Gene Information

Name : nadE (MGAS15252_1253)
Accession : YP_005389276.1
Strain : Streptococcus pyogenes MGAS15252
Genome accession: NC_017040
Putative virulence/resistance : Unknown
Product : NAD synthetase protein nadE
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1248575 - 1249399 bp
Length : 825 bp
Strand : -
Note : CDD hit: specific, cl292 = NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The

DNA sequence :
ATGACACTACAAGAAGAGATAATTCGACAATTAGGCGTCAAGGCTAGCATTGACCCACAAGAAGAAATTCGGAAAGCCGT
TGATTTTTTAAAAGCTTATTTGCGTAAGCACTCATTTTTAAAAACTTATGTCTTAGGCATTTCGGGAGGTCAGGATTCTA
CCCTCGCAGGAAAGCTAGCCCAAATGGCCATTGCAGAGTTACGGGAGGAAGCAAGTGATCAAGCTTACCAATTTATAGCT
GTTCGCTTGCCTTATGGGGTTCAGGCTGATGAAGCAGATGCGCAAAAAGCCTTGGCTTTTATTGCACCAGATCAGACCCT
TACCATTAATATCAAGGCAGCTGTGGACGGTCAAGTAGAGGCTCTACAAGCAGCAGGCGTTGAGATTTCTGATTTCAATA
AAGGTAATATTAAAGCACGTCAGCGAATGATCAGTCAATATGCCATTGCTGGCCAAATGGCTGGTGCTGTTATTGGAACG
GATCATGCGGCAGAAAACATCACTGGTTTCTTTACTAAATTTGGTGATGGTGGAGCAGATATTCTTCCCCTCTTTAGGCT
TAACAAACGTCAAGGAAAGGCTCTTTTGAAAGTTTTAGGAGCAGATGCTGCTTTGTATGAAAAAGTTCCAACTGCTGATT
TAGAAGATCAAAAACCAGGCTTGGCTGATGAGGTTGCTCTAGGGGTGACCTATCAAGACATCGACGACTATTTGGAAGGG
AAGCTGATTTCCAAAGTAGCTCAAGCAACTATTGAAAAATGGTGGCATAAAGGACAACACAAGCGTCACCTGCCAATCAC
CATTTTTGATGATTTTTGGAAATAA

Protein sequence :
MTLQEEIIRQLGVKASIDPQEEIRKAVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAELREEASDQAYQFIA
VRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVALGVTYQDIDDYLEG
KLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 8e-62 54