTATCCGCCTACACCAATTCCACAAAGTTGAGATGGTTAAATTTGCTAAACCAGAAGAAT
CTTACCAAGAACTAGAAAAAATGACTGCTAATGCTGAAAATATTCTTCAAAAACTTGGTTTGCCATATCGCGTCATTTCC
CTTTGTACTGGAGACATGGGCTTCTCAGCTGCTAAAACTTATGACCTTGAAGTCTGGATTCCAGCTCAAAATACCTATCG
TGAAATTTCATCATGTTCAAATACAGAAGATTTCCAAGCACGTCGTGCTCAAATCCGTTACCGTGATGAGGCTGACGGTA
AGGTTAAACTTCTCCACACCCTTAATGGGTCAGGACTTGCTGTCGGTCGTACCGTAGCAGCCATTTTAGAAAACTACCAA
AATGAAGATGGTTCTGTTACCATCCCTGAAGTACTCCGCCCTTACATGGGTGGCGAAACCGTCATTTCACCTAAATAA

Protein sequence :
MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQSEELKAERNIASAAIAQAKRQKEDATQQIADMQKVS
ADIKTIDNQLVAIDQQVTDIITVLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELADTNFVLIPTAEVPLTNYYR
GEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVIS
LCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQ
NEDGSVTIPEVLRPYMGGETVISPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-176 83