Gene Information

Name : Mtc_2214 (Mtc_2214)
Accession : YP_005381467.1
Strain : Methanocella conradii HZ254
Genome accession: NC_017034
Putative virulence/resistance : Resistance
Product : copper-translocating P-type ATPase/ heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.3
Position : 2102541 - 2104925 bp
Length : 2385 bp
Strand : +
Note : -

DNA sequence :
ATGGAACACGAAAAAGGTACATGCGGCTGTGACTCATGCCGCGACGGCGATACGGTGGCGGAAGCGCAGGTCTGCCGCAT
CGAGCCGGAGGGACAGGGGCCGCCCAGGAAAACGGATTTTAAGATCGACAACCTGGATTGCATGGACTGCGCACAAAAGC
TGGAACAGCGCATCGCGAAGCAGCCGGGCGTAATATCCGCACGGCTCAACTTCGGCACCTCGACGATAAACATAGAGCAC
ACGGGACCGACATCCGCTCTCCTGGACATAATCGAGCAGTCGGGATACCACGTATCGGCCGAGAATTTCAAGATAACCGA
GTTCGAAGTGAAAGAGCTGGATTGTATCGATTGCGCTAATAAGTTCGAGAAGGCCATCCAGATGGCGCCCGGCGTCATCC
GGGCCACCCTTAATTTCTCCATAGGCAAGCTCACGGTGGAGCACACATGCCCCGTAGAAGAGATAATAGATGCCGCTCAC
GATATTGGCTATACGATTACCGTTGCTGGCGTTACGAAAAAAGAATCGTTCGTAACCCGCTATAGGCCGATGATAGTCAC
AGTGGTATCCGGCCTTTTTACCATAGCCGGATTCATATCGGGCTTCTTGAGCGCGCCCTCATACGTCCCTATCGCTTTAT
ACTTTATGGCCATCGCCATTGGAGGATACCATGTGGCGAAGAGCGCCCTGTACTCGTTAAAGACGCTGACGGCGGACATG
AACCTGCTGATGGCCATCGCGGTCATCGGCGCAATGGCCATAGGCCAGTGGGAAGAGGGGGCGACCGTCGTCGTATTATT
CGCGCTCGGGAACGCGCTGCAATCCTTTACGCTCGATAAGACGAGGGACTCTATAAAAGAGCTTATCACACTATCGCCGA
AGGAGGCCACCGTGCTCAGGAATGGCAAGGGGGTAAAGCTAAACACCGGGCTCATCAACGTGGGCGACGTAATAGTCGTG
AAGCCAGGCGAAAAGATACCCATGGACGGCGTGGTCATCGAGGGGTCATCTTACGTGAACCAGGCGCCGATCACGGGCGA
GCCCATCCCCGTTGAAAAGATGCAGGGCAGCGAAGTCTATGCCGGAACCATTAATGGGAACGGCGCCCTGGAAATAAAAG
TGACAAAGCTGGCAAAGGATAATACCCTGAGCAAGATCATCCATATGGTGGAAGAGGCGCAGGTTCATAGGGCCCCAACG
CAGGTGTTCCTGGATAGGTTCACGAAGTATTATACGCCCGCCGTGATAGCCCTGGCGGCGGGGGTGGCCATCATACCCAC
ACTGATGGGCCAGCCGCTCTATCCATGGCTTTACCGTGGCCTGGTACTGCTGGTCATATCATGCCCCTGCGCATTGGTCA
TATCCACTCCTGTCTCCATAGTGGCGGCGATCGGCAGCGCGTCTCGTAACGGGGTGCTCATCAAAGGCGGCAACTACCTT
GAGGAGATAGGCAGGGCGAGGGCCATAGCGTTCGACAAGACAGGTACGCTGACGAAAGGCCAGCCCATCGTATCTGACGT
CATCACCTTCGATTCCTATGACAGGGACGAGATCATCGGCATCGCTGCCTCGCTTGAGTCTAAGTCTGGCCATCCTCTCG
CTCAGGCCATACTCAGGGCACACCATAATAGGCCCACCATGCCGGTCACTAATTTCGAGTCCATAACGGGTAAAGGCATT
AAAGGCTCCATAGGCGGTAAGGAGTACAGCCTGGGCAACATCAAGATGTACGAGTCGGTCGGGGAGGACGTGCTAAAAAC
TGTAAACCAGCTACAGGAAGCCGGCAAGACGCCGGTCATCCTGGGCGAGGGCAACAAGGCGATGGCCGTCATCGCCATCT
CTGACGAGATCAGGCCTGAGAGCAGGCAACTGGTGTCCGATCTGCATAAGGCAGGGCTTAAAGAGGTCATAATGCTCACC
GGGGATAACAGGCGGATGGCTAAAGCAATAGCGAGCGACATCGGCCTGGACGGCTATTTTGCCGATTTGCTGCCTGAGGA
AAAGGCGAACATCGTGAGAGGCATAAGGAAGGCCCACGGTAACGTCATCATGGTCGGCGACGGAGTAAATGACGCCCCGG
CCCTGGTCGCGTCTAACGTGGGCATCGCTATGGGCGCCACCGGCTCGGACACGGCCCTGGAGAACGCCGACATTGCGCTA
ATGGCCAATGACCTCTCTAAGGTAGACTATACCATAAGGCTGGGGCGGCGGACGCTTAAAATAATAAAGGAGAACGTGGG
CTTTGCCATCGCCATCAAGGCTCTCTTCATCGGCCTCGCCATCCTGGGCGTGGCGAACCTGTGGATGGCCGTGTTCGCGG
ACATGGGCGCCTCGCTCATAGTGATATTGAATGGCATGAGGCTCCTCCATGCCCATGCTGGATGA

Protein sequence :
MEHEKGTCGCDSCRDGDTVAEAQVCRIEPEGQGPPRKTDFKIDNLDCMDCAQKLEQRIAKQPGVISARLNFGTSTINIEH
TGPTSALLDIIEQSGYHVSAENFKITEFEVKELDCIDCANKFEKAIQMAPGVIRATLNFSIGKLTVEHTCPVEEIIDAAH
DIGYTITVAGVTKKESFVTRYRPMIVTVVSGLFTIAGFISGFLSAPSYVPIALYFMAIAIGGYHVAKSALYSLKTLTADM
NLLMAIAVIGAMAIGQWEEGATVVVLFALGNALQSFTLDKTRDSIKELITLSPKEATVLRNGKGVKLNTGLINVGDVIVV
KPGEKIPMDGVVIEGSSYVNQAPITGEPIPVEKMQGSEVYAGTINGNGALEIKVTKLAKDNTLSKIIHMVEEAQVHRAPT
QVFLDRFTKYYTPAVIALAAGVAIIPTLMGQPLYPWLYRGLVLLVISCPCALVISTPVSIVAAIGSASRNGVLIKGGNYL
EEIGRARAIAFDKTGTLTKGQPIVSDVITFDSYDRDEIIGIAASLESKSGHPLAQAILRAHHNRPTMPVTNFESITGKGI
KGSIGGKEYSLGNIKMYESVGEDVLKTVNQLQEAGKTPVILGEGNKAMAVIAISDEIRPESRQLVSDLHKAGLKEVIMLT
GDNRRMAKAIASDIGLDGYFADLLPEEKANIVRGIRKAHGNVIMVGDGVNDAPALVASNVGIAMGATGSDTALENADIAL
MANDLSKVDYTIRLGRRTLKIIKENVGFAIAIKALFIGLAILGVANLWMAVFADMGASLIVILNGMRLLHAHAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-143 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-143 43
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-143 43